13 research outputs found
Soldiers and criminal activity – causes and consequences (US and Slovenian armies)
No full textPogoj za vstop v vojsko je tudi preteklost kandidata, predvsem njegova nekaznovanost. Gre za pogoj, ki je običajno prisoten pri zaposlovanju javnih uslužbencev, še toliko pomembnejši pa je v poklicih, kot je vojska ali policija. Ta pogoj je bil skozi čas bolj oz. manj strogo upoštevan, predvsem odvisno od števila potrebnih in prijavljenih kandidatov za vojsko, vedno pa obstajajo dejanja, ki so neoprostljiva. Kandidati morajo za vsa kriminalna dejanja dobiti tako imenovane odpustke, kljub nasprotnemu splošnemu mnenju pa nobeno kriminalno dejanje ni zapečateno. Pomembnost preteklosti kandidatov in pozneje vojakov, sploh tistih, ki so odpustke dobili za dejanja, ki so jih izvedli že kot odrasle osebe, je izjemnega pomena, saj obstaja veliko večja verjetnost, da bo že pred vpoklicem aretiran kandidat za zaposlitev povzročal dejanja, ki bodo razlog odpustka. Samo kriminalno dejanje ni zadostna informacija, na podlagi katere bi lahko oblikovali zaključke o nadaljnjih dejanjih, ampak je to veliko drugih dejavnikov, kot so: izobrazba, socialne okoliščine, iz katerih vojak prihaja ali v katere nekdanji vojak odhaja, stanje, v katerem je družba, na podlagi katere lahko bolje razumemo izpostavljen pomen merila nekaznovanosti.One of the army entry conditions is candidate\u27s background, particularly their lack of criminal convictions. It is a condition that is usually present in the public administration recruitment but is even more important in professions such as the army or the police. This condition has been followed more or less strictly over time, mainly depending on the number of required and registered candidates for the army, but there are always actions that are inexcusable. Candidates must obtain so-called moral (conduct or felony) waivers for all criminal acts. Despite the contrary general opinion, no criminal act is sealed. The importance of the past of candidates and later soldiers, especially those who received moral waiver for acts committed as adults, is of utmost importance, as there is a much greater likelihood that a candidate who has been arrested before conscription will commit acts that will lead to a pardon. A single criminal act is not sufficient information on which to base conclusions about further actions, many other factors, such as education, the social circumstances from which the soldier comes or to which the former soldier returns, and the state of the society, allow for a better understanding of the significance of the importance of the criterion – having no criminal record
Developing social skills of a third grade asperger's syndrome student in the classroom
No full textChildren with Asperger syndrome have deficits in social skills, which makes it impossible for them to be as successful in social situations as their peers. Targeted teaching of social skills help them understand what other children take for granted, which is an important contribution to improving the quality of their lives. Targeted teaching of social skills can take place in a group, e.g., in peer groups, or individually, e.g., as a part of additional specialist assistance aimed at overcoming the child's deficits. Targeted teaching presumes prior knowledge of the degree of development of single skills, and is followed by the preparation of activities aimed at improving the child's functioning using these skills. Targeted teaching consists of examining the understanding, and monitoring the degree of adoption of the skills that are taught. The purpose of such teaching is the acquisition of social skills to successfully operate in various social situations; the skills are acquired through pre-prepared activities, such as role playing, social stories, empathy toward another person, and others. When targeted teaching takes place within a group, such as a class, the involvement of classmates is the closest imitation of the kind of social environment in which a learner with Asperger syndrome will have to function independently. In this manner, the learner is enabled to practice in the social environment that needs to be adopted. This increases the possibilities for a successful adoption of concerned social skills.
The purpose of this research was to test the program of developing social skills with a learner with Asperger syndrome in her class, and to determine the impact of this program on her classmates who also participated in the program. Treating people with Asperger syndrome is prevalently done individually, although this does not favor their social skills development. The case study of this research included one learner, aged eight, in her third grade of primary school. In the statement of special needs, the learner was defined as a child with autism spectrum disorders, i.e., a child with moderate deficits in social communication and social interaction, and a child with moderate deficits in behavior, interests, and activities (Asperger syndrome). By definition, social skills include social interaction, which is the reason why the entire third-grade class—a total of 21 pupils—was included in the program. The program was planned to take into account specific functioning characteristics of children with Asperger syndrome. Moreover, it was adapted to the level of development of the learner's social skills. The research also involved the learner's parents, the class teacher, as well as the special and rehabilitation teacher who carries out additional specialist assistance lessons with the learner. Prior to and after the program, the participants filled in an evaluation scale of functional social skills with which they defined the learner's management level of individual social skills. This helped acquire data on the social skills that the learner needs most assistance with. It also enabled recording changes in their management when the program was finished. The class cohesion was measured before and after the program using a sociometric method based on a two-dimensional sociometric classification system with limited choice sets. The test helped acquire information on the cohesion among learners (cohesion index), and the position of the learner with Asperger syndrome in the class (social status). The program encompassed 15 weekly meetings in the classroom and was based on targeted teaching of those social skills that the learner with Asperger syndrome needs most assistance with. The research was carried out on the basis of the social activities that proved to be effective for children with Asperger syndrome in the past by means of various approaches. At the end of the program, the assessors participated in an interview regarding any changes observed in the learner, and in the class (class teacher). The data obtained was statistically processed, and the results are presented with graphs and tables on the basis of hypotheses. A certain level of effectiveness was then attributed to the implemented program based on the results; however, it is impossible to determine that the program is unambiguously effective because this would imply that the social skills examined in this case were generalized to other settings. At the end of the program, positive changes were observed in the learner with Asperger syndrome in certain areas of social skills, and were marked on the scale by her parents and the special education teacher. In addition, the class teacher reported changes in social skills both in the student with Asperger syndrome and in her classmates. The class teacher also reported positive changes in the group dynamics, cooperation among learners, and their cohesion. The research has shown that introducing targeted teaching of social skills in class is sensible both for children with disabilities as well as for their peers. The program enables acquiring skills in a peer environment that is also the environment in which the acquired skills will be used. In addition, the program is also effective for children without major problems in social skills because their participation gives them insight into classmates who do face these problems. In the future, these children can regulate their functioning in such a way that they are more tolerant and understanding toward their classmates with problems in social skills
AMČR - projekt C-202411526
No full textStav: 6Podnět: Lipec, p. č. 143; IV-12-6035794Označení projektu: 1259/2024Označení stavby: IV-12-603579
AMČR - archeologický záznam C-9125300A
No full textStav: 3Lokalizace/okolnosti: U lesa "Lipec" nad obcí
AMČR - archeologický záznam C-202411526A
No full textStav: 3Označení: 1259/2024Lokalizace/okolnosti: Západní okraj obce. Parc.č.: 435/1. Lipec, č.parc. 143, IV-12-6035794.Souhrn/upřesnění: Rýha od sloupu VN k přípojce byla dlouhá jen 1 m. Akce tedy nebyla archeologem dohlížena osobně. V těchto místech ostatně z dohledů vodovodu v letech 2023-2024 nebyly zjištěny žádné archeologické situace
Synthesis and Structural Evaluation of Organo-Ruthenium Complexes with β-Diketonates
No full textFour novel ruthenium organometallic complexes: [(η6-p-cymene)Ru(4,4,4-trifluoro-1-(4-bromophenyl)-1,3-butanedione)Cl] (1), [(η6-p-cymene)Ru(4,4,4-trifluoro-1-(4-bromophenyl)-1,3-butanedione)pta]PF6 (2), [(η6-p-cymene)Ru(4,4,4-trifluoro-1-(4-iodophenyl)-1,3-butanedione)Cl] (3) and [(η6-p-cymene)Ru(4,4,4-trifluoro-1-(4-iodophenyl)-1,3-butanedione)pta]PF6 (4) were synthesized and characterized by elemental analysis, infrared (IR), UV-Vis, NMR and mass spectroscopy and single-crystal X-ray diffraction. The crystal structures and spectroscopic data were compared to the previously published complexes [(η6-p-cymene)Ru(4,4,4-trifluoro-1-(4-chloro-phenyl)-1,3-butanedione)Cl] (5) and [(η6-p-cymene)Ru(4,4,4-trifluoro-1-(4-chlorophenyl)-1,3-butanedione)pta]PF6 (6). The pairs of complexes 1 and 3 as well as 2 and 4 are isostructural, with the former crystallizing in triclinic P-1 and the latter in monoclinic P21/c. The ruthenium(II) ion is found in a pseudo-octahedral “piano-stool” geometry in all compounds. Bond lengths and angles are consistent with other complexes of this type. Complexes 2 and 4 exhibit some moderate dynamic disorder. The lack of hydrogen bonding and major π-π interactions means that most of intramolecular interactions are fairly weak and involve halogen atoms present. This was further confirmed by 1H-NMR spectra, where a significant difference is observed only on the ligand near the halogen atom, following an expected trend. The combined data show that the difference in any activity depends substantially on the type of the ligand′s substituted halogen atom
Synthesis and structural evaluation of organo-ruthenium complexes with ß-diketonates
No full textFour novel ruthenium organometallic complexes: [(η-p-cymene)Ru(4,4,4-trifluoro-1-(4-bromophenyl)-1,3-butanedione)Cl] (1), [(η-p-cymene)Ru(4,4,4-trifluoro-1-(4-bromophenyl)-1,3-butanedione)pta]PF (2), [(η-p-cymene)Ru(4,4,4-trifluoro-1-(4-iodophenyl)-1,3-butanedione)Cl] (3) and [(η-p-cymene)Ru(4,4,4-trifluoro-1-(4-iodophenyl)-1,3-butanedione)pta]PF (4) were synthesized and characterized by elemental analysis, infrared (IR), UV-Vis, NMR and mass spectroscopy and single-crystal X-ray diffraction. The crystal structures and spectroscopic data were compared to the previously published complexes [(η-p-cymene)Ru(4,4,4-trifluoro-1-(4-chloro-phenyl)-1,3-butanedione)Cl] (5) and [(η-p-cymene)Ru(4,4,4-trifluoro-1-(4-chlorophenyl)-1,3-butanedione)pta]PF (6). The pairs of complexes 1 and 3 as well as 2 and 4 are isostructural, with the former crystallizing in triclinic P-1 and the latter in monoclinic P2/c. The ruthenium(II) ion is found in a pseudo-octahedral “piano-stool” geometry in all compounds. Bond lengths and angles are consistent with other complexes of this type. Complexes 2 and 4 exhibit some moderate dynamic disorder. The lack of hydrogen bonding and major π-π interactions means that most of intramolecular interactions are fairly weak and involve halogen atoms present. This was further confirmed by H-NMR spectra, where a significant difference is observed only on the ligand near the halogen atom, following an expected trend. The combined data show that the difference in any activity depends substantially on the type of the ligand′s substituted halogen atom
Single cell atlas identifies lipid-processing and immunomodulatory endothelial cells in healthy and malignant breast
No full textSince a detailed inventory of endothelial cell (EC) heterogeneity in breast cancer (BC) is lacking, here we perform single cell RNA-sequencing of 26,515 cells (including 8433 ECs) from 9 BC patients and compare them to published EC taxonomies from lung tumors. Angiogenic ECs are phenotypically similar, while other EC subtypes are different. Predictive interactome analysis reveals known but also previously unreported receptor-ligand interactions between ECs and immune cells, suggesting an involvement of breast EC subtypes in immune responses. We also identify a capillary EC subtype (LIPEC (Lipid Processing EC)), which expresses genes involved in lipid processing that are regulated by PPAR-γ and is more abundant in peri-tumoral breast tissue. Retrospective analysis of 4648 BC patients reveals that treatment with metformin (an indirect PPAR-γ signaling activator) provides long-lasting clinical benefit and is positively associated with LIPEC abundance. Our findings warrant further exploration of this LIPEC/PPAR-γ link for BC treatment.sponsorship: We acknowledge A. Carton, A. Manderveld, K. Peeters, S. Wyns, N. Conchinha, J. Ardui, A. Ryckx, N. Willers and M. Parys for technical assistance. We also gratefully acknowledge the advice of B. Thienpont, A. Laenen and J. Goveia (Unicle). This studywas financially supported by: Strategisch Basisonderzoek FWO-Vlaanderen (V.G.); Marie Curie-IEF Fellowship (J.A.); `Fonds voor Wetenschappelijk Onderzoe L.d.R., J.A., A.-C.K.T., K.R., F.R.); University of Antwerp (L.-A.T.); Kom op Tegen Kanker (S.K.); the Luxemburg Cancer Foundation (FC/2018/07; C.D., E.I., F.R.); Belgian Cancer Foundation (FAF-C/2018/130; C.D., M.D.S.); AIAS-CO-FUND II: GA: MSCA:754513 (J.K.); Lundbeckfonden (R307-2018-3667; J.K.); Carlsberg Fonden (CF19-0687; J.K.); Kraeftens Bekaempelse (R302-A17296; J.K.); A.P. Moller Fonden (20-L-0317; J.K.); Riisfort Fonden and Steno Diabetes Center Aarhus (SDCA; J.K.); postdoctoral mandate from the Klinische onderzoeks-en opleidingsraad (KOOR) of the University Hospitals Leuven (G.F.); Sanming Project of Medicine in Shenzhen (SZSM201612074; Y.L.), BGI-Research (Y.L.), the Danish Research Council for Independent Research (DFF-1337-00128; Y.L.); the Sapere Aude Young Research Talent Prize (DFF-1335-00763A; Y.L.); Aarhus University Research Foundation (AU-iCRISPR; Y.L.); the State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China (X.L.); Program of Guangzhou Scientific Research Plan (202102010179; X.L.); the National Natural Science Foundation of China (82150710555; X.L.); Long-term structural Methusalem funding from the Flemish Government (M.M., P.C.); FWO (P.C.); Foundation against Cancer (2016-078; P.C.); Kom op Tegen Kanker (P.C.); ERC Proof of Concept (ERC-713758; P.C.) and ERC Advanced Research Grant (EU-ERC743074; P.C.).k' (FWO; (Strategisch Basisonderzoek FWO-Vlaanderen, Marie Curie-IEF Fellowship, Fonds voor Wetenschappelijk Onderzoe, University of Antwerp, Kom op Tegen Kanker, Luxemburg Cancer Foundation|FC/2018/07, Belgian Cancer Foundation|FAF-C/2018/130, AIAS-CO-FUND II: GA: MSCA|754513, Lundbeckfonden|R307-2018-3667, Carlsberg Fonden|CF19-0687, Kraeftens Bekaempelse|R302-A17296, A.P. Moller Fonden|20-L-0317, Riisfort Fonden, Klinische onderzoeks-en opleidingsraad (KOOR) of the University Hospitals Leuven, Sanming Project of Medicine in Shenzhen|SZSM201612074, Danish Research Council for Independent Research|DFF-1337-00128, Sapere Aude Young Research Talent Prize|DFF-1335-00763A, Aarhus University Research Foundation (AU-iCRISPR), State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China, BGI-Research, Program of Guangzhou Scientific Research Plan|202102010179, National Natural Science Foundation of China|82150710555, Flemish Government, Foundation against Cancer|2016-078, ERC Proof of Concept|ERC-713758, ERC Advanced Research Grant|EU-ERC743074, Steno Diabetes Center Aarhus (SDCA))status: Publishe
