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    Učinak transkranijalne magnetske stimulacije na kvalitetu spavanja kod osoba s velikim depresivnim poremećajem

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    Poremećaj spavanja je rizični čimbenik za depresiju, ali i jedan od ključnih simptoma velikog depresivnog poremećaja (VDP). Većina danas korištenih antidepresiva izaziva supresiju REM faze spavanja pa tako posredno povećava problem. Transkranijalna magnetska stimulacija (TMS) dokazanog je učinka na smanjivanje težine VDP, međutim u literaturi nedostaje dokaz njenog učinka na poremećaje spavanja. Cilj rada bio je ispitati učinkovitost TMS-a na kvalitetu spavanja kod osoba s VDP. Hipoteza : nakon četiri tjedna liječenja TMS povećava se kvaliteta spavanja kod osoba s VDP. Provedena je randomizirana kontrolirana klinička studija u Psihijatrijskoj bolnici „Sveti Ivan“. Protokol istraživanja odobrilo je Etičko povjerenstvo ustanove i svi bolesnici potpisali su informirani pristanak na sudjelovanje. Glavni ishod bio je ukupni rezultat Epworth ljestvice pospanosti (ESS). Neovisna varijabla bila je liječenje TMS tijekom četiri tjedna dodatno na standardnu terapiju antidepresivima. Ovo istraživanje utvrdilo je statistički značajno smanjenje pospanosti kao indikatora poboljšanja kvalitete spavanja u skupini liječenoj dTMS, ali ne i u skupini liječenoj rTMS, u odnosu na skupinu liječenu samo antidepresivima. Taj je učinak dTMS bio neovisan od dobi, spolu, trajanju VDP, težini VDP pri uključivanju mjerenoj pomoću HAM-D17, dobi kod prve dijagnoze VDP, liječenju SIPPS, IPPSiN, antipsihoticima i benzodiazepinima. Taj je učinak dijelom bio neovisan i o ukupnom učinku na liječenje VD

    INCIDENCE OF CLOSTRIDIOIDES DIFFICILE NOSOCOMIAL INFECTIONS IN PSYCHIATRIC PATIENTS

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    Većina rizičnih čimbenika za bolničku infekciju Clostridioides difficile (CDI) veća je u bolesnika hospitaliziranih u psihijatrijskoj ustanovi nego u bolesnika liječenih u drugim vrstama ustanova, ali je broj istraživanja na toj populaciji razmjerno malen. Cilj ovog istraživanja bio je procijeniti učestalost bolničke CDI u bolesnika liječenih u psihijatrijskoj bolnici. Provedena je retrospektivna studija incidencije od 2017. do 2021. godine u Klinici za psihijatriju Sveti Ivan u Zagrebu na populaciji bolesnika hospitaliziranih duže od 48 sati bez simptoma CDI tijekom prva dva dana po prijemu. Prosječna stopa incidencije (SI) za pet godina iznosila je 0,88 na 10.000 bolesničkih dana hospitalizacije (95%-tni interval pouzdanosti, IP 0,70; 1,12). Omjer stopa incidencije (OSI) bio je tijekom 2019. – 2021. statistički značajno veći nego tijekom 2017. – 2018. i nakon prilagodbe za dob i spol bolesnika (OSI = 1,82; 95% IP 1,06; 3,12; p = 0,027). Incidencija je bila veća u žena nego u muškaraca (OSI = 1,97; 95% IP 1,14; 3,38) nakon prilagodbe za dob bolesnika. Incidencija je bila najveća u dobnoj skupini 75 do 84 godina (stopa incidencije = 6,98 (95% IP 5,01; 9,71) u odnosu na mlađe od 64 godine kada su slučajevi CDI otkrivani vrlo rijetko. Najveći broj bolesnika s CDI bio je liječen na odjelima za demencije, palijativu i muškom odjelu za produženo liječenje. Čini se da opća populacija hospitaliziranih psihijatrijskih bolesnika nema rizik za CDI viši od bolesnika u drugim ustanovama, ali radi se o heterogenoj populaciji u kojoj neke skupine bolesnika na određenim odjelima imaju izrazito povišene rizike i zahtijevaju posebnu skrb.Most risk factors for hospital-acquired Clostridioides difficile infection (CDI) are higher in patients hospitalized in psychiatric institutions than in patients treated in other types of institutions, but the number of studies on this population is relatively small. The aim of this study was to assess the frequency of nosocomial CDI in patients treated in a psychiatric hospital. A retrospective incidence study was conducted from 2017 to 2021 at the Sveti Ivan Psychiatry Clinic in Zagreb on the population of patients hospitalized for more than 48 hours without CDI symptoms during the first two days after admission. The average five-year incidence rate (IR) was 0.88 per 10,000 person-days of hospitalization (95% confidence interval, CI 0.70, 1.12). The incidence rate ratio (IRR) was during 2019 - 2021 statistically significantly higher than during 2017 – 2018. even after adjusting for patient age (IRR = 1.82; 95% CI 1.06; 3.12; p = 0.027). Incidence was higher in women then in men (IRR = 1.97; 95% CI 1.14; 3.38) after adjustment for age. Incidence was highest in the age group 75 to 84 years (IR = 6.98 (95% CI 5.01; 9.71) compared to those younger than 64 when CDI cases were detected very rarely. The largest number of patients with CDI were treated in dementia, palliative care and male long-term care units. The general population of hospitalized psychiatric patients does not appear to have a CDI risk higher than in other institutions, but it is a heterogeneous population in which some groups in some departments have extremely high risks and require special care

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Variations on the Author

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    “Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods

    Author Index

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    koamabayili/VECTRON-author-checklist: VECTRON author checklist

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    We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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