1,720,974 research outputs found
Supplemental Material, DS1_VET_10.1177_0300985818777035 - Canine Splenic Nodular Lymphoid Lesions: Immunophenotyping, Proliferative Activity, and Clonality Assessment
No full textSupplemental Material, DS1_VET_10.1177_0300985818777035 for Canine Splenic Nodular Lymphoid Lesions: Immunophenotyping, Proliferative Activity, and Clonality Assessment by Silvia Sabattini, Rosa Maria Lopparelli, Antonella Rigillo, Mery Giantin, Andrea Renzi, Chiara Matteo, Ombretta Capitani, Mauro Dacasto, Marisa Mengoli, and Giuliano Bettini in Veterinary Pathology</p
A Rare Case of Salmonella Spp. Osteomyelitis in a Dog
Full text linkOsteomyelitis is an inflammatory condition of bone usually caused by infectious agents such
as bacteria, fungi or viruses. The disease is characterized by systemic illness, pain and soft tissue
swelling with visible radiographic alterations in bone. The most common bacteria isolated in cases
of osteomyelitis in dogs and cats are Staphylococcus spp. (60% of cases), followed by Escherichia
coli and Streptococcus spp. [1,2]. To our knowledge, this is the first canine case of Salmonella spp. osteomyelitis
Comparison between May Grünwald-Giemsa and rapid stains in fine-needle aspirates of canine mast cell tumor: diagnostic and prognostic implications
No full textIntroduction
Mast cell tumors (MCTs) are often diagnosed by cytology based on the identification of their characteristic purple intracytoplasmic granules with methanolic Romanowsky stains, including May Grünwald-Giemsa (MGG). In clinical practice, aqueous Romanowsky stains are commonly used because of their rapidity, but the risk exists that mast cell granules may not stain properly. The purpose of this study was to investigate the phenomenon of hypogranularity of MCT with rapid staining (RS) in terms of frequency and correlations with tumor characteristics, along with diagnostic and prognostic implications.
Materials and Methods
A prospective study was carried out on cytologic preparations of histologically-confirmed canine primary MCTs and metastatic lymph nodes. For each case, good-quality smears were stained with both MGG and RS and comparatively assessed.
Results
Fifteen out of 60 (25%) primary canine MCTs were hypogranular with RS (P=0.002). These were predominantly cutaneous high-grade tumors and in 7 of them (11.7%) a certain diagnosis could not be made with RS. Accuracy in grading assessment was not significantly different compared with MGG (79% vs 83%). Ten of 25 (40%) metastatic lymph nodes were hypogranular with RS (P=0.002); the negative predictive value in the detection of nodal metastases, assessed with three independent observers, was significantly lower (100% vs 73%; P=0.010).
Discussion
This study confirms that RS can be ineffective in staining MCT granules, especially in biologically aggressive tumors, and can occasionally prevent the achievement of a correct diagnosis. The use of RS is discouraged for the search of nodal metastases, as the identification of isolated mast cells can be particularly challenging
Case report: Sublingual mucinosis in a dog
Full text linkA 11-month-old male intact Shar-Pei (26. 5 kg) was presented for a bilateral sublingual swelling of 4 months duration. The exploration of the oral cavity highlighted the presence of bilateral sublingual swellings, primarily consistent with bilateral ranula. The bilateral disease was treated with two subsequent surgeries 4 weeks apart. During the surgery, after removing an elliptical portion of the mucosa of the sublingual swelling, the presence of gelatinous tissue was visualized, and no saliva was present. The result of histological exam was oral mucinosis. At the subsequent follow-up the dog was in excellent conditions, without any symptoms. 1 month after the last operation, the dog underwent a visit in sedation to better evaluate the oral cavity. Both surgical sites were well-healed and without the presence of relapses. Upon 8 months follow-up the patient remained free of disease. This is the first reported case of oral mucinosis in sublingual mucosa in dogs. In this case the surgical treatment was curative
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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