124,602 research outputs found
Osima Adası'nın çevresindeki akıntı sistemlerinin oluşturduğu farklı su yapılarının özellikleri üzerine araştırma
No full textOsima Adası Japonyaʼnın ana kara parçası olan Honshuʼnun güneyinde yer almaktadır. Kuroshio Akıntısı, ada etkisi ve Osima Adasıʼnın çevresinin batimetrisi, girdap, upwelling, mixing gibi bazı fiziksel oluşumlara neden olmaktadır. Araştırmanın amacına yönelik olarak sörvey data analizleri ve uygun matematiksel parametreler kullanarak, Osima Adası çevresinde gözlenen fiziksel oluşumlar sonucunda oluşan bazı farklı su yapılarının özelliklerini tespit etmek ve balıkçılık açısından önemli olan primer prodüktivitenin yüksek olduğu alanlar hakkında tahminde bulunmak araştırmanın amacını oluşturmaktadır. Araştırmanın sörvey dataları, Tokyo Balıkçılık Üniversitesiʼne ait Seiyo-maru araştırma gemisi ile, 10-12 Mayıs 2002 tarihlerinde, aquashuttle, ADCP, XBT, termosalinograf ve fluorometre ekipmanları kullanılarak alınmıştır. Sörvey sonucunda, Osima Adasıʼnın batısında, B tipine sahip Kuroshio Akıntısıʼnın etkisiyle oluşan türbülans ve mixing alanları tespit edilmiştir. Ayrıca, Osima Adasıʼnın doğusunda, soğuk su girdabı (cyclonic eddy) ve upwelling oluşumu tespit edilmiştir. Hesaplanan matematiksel parametreler sonucunda; B akıntı tipine sahip Kuroshio Akıntısı ve Senbasi Sığlığıʼnın etkisiyle Osima Adası çevresindeki türbülans ve termoklin oluşumları tespit edilmiştir. Buna ek olarak, Osima Adası çevresindeki farklı akıntı özelliklerinin etkisiyle Von Karman Vortex Street oluştuğu tahmin edilmiştir. Osima Adası; kuvvetli akıntı ve farklı akıntı dağılımları gibi oşinografik etkenlerin olduğu bölgede olmasından dolayı, primer prodüktiviteye olan katkısı ve balıkçılık için potansiyel bölge olması sebebiyle önemlidir
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Thermal distributions of discolored water around Osima and craters of Osima Miharayama by the airborne thermal infrared radiometer.
No full textAs a part of the national program on the prediction of volcanic eruptions, the Hydrographic Department is conducting the investions by the remote sensing technique on the submarine volcanoes
and the volcanic islands.
After Miharayama erupted on Nov. 15, 1986, the Hydrographic Department made 14 time-observations of discolored waters around Osima and craters of Osima Miharayama by the airborne thermal
infrared radiometer AGA 780 and the multiband camera MK-1 from Nov. 22, 1986 to Mar. 18, 1987.
The results are
( 1)Temperature of discolored waters around Osima was lower than that of sea water surrounding discolored water of about l～ 2'C, and there was no higher-temperature discolored water.
( 2) If the discolored water was dense, the origin of it coincided with the lower temperature area of the seawater many times and correlation between the area of the discolored water and the isothermline was good.
( 3)There were many lower temperature areas without the discolored water目
( 4)If the discolored water was thin, correlation between the area of the discolored water and the isotherm line was bad.
( 5) It was suitable to make thermal observations before sunrise to detect the distribution of the sea surface temperature in detail.
( 6) In the daytime observations, sea surface temperature was apt to show no thermal distribution pattern.
( 7)Temperature of the A crater (crater opened at the south wall of the old crater) had kept high.
( 8)Temperature of B craters (craters opened at the north rim of the old crater) showed a tendency to decrease, though samplings were few. Temperature of B craters on March 17 was rather high.
(9) Temperature of C craters (craters opened on the flank of Miharayama) showed a strong tendency to decrease．
Temperature of C craters on March 17 was nearly even to the ground temperature.
(JO) Temperature of A crater, B craters and C craters became higher together before the small eruption on Dec. 18.
As the observation condition was differed at every observation time, careful considerations should be required to discuss the relation between the volcanic activities and the temperature of the craters.Publishe
Different pharmacokinetics, antithrombotic activity and bleeding effects of heparin and two new fragments administered in rat by subcutaneous route
No full textNative heparin (CAS 9005-49-6) and its two new fragments, low molecular weight heparin (LMW-H, 5 kDa) and oligo-heparin (oligo-H, 2 kDa) obtained by radical degradation were characterized as to their physicochemical properties. Heparin fragments differ from unfractionated heparin only in molecular weight. The pharmacokinetics and some pharmacological effects, bleeding and antithrombotic activity, of the three different molecular weight heparins were investigated. The plasma concentrations were determined by an amidolytic method which measures inhibiting effect on factor Xa. The blood levels of each substance were derived from their in vitro calibration curves. The examination of the pharmacokinetics parameters allowed to evaluate the differences in the bioavailability, absorption rate and elimination mechanisms between the three different heparins. The bioavailability, the absorption rate and the distribution of the molecules of heparins in biological compartments depend on the molecular weight. LMW-H and oligo-H exhibit greater antithrombotic activity than unfractionated heparin when administered subcutaneously. The pharmacokinetic behaviour of oligo-H considerably differs from that of unfractionated heparin and LMW-H. This new drug is able to bind cells and plasma proteins differently from heparin and LMW-H. The capacity of oligo-H to bind smooth muscle cells and to interact with myosin is discussed in relation to the bleeding effect
Effect of heparin derived fractions on the proliferation and protein synthesis of cells in culture.
No full textWe investigated the effect of sulfated oligosaccharides derived from depolymerization of heparin on the proliferation and protein synthesis of smooth muscle cells (SMC), hamster kidney (BHK-21) and lung (V-79) fibroblasts, rat hepatoma cells (FAO) and human promyelocytes (HL-60). BHK-21 and FAO showed the highest sensitivity to heparin; V-79 and HL-60 cells were completely resistant. LMWH (Low Molecular Weight Heparin) (MW 4.5 kD) was as effective as unfractionated heparin in reducing cell proliferation. The oligo-derivative 381/1 (MW 2 kD) was effective only on FAO and BHK-21 cells; oligo-derivative 381/2 (MW 1KD) had a negligible effect. The anti-proliferative effect was associated with an increased secretion of some protein classes. This effect was not present in heparin-resistant cells. In conclusion when the molecular size of heparin derivative is reduced below 2 kD (i.e. the size of a hexasaccharide) the anti-proliferative activity decreases dramatically
Effect of heparin on cell proliferation: Lack of correlation with heparin binding sites on cell membrane
No full textIn this study an attempt was made to correlate the in-vitro anti-proliferative effect of heparin with the heparin binding on the cell surface. Cells with different sensitivities to the anti-proliferative effect of heparin (BHK-21, FAO, SMC, BAEC, A-431, V-79, and skin fibroblasts) were incubated with [H-3]heparin either in the presence or in the absence of unlabelled heparin. A saturable binding was found only in BHK-21, FAG, SMC, BAEC and V-79. Scatchard analysis revealed the presence of a single class of binding sites. The binding of [H-3]heparin was efficiently displaced by unlabelled heparin, pentosan polysulfate and low-molecular-weight heparin, but not by dermatan sulfate. Although the sensitivity to the anti-proliferative effect of heparin varied considerably among the cell types (BHK-21 >SMC, FAO >BAEC >V-79), there was no correlation between the reduction of proliferation of these cells and either their heparin binding capacity or the number of binding sites per cell
Pragmatic Case Studies as a Source of Unity in Applied Psychology
No full textTo unify or not to unify applied psychology: that is the question. In this article we review pendulum swings in the historical efforts to answer this question—from a comprehensive, positivist, “top-down,” deductive yes between the 1930s and the early 60s, to a postmodern no since then. A rationale and proposal for a limited, “bottom-up,” inductive yes in applied psychology is then presented, employing a case-based paradigm that integrates both positivist and postmodern themes and components. This paradigm is labeled “pragmatic psychology” and, its specific use of case studies, the “Pragmatic Case Study Method” (“PCS Method”). We call for the creation of peer-reviewed journal-databases of pragmatic case studies as a foundational source of unifying applied knowledge in our discipline. As one example, the potential of the PCS Method for unifying different angles of theoretical regard is illustrated in an area of applied psychology, psychotherapy, via the case of Mrs. B. The article then turns to the broader historical and epistemological arguments for the unifying nature of the PCS Method in both applied and basic psychology.Peer reviewe
Dr. Edwin Wright Collection: Author Unknown
No full textNotes - The author relates several short stories about his neighbours including Alex McDonell, homesteading and life around Meanook and Athabasca (1 page
- …
