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    Rare-earth elements abundance in tissues and plasma of healthy subjects and patients by neutron activation analysis

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    In recent years much attention has been paid to the presence and role played by trace metals in human tissues and body fluids. Rare-earth element ions are known to have high affinity for calcium binding sites and to antagonize calcium-mediate biological response. The present paper describes an investigation on rare-earth elements abundance in tissue and endogenous plasma of apparently healthy subjects and patients affected by epicondylitis, at the elbow or by laryngeal carcinoma. Some rare-earth elements, namely La, Ce, Nd, Eu, Gd, Yb and Lu, were determined by radiochemical neutron activation analysis. Results are presented and discussed as far as precision, accuracy and sensitivity are concerned. The obtained data indicate that rare-earth elements levels in plasma and tissues are significantly affected by the occurence of pathological condition

    Platinum assay by neutron activation analysis and atomic absorption spectroscopy in cisplatin treated pregnant CD-1 mice

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    Cisplatin (CDDP) is an antineoplastic drug used in the treatment of a wide variety of tumors. This paper describes an investigation carried out on pregnant mice after intragastric or intraperitone-ally treatment with CDDP from day 11 to 13 of gestation. Platinum content in different tissues, namely liver, kidney, placenta and brain, was determined at 18 day of pregnancy. Two analytical techniques were used, i.e. neutron activation analysis and atomic absorption spectroscopy. Results of both techniques are presented and discussed in terms of precision, accuracy and sensitivity. Neutron activation analysis appears to provide results better correlated with the drug treatmen

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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