2,169 research outputs found
Redbird Buzz Episode 15: Dr. Mary Manz Simon \u2769, December 6, 2022
No full textAuthor and educational consultant Dr. Mary Manz Simon ’69 joins Redbird Buzz to share her unique path from kindergarten teacher to children’s author and educational consultant for companies like Crayola, DreamWorks, Sony, and more. Simon shares what is truly important when it comes to passion, shaping the lives of children as educators, and how learning each day ourselves makes us a better person. She also gives a brief insight into her friendship with beloved television host Mr. Fred Rogers
Lipid nanotubule fabrication by microfluidic tweezing
No full textThere is currently great interest in the development of lipid enclosed systems with complex geometrical arrangements that mimic cellular compartments. With biochemical functionalization, these soft matter devices can be used to probe deeper into life's transport dominated biochemical operations. In this paper, we present a novel tool for machining lipid nanotubules by microfluidic tweezing. A bilayer poly(dimethylsiloxane) (PDMS) device was designed with a lipid reservoir that was loaded by capillary action for lipid film deposition. The lipid reservoir is vertically separated from an upper flow for controlled material wetting and the formation of giant tubule bodies. Three fluidic paths are interfaced for introduction of the giant tubules into the high velocity center of a parabolic flow profile for exposure to hydrodynamic shear stresses. At local velocities approximating 2 mm s(-1), a 300-500 nm diameter jet of lipid material was tweezed from the giant tubule body and elongated with the flow. The high velocity flow provides uniform drag for the rapid and continuous fabrication of lipid nanotubules with tremendous axial ratios. Below a critical velocity, a remarkable shape transformation occurred and the projected lipid tubule grew until a constant 3.6 mu m diameter tubule was attained. These lipid tubules could be wired for the construction of advanced lifelike bioreactor systems
Theorie und Praxis der Sozialpolitik in der DDR. Herausgegeben durch Gunter Manz und Gunnar Winkler.
No full textWinkler (Gunnar) GB.23
Andreas Manz - Pioneer, Mentor, Friend
No full textMicrofluidics – as most of us call their research field today; micro total analysis systems as it was named at the beginning of the 1990s, was heavily influenced by contributions from Andreas Manz. The first inventions and publications in the field of analytical chemistry, such as electrophoresis-on-chip and chromatography-on-chip, showed the amazing potential of miniaturized systems. The pioneering work for separation methods was followed by further seminal studies on bioanalytical and biological applications of microfluidic chips, such as PCR-on-chip, adaptations to various analytical detection methods, chemical reactors; and numerous more fancy ideas, such as powder-on-chip, leaves as molds, or the miniaturized London city map, with shortest travel distances visualized by a gas plasma. The world of microfluidics has very creative aspects and Andreas was one of the catalysts for the next generation of researchers.</p
Título: De Ecclesia Christi commentariorum libri quinque
No full textTexto con notas a pie de págVol. I (X, 142 p.) -- vol. II (XXVIII, 860 p.
Manz Beatrice, Power, Politics and Religion in the Medieval Middle East : Iran under the Timurids. Cambridge, Cambridge University Press, 2007
No full textAigle Denise. Manz Beatrice, Power, Politics and Religion in the Medieval Middle East : Iran under the Timurids. Cambridge, Cambridge University Press, 2007. In: Bulletin critique des annales islamologiques, n°27, 2012. p. 99
Ultrasensitive PCR and real-time detection from human genomic samples using a bidirectional flow microreactor
No full textIn this paper we present a reliable bidirectional flow DNA amplification microreactor for processing real-world genomic samples. This system shares the low-power thermal responsiveness of a continuous flow reactor with the low surface area to volume ratio character of stationary reactors for reducing surface inhibitory effects. Silanization with dimethyldichlorosilane in combination with dynamic surface passivation was used to enhance PCR compatibility and enable efficient amplification. For realtime fragment amplification monitoring we have implemented an epimodal fluorescent detection capability. The passivated bidirectional flow system was ultrasensitive, achieving an RNase P gene detection limit of 24 human genome copies with a reaction efficiency of 77%. This starts to rival the performance of a conventional real-time PCR instrument with a reaction efficiency of 93% and revitalizes flow-through PCR as a viable component of lab on a chip DNA analysis formats
Intermittently operated slow sand filtration: a new water treatment process
No full textBibliography: p. 168-173.Access to potable water supplies is a great problem in the developing world. Many attempts have been made to develop a cheap, effective and robust way of treating water at a household scale but none have gained wide acceptance. In early 1991 Dr. Manz developed a hypothesis which would allow the adaptation of continuous slow sand filtration to intermittent use. After several studies which showed the effectiveness of filters operated in this way, this research was commenced to more closely examine intermittently operated slow sand filtration. The investigation showned the filter is effective in removing 96% of faecal coliform indicators and that this can be further improved. A mathematical model of oxygen transfer into the filter bio-layer was developed and is supported by experimental data. Removals of contaminants occurred in two phases. First capture or interception and second, metabolism and consumption of contaminants. Design and operation recommendations may improve the effectiveness future designs and identified possible areas for future research
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