1,720,961 research outputs found
Clinical Studies on Serum Glycoproteins in Patients with Maingnant Neoplasm Part Ⅱ. Changes in α(1)-acid glycoprotein and α(1)-antitrypsin levels during therapeutic procedures and a prognostic value of these glycoproteins in patients with malignant neoplasm
Get PDFSerial determinations of serum α(1)-acid glycoprotein (α(1)-AG) and α(1)-antitrypsin (α(1)-AT) were performed in 43 cases with lung cancer and 25 cases with stomach cancer during therapeutic procedures, and in 31 courses of remission induction-chemotherapies of 23 cases with malignant lymphoma. These studies reveal that changes in serum α(1)-AG levels during chemotherapy would be an index to the efficacy of chemotherapeutic agents for malignant neoplasms because it has been shown that α(1)-AG levels changed in intimate relation to neoplastic processes in almost all the cases of lung or stomach cancer. Especially, in malignant lymphoma, changes in α(1)-AG levels during the clinical course showed such a close relation to vicissitudes of lymphadenopathy that serial determinations of this glycoprotein was regarded as a reliable index not only for the efficacy of chemotherapy but also for the early detection of relapse prior to the manifestations of clinical symptoms. On the other hand, changes in α(1)-AT levels did not correlate to the progression of canecrous lesions in almost half the cases recieving various chemotherapeutic agents and corticosteroids. It was considered that these agents, especially corticosteroids, might be directly concerned with metabolism of this glycoprotein. In patients with lung or stomach cancer who did not obtain any clinical improvement during chemotherapy, significant correlation was observed between α(1)-AG as well as α(1)-AT levels prior to chemotherapy and their life spans. Therefore, it was possible to set up a regression line of life spans against these glycoprotein levels and life spans of ineffective cases to chemotherapy could be estimated roughly according to this regression line
Clinical Studies on Serum Glycoproteins in Patients with Malignant Neoplasm Part Ⅰ. Relationship between degree of progression of the diseases and serum α(1)-acid glycoprotein and α(1)-antitrypsin
Get PDFSerum α(1)-acid glycoprotein (α(1)-AG) and α(1)-antitrypsin (α(1)-AT) levels were measured in 30 controls, 57 patients with nonmalignant disease and 249 patients with malignant neoplasm of various sites and stages. An almost parallel increase of these glycoproteins was observed in patients with advanced cancer except hepatoma, but in cases with localized lesion these serum levels remained normal. In 85 patients with lung cancer and 49 with stomach cancer, considerable relationship was observed between the serum levels of these glycoproteins and degree of progression of cancerous lesions. Therefore, it seems that these glycoprotein levels are a relible index for staging malignant diseases. In Hodgkin's disease, however, there was no relationship between these serum levels and its clinical stage, but these glycoprotein levels in B cases of Hodgkin's disease were significantly elevated than in A cases. Evaluation of these glycoproteins would serve as a diagnostic means in patients with hepatomegaly and/or jaundice, since in patients with hepatoma α(1)-AG levels are decreased and α(1)-AT levels are elevated, in patients with metastatic liver cancer both of them are significantly elevated and in cirrhosis of the liver α(1)-AG levels are clearly decreased and α(1)-AT levels remain normal
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
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