83 research outputs found
Teaching Field Broadens in Scope
Get PDFIowa schools have a greater need for homemaking teachers due to the war, says Norma Shellito</p
PUBLISHED VERSION
No full textOates, J.; Shellito, P. Phase II study of capecitabine and mitomycin C as first-line treatment in patients with advanced colorecta
Longitudinal quality of life and quality adjusted survival in a randomised controlled trial comparing six months of bolus fluorouracil/leucovorin vs. twelve weeks of protracted venous infusion fluorouracil as adjuvant chemotherapy for colorectal cancer
No full textLongitudinal quality of life (QOL) assessment is infrequently made in adjuvant therapy for colorectal cancer (CRC). This analysis aims to assess QOL and quality adjusted survival (QAS) in patients receiving adjuvant 5-FU for stage II and III CRC. We performed a multicentre study in which 801 patients were randomised to 6 months of bolus 5-FU/leucovorin (LV n = 404) or 12 weeks of protracted venous infusion (PVI) 5-FU (n = 397). There were significant differences in the deterioration of QOL scores at week 2 with bolus 5-FU/LV compared to PVI 5-FU (P < 0.001), coinciding with toxicity peak during the first cycle. Following week 12, global QOL recovered to baseline when PVI 5-FU was stopped but this was delayed with bolus 5-FU/LV until completion at week 24. QOL scores significantly improved in both arms during follow-up (P < 0.001) and reached a plateau by year 1 without incremental improvement between years 2 and 5. There was a trend towards better QAS with PVI 5-FU. Twelve weeks of adjuvant PVI 5-FU was associated with significantly better QOL during treatment and faster time to recovery compared to 6 months of bolus 5-FU/LV. <br/
The Iowa Homemaker vol.23, no.10
No full textKeeping Up With Today, Marilyn Clayton, page 2
Victory Canning Corps, Corinne Cunningham, page 3
Posters for South America, Frances Kerekes, page 4
Choosing Your College, Clara M. Brown, page 5
For Random Reading, Lila Mae Hummel, page 7
Wanted: More Home Economics, Victoria McKibben, page 9
Teaching Field Broadens in Scope, Norma Shellito, page 10
Food Customs from the Phillipines, Soledad Payawal, page 11
Sheer Simplicity, Josephine Ahern, page 12
Association Benefits Graduates, Zoe Wilson, page 14
Forecasting Textile Supply, Elizabeth Peterson, page 15
What’s New in Home Economics, Mildred Krogh, page 16
Packaging for Post War Foods, Virginia Carter, page 18
Challenge from Latin America, Delores Stewart, page 19
Designed for Individuality, Gertrude Richards, page 21
More Products from Plastics, Mary Elizabeth Lush, page 23
Fashions in Weeds, Marilyn Baker, page 24
Across Alumnae Desks, Harriet Keen, page 26
Rehabilitation Challenges Home Economist, Marian Hoppe, page 28
Alums in the News, Patricia Maddex, page 30
Electronics Change Food Flavors, Barbara Reader, page 32</p
Controls on surface soil drying rates observed by SMAP and simulated by the Noah land surface model
Get PDFDrydown periods that follow precipitation events provide an
opportunity to assess controls on soil evaporation on a continental scale. We
use SMAP (Soil Moisture Active Passive) observations and Noah simulations
from drydown periods to quantify the role of soil moisture, potential
evaporation, vegetation cover, and soil texture on soil drying rates. Rates
are determined using finite differences over intervals of 1 to 3 days. In the
Noah model, the drying rates are a good approximation of direct soil
evaporation rates, and our work suggests that SMAP-observed drying is also
predominantly affected by direct soil evaporation. Data cover the domain of
the North American Land Data Assimilation System Phase 2 and span the first
1.8 years of SMAP's operation.
Drying of surface soil moisture observed by SMAP is faster than that
simulated by Noah. SMAP drying is fastest when surface soil moisture levels
are high, potential evaporation is high, and when vegetation cover is low.
Soil texture plays a minor role in SMAP drying rates. Noah simulations show
similar responses to soil moisture and potential evaporation, but vegetation
has a minimal effect and soil texture has a much larger effect compared to
SMAP. When drying rates are normalized by potential evaporation, SMAP
observations and Noah simulations both show that increases in vegetation
cover lead to decreases in evaporative efficiency from the surface soil.
However, the magnitude of this effect simulated by Noah is much weaker than
that determined from SMAP observations
Working towards an ecosystem approach to North Atlantic marine aquaculture
No full text No abstracts are to be cited without prior reference to the author. Conveners: Gesche Krause (Germany), Jann Martinsohn (European Commission), Ryan B. Carnegie (USA).CM 2018/O:424. An ecosystem approach to seaweed aquaculture, a comparison of ecosystem goods and services. Richard Langton, Tammy Murphy, Lisa Milke, Thomas NojiCM 2018/O:571. Is aquaculture of the future full of gene-edited fish? eExperiences and perspectives from the CRISPR-Cas9 gene-edited sterile Norwegian salmon. Dorothy J. DankelCM 2018/O:622. Guidelines for seaweed aquaculture in Europe. : Araujo R, Abreu H, De Clerk O, Funderud J, Holdt S, Jacquemin B, Rebours C, Timmermans K, Charrier B, Barbier MCM 2018/O:155. Modelling the environmental impacts of future offshore fish farms in the inner Danish waters. Marie Maar, Janus Larsen, Karsten Dahl, Bo RiemannCM 2018/O:29. Fish efficiency; the missing part for the description of the total efficiency of fish feeding. Eckhard BethkeCM 2018/O:604. Understanding disease as a key biotic interaction between aquaculture and environment. Ryan B. CarnegieCM 2018/O:602. Kelp farming as a potential remediation strategy for coastal acidification. Nichole N. Price, Suzanne N. Arnold, Joe Salisbury, Paul Dobbins, Brittney Honisch, Christopher Hunt, Shawn Shellito, Melissa M.M. Oyola, Evangeline FachonCM 2018/O:105. Environmental impact assessment for aquaculture activities in the Macaronesia. Lydia Png-Gonzalez, Natacha Nogueira, Carlos AndradeCM 2018/O:611. Impact of global warming on diseases in aquaculture. Øivind Bergh, Lars Asplin, Nina Sandlund, Anne D. Sandvik, Sonal Patel, Joao G. Ferreira, Nick TaylorCM 2018/O:487. Using public comments to explore social licence to operate for aquaculture. Suzannah-Lynn BillingCM 2018/O:203. A heart for the Carp culture; the role of region-marketing to maintain traditional aquacultures in Europe. Tobias Lasner, Adam Mytlewski, Myriam Nourry, Marcin Rakowski, Martin OberleCM 2018/O:481. Combined nutrients effects from aquaculture and agriculture on macroalgal growth: a bioassay experiment. Michael D. Streicher, Katrin Reiss, Henning Reiss</p
Phase II study of capecitabine and mitomycin C as first-line treatment in patients with advanced colorectal cancer
Get PDFThis study was designed to assess the safety and efficacy of capecitabine and mitomycin C (MMC) in previously untreated patients with advanced colorectal cancer (CRC). Patients received capecitabine 2500 mg m2 day 1, orally divided in two doses of 1250 mg m-2 in the morning and evening for 14 days every 21 days and MMC 7 mg m-2 (maximum total dose 14 mg) as an intravenous bolus every 6 weeks for a total of four courses. The median age was 70 years (range 24–85) and the majority of patients (86.9%) were of performance status 1/2. The most common metastatic site was liver. In all, 84 patients were assessable for response. The overall response rate was 38% (95% CI: 27.7–49.3) and a further 33.3% of patients achieved stable disease over 12 weeks. There was good symptom resolution ranging from 64 to 86%. Grade 3/4 toxicity was as follows: hand–foot syndrome 19.7%; diarrhoea 10%; neutropenia 2.4%; infection 2.3%. Capecitabine and MMC have shown encouraging activity with a favourable toxicity profile, a convenient administration schedule, and could be considered for patients deemed unsuitable for oxaliplatin and irinotecan combinations.S Rao, D Cunningham, T Price, M E Hill, P J Ross, N Tebbutt, A R Norman, J Oates and P Shellit
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