170,606 research outputs found
Angiogenesis and hereditary hemorrhagic telangiectasia. Rendu-Osler-Weber disease
No full textTo date much of the recent work on pathological angiogenesis has focused on inflammatory diseases, diabetes and cancer in particular. Hereditary hemorrhagic telangiectasia or Rendu-Osler-Weber disease provides an example of the genetic disorder of angiogenesis in which a multisystemic angiodysplasia is responsible for severe hemorrhage. The disease pathogenesis is partially explained by a defect in the TGF-beta signaling system, although in more recent works a possible role of other vascular growth factors has been proposed. This paper provides a model of an aberrant angiogenesis in which multiple vascular growth factors could be involved in a diffuse angiodysplasia. Copyright (C) 2001 S. Karger AG, Basel
REACTIONS OF MAIZE INBRED LINES INFECTED WITH BARLEY YELLOW DWARF VIRUS IN NATURAL AND EXPERIMENTAL CONDITIONS
No full textBARLEY YELLOW DWARF VIRUS INFECTIONS IN MAIZE (ZEA MAYS L.),INBREDS AND HYBRIDS IN NORTHERN ITALY
No full textON THE INFLUENCE OF BARLEY YELLOW DWARF VIRUS AND MAIZE DWARF MOSAIC VIRUS SINGLY OR DOUBLY INFECTING THE B73 MAIZE INBRED LINE
No full text
Support for resistance: technical analysis and intraday exchange rates
No full text“Support” and “resistance” levels—points at which an exchange rate trend may be interrupted and reversed—are widely used for short-term exchange rate forecasting. Nevertheless, the levels’ ability to predict intraday trend interruptions has never been rigorously evaluated. This article undertakes such an analysis, using support and resistance levels provided to customers by six firms active in the foreign exchange market. The author offers strong evidence that the levels help to predict intraday trend interruptions. However, the levels’ predictive power is found to vary across the exchange rates and firms examined.Foreign exchange rates ; Forecasting
Hereditary Hemorrhagic Telangiectasia: Success of the Osler Calendar for Documentation of Treatment and Course of Disease
No full textHereditary hemorrhagic telangiectasia (HHT; Rendu-Osler-Weber syndrome) affects the capillary and larger vessels, leading to arteriovenous shunts. Epistaxis is the main symptom impairing quality of life. The aim of the Osler Calendar is to offer information about the extent of the systemic disease and the current state of treatment. A care plan with information on the rare disease and self-treatment of epistaxis was created. Organ examinations and ongoing treatments were recorded. A questionnaire documents the treatment success, including patient satisfaction, frequency of hemorrhage and hemoglobin levels. The patients using the Osler Calendar for at least one year (n = 54) were surveyed. Eighty-five percent of patients (n = 46) used the calendar to gain information about HHT. Seventy-two percent (n = 39) used the Osler Calendar for instructions on the self-treatment of nosebleeds. The calendar increased patients' understanding for the need for organ screenings from 48% (n = 26) to 81% (n = 44). Seventy-nine percent (n = 43) of patients confirmed that the Osler Calendar documented their therapeutic process either well or very well. Fifty-two percent (n = 28) saw an improvement in the therapeutic process due to the documentation. The Osler Calendar records the individual intensity of the disease and facilitates the communication between attending physicians. It is a tool for specialists to review treatment strategies. Furthermore, the calendar enhances patients' comprehension of their condition
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Letter from W. C. Gorgas to Sir William Osler, Oxford, England, April 6, 1918
No full textThis is an item from the William Crawford Gorgas papers. This collection includes material created by and written about Gorgas, as well as material created by other Gorgas family members. His diaries and journals illuminate his life and work for the U.S. Army as a surgeon and span the years he worked in Cuba and Panama. The collection includes official reports and other documents Gorgas wrote and collected, as well as articles and other publications written about Gorgas and his work in sanitation and disease prevention, particularly yellow fever. Correspondence, articles, and other items document the numerous awards and tributes Gorgas received during his life and memorials after his death in 1920. In addition to William Crawford Gorgas material, the collection includes other material belonging to Gorgas family members including Marie Gorgas and their daughter, Aileen Gorgas Wrightson. In 1924, his widow Marie Gorgas published William Crawford Gorgas: His Life and Work. This collection includes manuscripts, galley proofs, and published versions of her work
- …
