405 research outputs found
High-entropy dual functions over finite fields and locally decodable codes
Get PDFWe show that for infinitely many primes p, there exist dual functions of order k over Fnp that cannot be approximated in L∞-distance by polynomial phase functions of degree k−1. This answers in the negative a natural finite-field analog of a problem of Frantzikinakis on L∞-approximations of dual functions over N (a.k.a. multiple correlation sequences) by nilsequences
Towards a decision support system for maintenance and reliability models using a multimedia based approach
No full textAge composition, growth, and reproduction of koi carp (Cyprinus carpio L.) in the lower Waikato, New Zealand
No full textA total of 566 koi carp (Cyprinus carpio) from the lower Waikato region were aged from scales and opercular bones, and growth was modelled with the von Bertalanffy growth function. There was no difference in growth rate between male and female carp. Growth of koi carp between zero and 3 years of age was lower than that of common carp in Europe and Australia. However, after 5 years of age the growth of koi carp was higher than that of common carp in Europe, but still below that of carp in Australia. Males rarely lived in excess of 8 years, whereas females lived to 12 years. Mean total fecundity calculated from 44 running-ripe females was 299 000 oocytes (±195 600 SD) (range 29 800–771 000). Relative fecundity ranged from 19 300 to 216 000 oocytes kg–1 total body weight, with a mean of 97 200 (±35 000 SD) oocytes kg–1. Feral koi carp in the Waikato are capable of multiple spawnings within their lifetimes. Within a spawning season, Waikato populations of feral koi carp contained females that spawned once, and females that had the potential to have spawned repeatedly. Female gonadosomatic index (GSI) varied with season and was negatively related to water temperature
Selection of new production facilities with the Group Analytic Hierarchy Process Ordering method
No full textsj-docx-1-cjk-10.1177_20543581241228723 – Supplemental material for Proton Pump Inhibitors Use in Kidney Transplant Recipients: A Population-Based Study
No full textSupplemental material, sj-docx-1-cjk-10.1177_20543581241228723 for Proton Pump Inhibitors Use in Kidney Transplant Recipients: A Population-Based Study by James Kiberd, Robert R. Quinn, Pietro Ravani, Krista L. Lentine, Alix Clarke, Rachel Jeong, Labib Faruque and Ngan N. Lam in Canadian Journal of Kidney Health and Disease</p
Cerium Oxide Nanoparticles (CeO2 NPs) Enhance Salt Tolerance in Spearmint (Mentha spicata L.) by Boosting the Antioxidant System and Increasing Essential Oil Composition
No full textSalinity represents a considerable environmental risk, exerting deleterious effects on horticultural crops. Nanotechnology has recently emerged as a promising avenue for enhancing plant tolerance to abiotic stress. Among nanoparticles, cerium oxide nanoparticles (CeO2 NPs) have been demonstrated to mitigate certain stress effects, including salinity. In the present study, the impact of CeO2 NPs (0, 25, and 100 mg L−1) on various morphological traits, photosynthetic pigments, biochemical parameters, and the essential oil profile of spearmint plants under moderate (50 mM NaCl) and severe (100 mM NaCl) salinity stress conditions was examined. As expected, salinity reduced morphological parameters, including plant height, number of leaves, fresh and dry weight of leaves and shoots, as well as photosynthetic pigments, in comparison to control. Conversely, it led to an increase in the content of proline, total phenols, malondialdehyde (MDA), hydrogen peroxide (H2O2), and antioxidant enzyme activities. In terms of CeO2 NP applications, they improved the salinity tolerance of spearmint plants by increasing chlorophyll and carotenoid content, enhancing antioxidant enzyme activities, and lowering MDA and H2O2 levels. However, CeO2 NPs at 100 mg L−1 had adverse effects on certain physiological parameters, highlighting the need for careful consideration of the applied concentration of CeO2 NPs. Considering the response of essential oil compounds, combination of salinity stress and CeO2 treatments led to an increase in the concentrations of L-menthone, pulegone, and 1,8-cineole, which are the predominant compounds in spearmint essential oil. In summary, foliar application of CeO2 NPs strengthened the resilience of spearmint plants against salinity stress, offering new insights into the potential use of CeO2 NP treatments to enhance crop stress tolerance
MCM-GINS and MCM-MCM interactions in vivo visualised by bimolecular fluorescence complementation in fission yeast
No full textBackground: Each of the three individual components of the CMG complex (Cdc45, MCM and GINS) is essential for chromosomal DNA replication in eukaryotic cells, both for the initiation of replication at origins and also for normal replication fork progression. The MCM complex is a DNA helicase that most likely functions as the catalytic core of the replicative helicase, unwinding the parental duplex DNA ahead of the moving replication fork, whereas Cdc45 and the GINS complex are believed to act as accessory factors for MCM. Results:To investigate interactions between components of the CMG complex, we have used bimolecular fluorescence complementation (BiFC) in the fission yeast Schizosaccharomyces pombe for the first time, to analyse protein-protein interactions between GINS and MCM subunits expressed from their native chromosomal loci. We demonstrate interactions between GINS andMCM in the nuclei of exponentially-growing fission yeast cells and on chromatin in binucleate S-phase cells. In addition we present evidence of MCM-MCM interactions in diploid fission yeast cells. As with GINS-MCM interactions, MCM-MCM interactions also occur on chromatin in S-phase cells. Conclusion: Bimolecular fluorescence complementation can be used in fission yeast to visualise interactions between two of the three components of the CMG complex, offering the prospect that this technique could in the future be used to allow studies on replication protein dynamics in living S. pombe cells.Peer reviewe
LBVS no decoys
No full textTwo datasets for Ligand-Based Virtual Screening (LBVS) benchmarking without decoys.
If you use them, please cite the original datasets:
@article{butkiewicz2013,
title={Benchmarking ligand-based virtual High-Throughput Screening
with the PubChem database},
author={Butkiewicz, Mariusz and Lowe, Edward W and Mueller, Ralf and
Mendenhall, Jeffrey L and Teixeira, Pedro L and
Weaver, C David and Meiler, Jens},
journal={Molecules},
volume={18},
number={1},
pages={735--756},
year={2013},
publisher={Multidisciplinary Digital Publishing Institute},
doi={10.3390/molecules18010735}
}
@article{Lagarde2014,
author = {Lagarde, Nathalie and Ben Nasr, Nesrine and Jérémie, Aurore and
Guillemain, Hélène and Laville, Vincent and Labib, Taoufik and
Zagury, Jean-François and Montes, Matthieu},
title = {NRLiSt BDB, the Manually Curated Nuclear Receptors Ligands and
Structures Benchmarking Database},
journal = {Journal of Medicinal Chemistry},
volume = {57},
number = {7},
pages = {3117-3125},
year = {2014},
doi = {10.1021/jm500132p},
note ={PMID: 24666037},
URL = {http://dx.doi.org/10.1021/jm500132p},
eprint = {http://dx.doi.org/10.1021/jm500132p}
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