1,721,013 research outputs found
Metagenomik Alalysis of Environmental Microbial Sources: Case Study of Çal Cave
No full textMetagenomic Analysis Of Environmental Microbial Sources: Case StudyOf Çal CaveHasan Demirci1, Emel Ordu1*1 Department of Molecular Biology and Genetics, Yildiz Technical University, Faculty of Arts and Sciences, ,Turkey*Corresponding Author: [email protected], which constitute the vast majority of life forms in the environment, have animportant usage in the biotechnological fields such as medicine, food, energy, agriculture etc.However, it is known that 1% of these microbial diversity have been identified withtraditional cultivation methods, and a very few of them have been cultured and employed inindustrial purpose. Metagenomics, which is a culture-independent approach, and developmentof next-generation sequencing technologies provide not only a wealth of phylogeneticinformation about the environmental microbial samples but also broaden the microbialresource utilization for industrially important enzyme researches. Caves where representunique environments in terms of microbial flora, are ideal habitats for searching novelmicroorganisms, consequently new enzymes. Çal cave in Trabzon is one of the importantkarstic caves in Turkey. We explored the microbial diversity of Çal cave by metagenomicanalysis in order to understand the potential of genomic sources in terms of new enzymes andbioactive compounds meeting industrial demand. Early results showed that cave soil wasdominated by Actinobacteria and Proteobacteria well known as potential sources of bioactivecompounds.Keywords: Actinobacteria, cave soil, metagenomics, Proteobacteria, taxonomic profiling,Acknowledgements: "This work was supported by Research Fund of the Yildiz TechnicalUniversity. Project Number: FDK-2019-3586 ".</p
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Increasing the thermostability of NADdependent formate dehydrogenase from Candida methylica by optimization of surface electrostatic interaction
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Effects of cysteine/cystine engineering on thermal stability of formate dehydrogenase from Candida methylica
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Cloning of Novel Green Solvent Tolerant Hydrolytic Enzymes from Extremophilic Microorganisms
No full textNADdependent formate dehydrogenase from Candida methylica with the increased thermostability
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