10 research outputs found
Impacto de los ácidos grasos poliinsaturados omega 3 en la expresión de FOXP3 y anfiregulina como marcadores de linfocitos T involucrados en la regeneración muscular en distrofia muscular de Duchenne
No full text
Ayesha Dean’s Bravery In Seville: Fearless as a Path to Maturity
No full textThis research analyzes the psychoanalytic characterization that focuses on the decisions made by Ayesha Dean when handling cases in Melati Lum's novel Ayesha Dean and the Seville Secret (2019). This study uses a descriptive qualitative method and applies Sigmund Freud's psychoanalysis theory (1923), which covers the id, ego, and superego. This study finds how Ayesha Dean copes and makes quick decisions while navigating as a detective handling a major case. This research highlights three main points, namely the unconscious desire (id), rational actions (ego), and how morality and conscience work (superego). The author concludes that the actions taken by the main character cannot be separated from the role of the people around her and her strong faith in God. Ayesha's intelligence and courage support how her character is developed through each case she solves. The author hopes that future research will provide a more in-depth analysis and explore more about the character of Muslim girls who have extraordinary abilities in solving these criminal cases
Perlindungan Hukum Terhadap Data Pribadi Pengguna Aplikasi Penyedia Jasa Layanan Publik Pedulilindungi
No full textDi tengah terjadinya pandemi Covid-19 saat ini, seluruh negara termasuk
Indonesia mencari banyak upaya untuk menekan penyebaran virus covid-19, salah
satu upaya yang sudah dilakukan oleh Pemerintah Indonesia adalah dengan
menciptakan aplikasi PeduliLindungi. Dalam aplikasi PeduliLindungi, masyarakat
akan dimintakan data berupa Nama Lengkap, Nomor Induk Kependudukan (NIK),
dan Nomor Telepon. Aplikasi PeduliLindungi dapat digunakan jika masyarakat
sudah memberikan data pribadinya. Aplikasi PeduliLindungi akan memberikan
fasilitas berupa penyediaan sertifikat online serta pengguna aplikasi akan diberikan
informasi terkait lokasi yang hendak dikunjunginya untuk menghindari kerumunan
sehingga penyebaran covid-19 dapat diminimalisir. Namun, dibalik kemudahan
yang diberikan pemerintah melalui aplikasi PeduliLindungi hal tersebut belum
dapat menjamin keamanan data pribadi masyarakat saat menggunakan aplikasi
PeduliLindugi tersebut.
Metode penelitian yang penulis gunakan adalah penelitian yuridis normatif
dengan pendekatan perundang-undangan. Dalam penelitian menggunakan metode
ini, penulis menganalisis mengenai perlindungan hukum bagi data pribadi
masyarakat saat menggunakan aplikasi penyedia jasa layanan publik
PeduliLindungi serta seperti apa pertanggungjawaban hukum penyelenggara jasa
apabila data pribadi masyarakat megalami kebocoran.
Hasil penelitian yang penulis peroleh dalam melakukan penelitian adalah bahwa Perlindungan Hukum terhadapat Pengguna aplikasi PeduliLindungi dalam hal ini mengenai Data Pribadi masyarakat dapat ditinjau berdasarkan Perjanjian (Syarat dan Ketentuan yang terdapat dalam aplikasi) dan berdasarkan ketentuan perundang-undangan yang berlaku di Indonesia. Dalam hal jika penyedia jasa layanan publik PeduliLindugi gagal menjamin keamanan data pribadi masyarakat,
maka pertanggungjawaban penyedia jasa dapat ditinjau dari UU Perlindungan
Konsumen, PP PSTE, Permenkominfo, UU ITE serta UU tentang Pelayanan Publik./
In the midst of the current Covid-19 pandemic, all countries including
Indonesia are looking for many efforts to suppress the spread of the COVID-19
virus, one of the efforts that have been made by the Government of Indonesia is to
create the PeduliLindung application. In the PeduliLindung application, the public
will be asked for data in the form of Full Name, Population Identification Number
(NIK), and Telephone Number. The PeduliLindung application can be used if the
public has provided their personal data. The PeduliLindung application will
provide facilities in the form of providing online certificates and application users
will be given information regarding the locations they want to visit to avoid crowds
so that the spread of COVID-19 can be minimized. However, behind the
convenience provided by the government through the PeduliLindung application,
this has not been able to guarantee the security of the public's personal data when
using the PeduliLindugi application.
The research method that the author uses is a normative juridical research
with a statutory approach. In research using this method, the authors analyze the
legal protection for public personal data when using the PeduliLindungi public
service provider application and what the legal liability of service providers will be
if the public's personal data is leaked.
The results of the research that the authors obtained in conducting the
research are that the Legal Protection of PeduliLindung application users in this
case regarding the public's Personal Data can be reviewed based on the Agreement
(Terms and Conditions contained in the application) and based on the provisions
of the legislation in force in Indonesia. In the event that the PeduliLindugi public
service provider fails to ensure the security of the public's personal data, the responsibility of the service provider can be reviewed from the Consumer
Protection Law, PP PSTE, Permenkominfo, ITE Law and the law on Public
Services
recurrent ARG557CYS mutation as the cause of hereditary mucoepithelial dysplasia in a family with high clinical variability
No full textInvestigación de públicos potenciales en el Museo Nacional de las Culturas
No full textDebido a que el Museo Nacional de las Culturas enfrentó algunas deficiencias en sus estrategias de captación de público, se consideró necesario realizar un estudio que sirviera para obtener un conocimiento sistemático (intereses, motivaciones, expectativas, necesidades) del público potencial, con el propósito básico de incrementar la asistencia, mejorar las prestaciones del museo con los públicos actuales y diseñar programas vinculatorios.</p
Stem cell research in Indonesia from 2003 to 2022: A bibliometrics analysis
No full textContext: Stem cell research has become popular in Indonesia for more than a decade. The scope of research involves in vitro to animal studies as well as human trials. However, no evidence proved its trend.
Aims: To analyze the trends and patterns of stem cell research in Indonesia from 2003 to 2022 using a bibliometric analysis of the Scopus database.
Methods: The data for the paper were retrieved from Scopus and then analyzed using bibliometrics. Statistical data analysis was performed.
Results: The results showed that stem cell research in Indonesia has been increasing steadily over the years, with the majority of publications focusing on “Medicine”, “Biochemistry, Genetics, and Molecular Biology” and “Pharmacology, Toxicology, and Pharmaceutics”. It was found that a total of 260 related articles had been published. Rantam was identified as the most productive author, and the authorship network analysis identified nine clusters of authors. The keywords “stem cells”, “culture”, “proliferation”, “differentiation”, and “tissue engineering” were the most frequently used in the publications analyzed.
Conclusions: Overall, this study provides valuable insights into the development of stem cell research in Indonesia and may inform future research and funding decisions in this field
Patterns of reduced cortical thickness and striatum pathological morphology in cocaine addiction
No full textAbstractSubstance addiction is regarded as an important public health problem, perpetuated by fronto-striatal circuit pathology. A usual finding in neuroimaging human and murine studies is cortical thinning and lower volume when compared to healthy controls. In this study we wished to replicate cortical thinning findings and find if striatum morphology may explain the cortical pathology. For this we analyzed T1w neuroimaging data from an ongoing addiction Mexican dataset. This dataset includes cocaine addicts diagnosed by expert psychiatrists and healthy controls. For the analysis we used voxel-based morphometry, cortical thickness and volumetric analysis of the basal ganglia, and we correlated striatum volume with cortical thickness to find pathological patterns. Our group contrast showed cortical thinning and striatum volume differences in cocaine addicts correlated to their years of substance use, craving and age. Our correlation between striatum-cortex morphology showed higher significant correlations in healthy controls, not observed in cocaine addicts. The correlation between striatum volume and cortical thickness in healthy controls involved similar areas as those shown with less cortical thickness in cocaine addicts. We suggest that striatum morphological changes in addiction may explain the pattern of cortical thinning observed across several substances addiction studies.Research Data Related to this SubmissionData sethttps://zenodo.org/record/1409808#.W5E3oCOZPIF Patterns of reduced cortical thickness and striatum pathological morphology in cocaine addictionThis dataset includes all the data and scripts needed to reproduce the analysis and results on the manuscript “Patterns of reduced cortical thickness and striatum pathological morphology in cocaine addiction” (link). The brain data is not raw, as T1w were not defaced. We will do so in the near future for version 2.0. Instead we include only the “output/thickness” files used in the final analysis. For the use of raw T1w images, please contact the main author EAGV.</jats:sec
An ITPR1 Variant in the IP3-ITPR1 Binding Pocket Associated With a Clinical Phenotype of Athetoid Cerebral Palsy.
No full textA de novo, missense variant in ITPR1-inositol 1,4,5-trisphosphate receptor type 1 (ITPR1), p.(Tyr567Cys), was identified by trio whole-genome sequencing in an individual diagnosed with Spinocerebellar ataxia 29 (SCA29) who was affected by cerebral palsy and global developmental delay. The variant affects a residue involved in Inositol 1,4,5-trisphosphate (IP3)-ITPR1 binding. Genotype-Phenotype correlation analysis of the set of missense variants affecting nine residues involved in IP3-ITPR1 binding in the current case and 170 reports of individuals with ITPR1 variants showed a significantly higher frequency of phenotypic features related to neurodevelopmental delay in these variants than in other ITPR1 variants. Our proband was diagnosed with cerebral palsy, as were five other published individuals diagnosed with SCA29. Two of these individuals were siblings who were found to have the variant p.(Arg269Trp), also located in the IP3-ITPR1 binding pocket. These observations suggest that genotype-phenotype correlations exist in the ITPR1 gene and underscore the importance of data sharing and reuse to elucidate the natural history of rare neurodevelopmental diseases
Framing de Paz: Análisis de la construcción mediática entre medios tradicionales y medios institucionales en el posconflicto en Bogotá.
No full textEste trabajo de grado es una exploración exhaustiva de la
interpretación del proceso de
paz y reconciliación en Colombia, enfocándose en la cobertura de medios de comunicación
prominentes y las estrategias comunicativas de entidades gubernamentales durante el año
2021. Utilizando un enfoque mixto que combina análisis cuantitat ivo y cualitativo, el estudio
desentraña cómo los términos relacionados con la paz son empleados en la narrativa de los
periódicos El Tiempo y El Espectador, la revista Semana, y la Al ta Consejería para la Paz,
Víctimas y Reconciliación (ACPVR) de la Alcaldía de Bogotá. Mediante el uso de nubes de
palabras y el análisis de framing, la investigación revela diferencias significativas en la
frecuencia y el contexto de las palabras clave, a sí como en los encuadres de paz adoptados
por estos actores informativos.
El estudio evidencia una diversidad en la representación mediática, mostrando cómo
cada medio y entidad gubernamental construye su propio discurso sobre la paz y la
reconciliación, moldeando así la percepción pública del proceso postconflicto en Colombia.
Este trabajo contribuye al entendimiento del papel de los medios en la construcción social de la
realidad y ofrece una mirada crítica sobre cómo las narrativas mediáticas pueden influir en la
memoria histórica de una nación que busca cerrar las heridas de su pasado violento.This degree work is a comprehensive exploration of the interpretation of the peace and reconciliation process in Colombia, focusing on the coverage of mainstream media and the communication strategies of governmental entities during the year 2021. Using a mixed approach that combines quantitative and qualitative analysis, the study shows how peace-related terms are employed in the narrative of the newspapers El Tiempo and El Espectador, the magazine Semana, and the Office of the Counselor for Peace, Victims and Reconciliation (ACPVR) of the Office of the Mayor of Bogota. Through the use of word clouds and framing analysis, the research reveals significant differences in the frequency and context of key words, as well as in the peace frames adopted by these news actors. The study evidences a diversity in media representation, showing how each media outlet and government entity constructs its own discourse on peace and reconciliation, thus shaping the public perception of the post-conflict process in Colombia. This work contributes to the understanding of the role of the media in the social construction of reality and offers a critical look at how media narratives can influence the historical memory of a nation seeking to heal the wounds of its violent past
