1,720,962 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
We have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Actomyosin Spatiotemporally Regulates Par Polarity Dynamics To Create Neural Stem Cell Asymmetry
PDF of dissertation and zipped file of 13 videos.Pattern formation, or specifically symmetry breaking, is a fundamental process essential for proper asymmetric cell division. In asymmetrically dividing stem cells, the evolutionarily conserved Par polarity complex localizes to a discrete Par domain to facilitate unequal distribution of fate determinants into the daughter cells–thereby ensuring a binary cell division outcome where daughters will acquire distinct fates. Hence proper asymmetric cell division requires the spatiotemporal distribution of Par proteins to be precisely coordinated. While a number of studies have been conducted to understand how Par activity creates downstream asymmetry, how the Par complex acquires asymmetry remains unclear. Two standing models exist to explain for how Par proteins can become polarized. In the one-cell stage C. elegans embryo, gradients of contractile force created by the cortical actomyosin cytoskeletal network generates cortical flow towards the anterior pole. Concurrently, symmetrical Par proteins that are entrained within the network becomes advected via bulk motion of the cortex, consequently becoming anteriorly segregated. In Drosophila neuroblasts, Par complex exchanges between the unpolarized, cytoplasmic and polarized, apical states; it is thus thought to become polarized to the apical domain via a direct, asymmetric targeting mechanism.
In this dissertation, we examined the spatiotemporal distribution profile of cortical Par proteins and actomyosin in mitotic neuroblasts using a full volume, rapid live imaging approach to capture change in cortical protein distribution as they transition from an unpolarized to a polarized state. In the second chapter, we characterized the Par protein dynamics and investigated if the actomyosin network is essential for Par dynamics. This study demonstrated that Par polarization is a dynamic, multistep process, consisting of asymmetric targeting of cytoplasmic Par into discrete, apical foci and F-actin dependent coalescence of Par foci at the apical pole. In the third chapter, we determined the cortical dynamics of actomyosin and identified that coalescence is spatiotemporally linked to myosin II driven flow. Our studies suggest a conserved role for actomyosin in Par polarity in C. elegans embryos and Drosophila neuroblasts.
This dissertation contains previously published and unpublished co-authored material. Live imaging movies of Par proteins and actomyosin are attached in the supplemental files associated with this dissertation.2022-08-2
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ABL Tyrosine Kinase Stimulates PUMA Protein Expression
ABL is an ubiquitously expressed non-receptor tyrosine kinase involved in multiple cellular functions including programmed cell death. Upon DNA damage, ABL has been shown to upregulate PUMA, p53 upregulated modulator of apoptosis, and causes downstream mitochondrial intrinsic apoptotic events. However, the mechanism by which ABL regulates PUMA expression remains unknown. We have shown that ABL does not change PUMA protein subcellular localization through immunofluorescence. Through protein and RNA quantification, we showed that overproduction of PUMA RNA leads to an increase in PUMA protein expression. ABL requires a functional kinase domain to stimulate PUMA protein expression. Inhibition of ABL kinase activity using Imatinib diminishes the ability of ABL to induce PUMA protein expression
Author-wise bibliometric analysis based on entropy.
Author-wise bibliometric analysis based on entropy.</p
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