703 research outputs found
Exposé de la situation financière de la Société
Mermod . Exposé de la situation financière de la Société. In: Annales de la Société botanique de Lyon, tome 5, 1876-1877. 1878. p. 41
Situation financière de la Société
Mermod . Situation financière de la Société. In: Annales de la Société botanique de Lyon, tome 6, Compte-rendu des séances – 1877-1878. 1879. p. 92
Nuclear factor I genomic binding associates with chromatin boundaries
BACKGROUND: The Nuclear Factor I (NFI) family of DNA binding proteins (also called CCAAT box transcription factors or CTF) is involved in both DNA replication and gene expression regulation. Using chromatin immuno-precipitation and high throughput sequencing (ChIP-Seq), we performed a genome-wide mapping of NFI DNA binding sites in primary mouse embryonic fibroblasts. RESULTS: We found that in vivo and in vitro NFI DNA binding specificities are indistinguishable, as in vivo ChIP-Seq NFI binding sites matched predictions based on previously established position weight matrix models of its in vitro binding specificity. Combining ChIP-Seq with mRNA profiling data, we found that NFI preferentially associates with highly expressed genes that it up-regulates, while binding sites were under-represented at expressed but unregulated genes. Genomic binding also correlated with markers of transcribed genes such as histone modifications H3K4me3 and H3K36me3, even outside of annotated transcribed loci, implying NFI in the control of the deposition of these modifications. Positional correlation between + and - strand ChIP-Seq tags revealed that, in contrast to other transcription factors, NFI associates with a nucleosomal length of cleavage-resistant DNA, suggesting an interaction with positioned nucleosomes. In addition, NFI binding prominently occurred at boundaries displaying discontinuities in histone modifications specific of expressed and silent chromatin, such as loci submitted to parental allele-specific imprinted expression. CONCLUSIONS: Our data thus suggest that NFI nucleosomal interaction may contribute to the partitioning of distinct chromatin domains and to epigenetic gene expression regulation. NFI ChIP-Seq and input control DNA data were deposited at Gene Expression Omnibus (GEO) repository under accession number GSE15844. Gene expression microarray data for mouse embryonic fibroblasts are on GEO accession number GSE15871
First record of the Red Sea immigrant Chrysallida fischeri (Hornung and Mermod, 1925) (Gastropoda: Pyramidellidae) from Greek waters
The Red Sea mollusc Chrysallida fischeri (Hornung and Mermod, 1925) was collected in 2005 off Makri, Rhodes, Greece. This is the first record of the species in the Aegean Sea. The presence of both live specimens and shells suggest that C. fischeri is well established in the area. © 2007 The Author(s)
Debrot, S., Fivaz, G., Mermod, C. et Weber, J.M. — Atlas des poils de mammifères d'Europe. Neuchâtel, Institut de Zoologie de l’Université (22, chemin de Chantemerle, CH 2000 Neuchâtel), 1982
Bourlière François. Debrot, S., Fivaz, G., Mermod, C. et Weber, J.M. — Atlas des poils de mammifères d'Europe. Neuchâtel, Institut de Zoologie de l’Université (22, chemin de Chantemerle, CH 2000 Neuchâtel), 1982. In: Revue d'Écologie (La Terre et La Vie), tome 37, n°1, 1983. p. 136
Discovery Potential of R-Hadrons with the ATLAS Detector at the LHC
R-hadrons are predicted in a range of supersymmetric scenarios including split-supersymmetry and gauge-mediated supersymmetry breaking. In this talk, the discovery potential of the ATLAS experiment for gluino and stop-based R-hadrons is outlined. A range of final state observables such as high transverse momentum muon-like objects and information on ionization energy loss are used. It is shown that ATLAS would be able to discover such particles at comparatively modest amounts of luminosity (1fb-1) for masses up to 1 TeV
Right-handed neutrinos: the hunt is on!
The possibility of the existence of right-handed neutrinos remains one of the most important open questions in particle physics, as they can help elucidate the problems of neutrino masses, matter-antimatter asymmetry, and dark matter. Interest in this topic has been increasing in recent years with the proposal of new experimental avenues by which right-handed neutrinos with masses below the electroweak scale could be detected directly using displaced-vertex signatures. At the forefront of such endeavours, the proposed SHiP proton beam-dump experiment is designed for a large acceptance to new weakly-coupled particles and low backgrounds. It is capable of probing right-handed neutrinos with masses below 5~GeV and mixings several orders of magnitude smaller than current constraints, in regions favoured by cosmology. To probe higher masses (up to 30~GeV), a promising novel approach is to identify displaced vertices from right-handed neutrinos produced in decays at LHC experiments
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