549 research outputs found
Supplemental Material - The Use of <i>In Silico</i> Methods to Identify and Assess Antigenic Regions Suitable for the Development of Peptide-based Pan-viral Vaccines
Supplemental Material for The Use of In Silico Methods to Identify and Assess Antigenic Regions Suitable for the Development of Peptide-Based Pan-Viral Vaccines by Shayana Saravanakumar and Jhinuk Chatterjee in Alternatives to Laboratory Animals</p
sj-docx-1-pie-10.1177_09544089221134446 - Supplemental material for Optimisation of underwater friction stir welding parameters of aluminum alloy AA5083 using RSM and GRA
Supplemental material, sj-docx-1-pie-10.1177_09544089221134446 for Optimisation of underwater friction stir welding parameters of aluminum alloy AA5083 using RSM and GRA by R Saravanakumar, T Rajasekaran and C Pandey in Proceedings of the Institution of Mechanical Engineers, Part E: Journal of Process Mechanical Engineering</p
Stability of markovian jump generalized neural networks with interval time-varying delays
This paper examines the problem of asymptotic stability for Markovian jump generalized neural networks with interval time-varying delays. Markovian jump parameters are modeled as a continuous-time and finite-state Markov chain. By constructing a suitable Lyapunov-Krasovskii functional (LKF) and using the linear matrix inequality (LMI) formulation, new delay-dependent stability conditions are established to ascertain the mean-square asymptotic stability result of the equilibrium point. The reciprocally convex combination technique, Jensen's inequality, and the Wirtinger-based double integral inequality are used to handle single and double integral terms in the time derivative of the LKF. The developed results are represented by the LMI. The effectiveness and advantages of the new design method are explained using five numerical examples
Use of Mask in Girish Karnad’s Play Tughlaq
Girish Karnad is a multiple personality- a regional, national and international playwright, actor, film-maker and director. His plays have been performed all over the world and translated into many languages. For his works, Karnads has received a number of awards including “Gnanapeeth Award.” In Indian folk theatres, half-curtain is used to introduce a character. It shows a well as hides the face of the character. Mask is also used either to conceal or reveal a character’s reality. So the paper’s aims to study the use of a mask in Girish Karnad’s play “Tughlaq.” Tughlaq is the most complex and complicated of Girish Karnad’s works. This play is about the rash actions of Tughlaq which finally lead to his downfall. His followers fail to grasp his idealism with the result that they become his enemies. There is a faint comparison between Tughlaq and Nehru, as the idealism of the two leaders created only confusion and topsy-turvydom.
Article DOI : 10.5958/2347-6869.2017.00002.
EDS microanalysis of blast furnace slag grains in aged concrete
The chemistry of ground granulated blast furnace slag (GGBFS) is one of the main factors affecting its reactivity. Knowing the composition of GGBFS used in aged concrete may help understand its past performance and estimate remaining service life. It is well known that GGBFS generally react slower than cement clinker. This thesis proposes that partially hydrated GGBFS grains found in aged concrete could be used to determine its chemical composition. The feasibility of using standard-based energy dispersive X-ray spectroscopy (EDS) microanalysis, along with electron imaging, as a tool for quantitative measurement of the chemical composition of GGBFS grains in cement/concrete is explored in this research. X-ray spectra collected from minerals or glasses of known composition are known as standards for quantitative EDS microanalysis. This study initially examined the performance of mineral and slag standards to quantify X-ray spectra obtained from GGBFS-cement paste specimens of known composition. Parameters such as GGBFS properties, experimental conditions, and microanalysis methodologies that affect the EDS quantitative total and accuracy were elaborated. Then, the same standards were used to quantify the unknown composition of GGBFS used in seven concrete specimens collected in the Netherlands representing different service life, which revealed the variation in GGBFS chemistry over the years. Finally, as a supplementary study, the variation in significant hydration products formed due to variation in GGBFS composition in a cement-GGBFS system was predicted using thermodynamic modelling with GEMS. Altogether, it was concluded that standard-based EDS is a solid tool to characterize the chemical composition of GGBFS used in aged concrete.Civil Engineerin
A Cross Sectional study on the Prevalence of Exclusive Breastfeeding Practices among the Irular Mothers in Thiruvallur District, Tamilnadu, 2011.
BACKGROUND : Exclusive breastfeeding, which means to give only breast milk to the
infant till first six months, is the ideal way for the healthy growth and development.
Globally 53% of the under-five deaths are due to under-nutrition. Exclusive
breastfeeding prevents the under-nutrition, diarrhoea and Pneumonia. But the
prevalence of exclusive breastfeeding is low globally (35%) and nationally (46.4%).
In India, the prevalence of exclusive breastfeeding is not only low among the general
population but also among the tribes, where malnutrition is highly prevalent, which
needs to be explored. OBJECTIVES : To assess the prevalence of Exclusive breastfeeding
practice and the factors influencing it among the Irulars in Thiruvallur District, one of
the primitive tribes in Tamil Nadu. METHODOLOGY : This community based crosssectional study was conducted among the Irular mothers with children of age 6 to 24
months residing in the tribal villages in six Taluks of the Thiruvallur District, Tamil
Nadu between March 2011 to November 2011. The sample size was 375 based on
DLHS3 2007-08. Data was collected by simple random sampling using the pretested,
standardized Tamil questionnaire and was analyzed using Chi Square and Fisher’s
Exact test. RESULTS : The prevalence of Exclusive breastfeeding among the Irulars is
26.9% with the median duration as 5 months. Only 35.2% of the mothers gave
colostrum as the first feed while 64.8% gave prelacteal feeds, of whom 73% had
discarded the colostrum. The important reasons for non-exclusive breastfeeding were
the lack of support from the family and fear of inadequate milk. Increasing maternal
age, age at conception, Education, antenatal counseling on breastfeeding, awareness,
previous breastfeeding experience and postnatal support from the health workers were
the factors favouring the Exclusive breastfeeding with statistical significance
(p<0.05). Conclusions: Health Education, antenatal counseling of the Irular mothers,
encouraging to give colostrum within the first hour of life, Exclusive breastfeeding up
to six months of age, avoiding the traditional beliefs like prelacteal feeds, discarding
the colostrum and training the health workers to promote exclusive breastfeeding are
the vital measures against the under-nutrition, morbidity and infant mortality
Antimycobacterial activity of the red algae gelidium pristoides, plocamium corallorhiza and polysiphonia virgata
Summary in English.In 1993, the World Health Organisation declared tuberculosis a global health emergency. Currently, efforts are underway to improve the way the disease is managed and to find more effective treatments that would combat the problem of long treatment periods, toxicity, drug-resistance and HIV-coinfection. In the process, natural product chemistry continues to play an important role in the search for new compounds to treat tuberculosis. Terrestrial plants have been investigated for antimycobacterial activity, while marine plants are yet to receive as much attention. In this project, three South African marine plants were drawn into the search for novel anti-tuberculosis compounds. One of the seaweeds is already part of the local seaweed industry, namely Gelidium pristoides, while Plocamium corallorhiza and Polysiphonia virgata have economic potential. These three red algae were extracted extensively and fractionated using preparative layer chromatography and preparative centrifugally accelerated radial thin-layer chromatography (Chromatotron). The crude extracts of the algae showed no inhibitory activity to growth of the causative agent of human tuberculosis, Mycobacterium tuberculosis. However, when the purified fractions were tested against M. tuberculosis in the BACTEC-460 radiometric method at a concentration of 125 μg/mL, fractions 322, 323 and 333 of P. virgata showed 100% inhibition, while two fractions of G. pristoides showed 91.7% and 79.2% inhibition, respectively. Two fractions of P. corallorhiza demonstrated 41.2% and 73.5% inhibition. The bioactive fractions of P. virgata were further purified and resulted in the isolation of a known compound namely, 2-methoxyethyl-2-methacrylate (MEMA). When MEMA was tested by radiometric assay against M. tuberculosis, it showed anti-tuberculosis activity at a MIC-value of 100 μg/mL and no cytotoxicity against Chinese hamster ovarian cells. However, in a re-investigation into the bioactive compounds of P. virgata it was established that MEMA was not the major bioactive compound. Long chain fatty acids were responsible for the antimycobacterial activity of the algal extract particularly oleic acid, linoleic acid, dodecanoic acid, and myristic acid. Oleic acid inhibited the growth of M. tuberculosis at and MIC-value of 25 11 g/rnL, while dodecanoic acid, myristic acid and linoleic acid all had MIC-values of 50 μg/mL. Stearic acid and palmitic acid was also isolated from the seaweed, but only moderate inhibition of M. tuberculosis was observed for at MIC-values of 50 μg/mL. Oleic acid showed moderate inhibition at 50 μg/mL against the multi-drug resistant isolate of M. tuberculosis, while myristic acid and dodecanoic acid showed significant inhibition against the same at 50 μg/mL and moderate inhibition at 25 μg/mL. Linoleic acid also inhibited the growth of the multi-drug resistant strain at 50 μg/mL. Oleic acid showed the most inhibition of the growth of M. smegmatis in direct bioautography with an MIC-value of 0.8 μg/mL, while linoleic acid and dodecanoic acid had MIC-values of 1.56 μg/mL and 3.125 μg/mL., respectively. Stearic acid, palmitic acid, and myristic acid did not inhibit the growth of M. smegmatis
P-order e-open Continuous Mapping in Cubic Topological Spaces
we discuss about nearby open sets, their properties and examples of it. Moreover, we look into some of their primary properties and examples of P-cubic e-continuous in a P order cubic topological space
EDS Microanalysis of Unhydrated Blast Furnace Slag Grains in Field Concrete with Different Service Life
Because the essential quality metrics of blast furnace slag are based on its oxide composition, the determination of chemical compositions of unhydrated slag grains in an aged concrete could be useful for understanding its past performance and in predicting the remaining service life of existing slag-bearing concrete. In this research, the authors explored the feasibility of using standard-based energy-dispersive X-ray spectroscopy (EDS) microanalysis, in tandem with electron imaging, as a tool for quantitative measurement of the chemical composition of blast furnace slag grains in cement/concrete. In the experimental study, seven concrete samples representing various service life durations were collected in the Netherlands. The microanalysis results of the samples revealed that the change in slag chemistry is insignificant for samples B (1985) to F (2006); however, elevated CaO and SiO2 contents are found in slag used for sample G (2015), opposite to that of Al2O3 and MgO. After discussing compositional characterization, the paper discusses favorable microanalysis protocols for acceptable elemental quantification accuracy. It was concluded that quantitative EDS microanalysis is a strong tool to characterize the chemical composition of unhydrated slag used in field concrete, which could potentially contribute to understanding the correlations between composition and long-term performance in slag concrete structures. Materials and Environmen
WITHDRAWN: Analytical solution of an amperometric biosensor based on catalase-peroxidase biochemical reactions using Homotopy perturbation method
This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy
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