1,720,960 research outputs found
Recurrent vitreous haemorrhage from sporadic retinal astrocytic hamartoma.
No full textThis paper describes the case of a 25-year-old white male presented in 2005 as an emergency with floaters and decreased visual acuity in the right eye who had recurrent vitreous hemorrhage. His past ocular history was positive for unexplained juxtapapillary retinal oedema and vitreous haemorrhage in 1996 with spontaneous resolution. Systemic and family history was negative. Fundus examination showed a circumscribed yellow white juxtapapillary retinal lesion along the superotemporal arcade with vitreous haemorrhage arising from the lesion. Our final diagnosis was sporadic retinal epipapillary astrocytic hamartoma with recurrent vitreous haemorrhage. Vitreous haemorrhage in retinal astrocytic hamartoma is unusual and has been reported previously only in the context of tuberous sclerosis. Our case suggests a vascular component exists in sporadic retinal astrocytic hamartoma. Retinal astrocytic hamartomas of tuberous sclerosis have been classified into three types by angiographic features: all three types block choroidal fluorescence to some extent and show late leakage on FA, but on ICG type 1 has subtle blockage of choroidal fluorescence, type 2 has total blockage (from calcification) and type 3 has total blockage only in the centre. Though our case is sporadic, it has features of type 1 on FA and type 2 on ICG, suggesting incomplete calcification. OCT features are also consistent with retinal astrocytic hamartoma. We believe that sporadic retinal astrocytic hamartoma should now be included in the differential diagnosis of recurrent vitreous haemorrhage – sporadic cases can exhibit vasculopathic features
Vasocentric fascicular uveal melanoma. Incidence and re-appraisal of the histological features
No full text[No abstract available
EFFICACIA E SICUREZZA DELLA COMBINAZIONE TIMOLOLO-DORZOLAMIDE VERSO LA CONCOMITANTE SOMMINISTRAZIONE DEI SINGOLI COMPONENTI
No full textGli autori descrivono i favorevoli risultati ottenuti con la combinazione timololo 0.50%-dorzolamide 2%, somministrata due volte al giorno, in un gruppo di 89 occhi affetti da GAA. Il protocollo di studio ha compreso tre diversi periodi di osservazione della durata di tre mesi: l) terapia a base di solo timololo 0.50%, due volte al giorno: 2) associazione al timololo 0.50% di dorzolamide 2%, due volte al giorno; 3) instillazione della combinazione fissa timololo-dorzolamide, due volte al giorno.
In base ai dati ottenuti, si è osservato che la combinazione fissa dei due principi attivi ha consentito di mantenere la riduzione della IOP ottenuta con la somministrazione dei due farmaci associati. Gli effetti collaterali locali e quelli sistemici, rispettivamente del 6,66% e del 4.44%, si sono evidenziati solo con la combinazione dei due farmaci.
Si ritiene che tale combinazione possa rappresentare una valida alternativa terapeutica nel trattamento del GAA che consente di facilitare la compliance, riducendo il numero delle instillazioni giornaliere con conseguente miglioramento della qualità di vita dei pazienti
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
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