8,380 research outputs found
Howell‐Jolly body counting as a measure of splenic function. A reassessment
Summary Non‐surgical and surgical asplenia predisposes to fatal infections; therefore, simple, non‐invasive and repeatable tests for assessing splenic function are required, even in non‐specialized medical institutions. Howell‐Jolly bodies are the most characteristic peripheral blood abnormality after splenectomy, but their counting is not considered a reliable measure of splenic function. In this study, in a group of splenectomized subjects and of patients with non‐surgical hyposplenism, we have compared counting of Howell‐Jolly bodies, stained by both the May‐Grünwald/Giemsa method and the Feulgen reaction, with pitted cell counting which is considered a reliable technique for the assessment of splenic hypofunction. A significant correlation has been found between Howell‐Jolly body counts, stained by either technique, and pitted cell counts (P < 0.0001). Though Howell‐Jolly bodies were never detectable when pitted cell counts fell between 4 and 8%, values consistent with a very mild splenic hypofunction, for pitted cell counts above 8% their increase was always associated with increasing Howell‐Jolly body counts. These data suggest that, although pitted cell counting represents a more sensitive method for evaluating splenic function, Howell‐Jolly body counting may still be regarded as a simple and reliable technique for identifying and monitoring those cases associated with a real risk of overwhelming infections. Copyright © 1990, Wiley Blackwell. All rights reserve
View of an old mill at Parramatta, New South Wales [picture] /
Plate on p. 24 of: Australian picture pleasure book /Walter G. Mason; Print depict's Howell's Mill at Parramatta built by George Howell and featured both a watermill and a windmill.; Rex Nan Kivell Collection NK2106/60; U776; S1290
On the modeling of a contact-aided cross-axis flexural pivot
This paper reports the study of a planar Cross-Axis Flexural Pivot (CAFP) comprising an additional contact pair. The proposed device may be useful for applications requiring a revolute joint that behaves differently when deflecting clockwise/anti-clockwise. The presence of the contact pair reduces the free length of one flexures, resulting in a considerable increment of the overall joint stiffness. The pivot behaviour is investigated, for different load cases, via the Chained-Beam-Constraint Model (CBCM), namely an accurate method to be applied in large deflection problems. A framework comprising Matlab and ANSYS is developed for testing the CAFP performances in terms of rotational stiffness, parasitic shift and maximum stress, with different combinations of geometrical aspect ratios and contact extensions. Results achieved via CBCM for a pure rotation applied to the CAFP's output link are then verified through Finite Element Analysis. The resulting performance maps show good agreement between the numerical results. Furthermore, the CBCM shows an improved computational efficiency, which is a crucial aspect for preliminary design steps. At last, direct comparison between simulations and experiments, developed by means of two custom test rigs, confirms the efficacy of the proposed design method for the modeling of contacts in large deflection problems
Howell, S. N. G. & Schmitt, F.— Birds of Chile. A photo guide. Princeton University Press, Princeton & Oxford. 2018
Érard Chr. Howell, S. N. G. & Schmitt, F.— Birds of Chile. A photo guide. Princeton University Press, Princeton & Oxford. 2018. In: Revue d'Écologie (La Terre et La Vie), tome 73, n°4, 2018. p. 621
appendix – Supplemental material for Financial Incentives in Vertical Diffusion: The Variable Effects of Obama’s Race to the Top Initiative on State Policy Making
Supplemental material, appendix for Financial Incentives in Vertical Diffusion: The Variable Effects of Obama’s Race to the Top Initiative on State Policy Making by William G. Howell and Asya Magazinnik in State Politics & Policy Quarterly</p
Postveraison application of antitranspirant Di-1-p-Menthene to control sugar accumulation in Sangiovese grapevines
The effectiveness of a postveraison application of the film-forming antitranspirant Vapor Gard (VG, a.i. di-1-p-menthene) was investigated as a technique to delay grape ripening and reduce sugar accumulation in the berry. The study was carried out over the 2010-2011 seasons in a nonirrigated vineyard of cv. Sangiovese in central Italy. Vapor Gard was applied at 2% concentration to the upper two-thirds of the canopy (most functional leaves) and it significantly lowered leaf assimilation and transpiration rates and increased intrinsic water use efficiency. The Fv/Fmratio was not modified, emphasizing that photoinhibition did not occur at the photosystem II complex, whereas the reduction of pool size of plastoquinone matched well with reduced CO2fixation found in VG-treated vines. In both years VG treatment reduced the pace of sugar accumulation in the berry as compared to control vines, scoring a -1.2 Brix at harvest and wine alcohol content at -1% without compromising the recovery of concentrations of carbohydrates and total nitrogen in canes and roots. Concurrently, organic acids, pH, and phenolic richness of grapes and wines were unaffected, whereas there was a decrease in anthocyanin content in the berry (-19% compared to control vines) and in the wine (-15% compared to control vines). The application of VG at postveraison above the cluster zone is an effective, simple, and viable technique to hinder berry sugaring and obtain less alcoholic wines. To be effective the spraying should be performed at ~14 to 15 Brix, making sure that the lower leaf epidermis is fully wetted by the chemical
Postveraison application of antitranspirant di-1-p-menthene to control sugar accumulation in sangiovese grapevines
The effectiveness of a postveraison application of the film-forming antitranspirant Vapor Gard (VG, a.i. di-1-p-menthene) was investigated as a technique to delay grape ripening and reduce sugar accumulation in the berry. The study was carried out over the 2010-2011 seasons in a nonirrigated vineyard of cv. Sangiovese in central Italy. Vapor Gard was applied at 2% concentration to the upper two-thirds of the canopy (most functional leaves) and it significantly lowered leaf assimilation and transpiration rates and increased intrinsic water use efficiency. The Fv/Fmratio was not modified, emphasizing that photoinhibition did not occur at the photosystem II complex, whereas the reduction of pool size of plastoquinone matched well with reduced CO2fixation found in VG-treated vines. In both years VG treatment reduced the pace of sugar accumulation in the berry as compared to control vines, scoring a -1.2 Brix at harvest and wine alcohol content at -1% without compromising the recovery of concentrations of carbohydrates and total nitrogen in canes and roots. Concurrently, organic acids, pH, and phenolic richness of grapes and wines were unaffected, whereas there was a decrease in anthocyanin content in the berry (-19% compared to control vines) and in the wine (-15% compared to control vines). The application of VG at postveraison above the cluster zone is an effective, simple, and viable technique to hinder berry sugaring and obtain less alcoholic wines. To be effective the spraying should be performed at ~14 to 15 Brix, making sure that the lower leaf epidermis is fully wetted by the chemical
Zero torque compliant mechanisms employing pre-buckled beams
The concept of a statically balanced mechanism with a single rotational degree-of-freedom is presented. The proposed device achieves static balancing by combining positive stiffness elements and negative stiffness elements within an annular domain. Two designs are discussed. The first is composed of an Archimedean spiral and two pinned-pinned pre-buckled beams. The overall mechanism is modeled via an analytical approach and the element dimensions are optimized. The optimal configuration is then tested through finite element analysis (FEA). A second approach replaces the spiral beam with elastic custom-shaped spline beams. A FEA optimization is performed to determine the shape and size of such spline beams. The behavior of the negators is used as reference for the optimization so as to achieve a complete balancing. A physical prototype of each configuration is machined and tested. The comparison between predicted and acquired data confirmed the efficacy of the design methods
Notice to David Meriwether from Howell Cobb
Notice dated February 9, 1857 from Howell Cobb, Secretary of the Treasury, Washington, D.C., to David Meriwether, Governor of New Mexico, acknowledging receipt of Meriwether's letter transmitting his account, as Disbursing Agent, for the month of November, for the penitentiary being constructed at Santa Fe, New Mexico. Notice signed by P. G. Washington for the Secretary. HL introduction page overlaid by document. Notice in English, handwritten, 1pp/fr
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