170,556 research outputs found
Data for: Trust perceptions among residents surrounding nuclear power plants: a descriptive and explanatory study.
No full textSurvey on responses to radiological emergencies. H2020 Confidence Project. Spanish sampl
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Mitomycin C in highly myopic eyes - Author reply
No full textOphthalmology. 2005 Feb;112(2):208-18; discussion 219.
Mitomycin C modulation of corneal wound healing after photorefractive keratectomy in highly myopic eyes.
Gambato C, Ghirlando A, Moretto E, Busato F, Midena E.
SourceRefractive Surgery Service and Antimetabolite Therapy Research Unit, Department of Ophthalmology, University of Padova, Padova, Italy.
Abstract
PURPOSE: To evaluate the role of topical mitomycin C in corneal wound healing (CWH) after photorefractive keratectomy (PRK) in highly myopic eyes.
DESIGN: Prospective, double-masked, randomized clinical trial.
PARTICIPANTS: Seventy-two eyes of 36 patients affected by high (>7 diopters) myopia.
METHODS: In each patient, one eye was randomly assigned to PRK with intraoperative topical 0.02% mitomycin C application, and the fellow eye was treated with a placebo. Postoperatively, mitomycin C-treated eyes received artificial tears (3 times daily, tapered in 3 months), whereas the fellow eye was treated with fluorometholone sodium 2% and artificial tears (3 times daily, tapered in 3 months).
MAIN OUTCOME MEASURES: Uncorrected visual acuity (UCVA) and best-corrected visual acuity (BCVA), contrast sensitivity, manifest refraction, and biomicroscopy. Contrast sensitivity was determined using the Pelli-Robson chart. Corneal confocal microscopy documented CWH.
RESULTS: Mean follow-up was 18 months (range, 12-36). No side effects or toxic effects were documented. At 12-month follow-up examination, UCVAs (logarithm of the minimum angle of resolution) were 0.4+/-0.48 and 0.5+/-0.53 (P = .03) in mitomycin C-treated eyes and corticosteroid-treated eyes, respectively. At 1 year, corneal haze developed in 20% of corticosteroid-treated eyes, versus 0% of mitomycin C-treated eyes. At 12, 24, and 36 months, corneal confocal microscopy showed activated keratocytes and extracellular matrix significantly more evident in untreated eyes (Ps = 0.004, 0.024, and 0.046, respectively).
CONCLUSION: Topical intraoperative application of 0.02% mitomycin C can reduce haze formation in highly myopic eyes undergoing PRK.
Comment in
Ophthalmology. 2006 Feb;113(2):357; author reply 357-8
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
A Multi-Language Comparison of Influences on Author Verification using Character N-Grams
No full textWe create a new multi-language corpus for author verification based on Wikipedia talkpages, and evaluate the influence that differences in topic and time have on character n-gram author profiles. Topic alignment between two texts is found to increase author verification precision, and an authors writing style is found to change over time, but not more significantly after 3 years than after 1 year.Information ArchitectureWISElectrical Engineering, Mathematics and Computer Scienc
A 0.12mm<sup>2</sup> Wien-Bridge Temperature Sensor with 0.1°C (3σ) Inaccuracy from -40°C to 180°C
No full text Resistor-based temperature sensors can achieve much higher resolution and energy efficiency than conventional BJT-based sensors [1], but they typically occupy more area (> 0.25 mm 2 ) and have lower operating temperatures (le 125 {circ} {C}) [2]-[4]. This work describes a 0.12mm 2 resistor-based sensor that uses a Wien-bridge (WB) filter to achieve 0.1 {circ} {C} (3 sigma) inaccuracy from - 40 {circ} {C} to 180 {circ} {C}. Compared to a state-of-the-art WB sensor [4], it occupies 6 × less area and achieves comparable relative accuracy over a 76% wider operating range. Session 10.3 Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic InstrumentationMicroelectronic
A ±25A Versatile Shunt-Based Current Sensor with 10kHz Bandwidth and ±0.25% Gain Error from -40°C to 85°C Using 2-Current Calibration
No full textAccurate current sensing is critical in many industrial applications, such as battery management and motor control. Precise shunt-based current sensors have been reported with gain errors of less than 1% over the industrial temperature range (-40°C to 85°C) [1]–[4]. However, since they are intended for coulomb counting, their bandwidth is limited to a few tens of Hz, making them unsuitable for battery impedance or motor-current sensing. This paper presents a current sensor with a wide (10kHz) bandwidth and a tunable temperature compensation scheme (TCS), which allows it to be flexibly used with different types of shunts while maintaining high accuracy. A low-cost room-temperature calibration scheme is proposed to optimize gain flatness over temperature by exploiting the shunt's self-heating at large currents. Over the industrial temperature range and a ±25A current range, it achieves state-of-the-art gain error (±0.25%) with both low-cost PCB and stable metal-alloy shunts.Green Open Access added to TU Delft Institutional Repository 'You share, we take care!' - Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Electronic InstrumentationMicroelectronic
Diversity of Innovative Strategy as a Source of Technological Performance
No full textThis paper explores the impact of diversity of innovative strategies of firms upon the industrial dynamics through a micro-simulation model. We consider two types of firms each one being characterised by a specific innovative strategy. Basically we assume that some cumulative firms adopt an internal learning by searching strategy, while noncumulative firms adopt an external learning strategy aiming at absorbing external sources of knowledge. The results show that the co-existence of the two types of firms leads to an oligopolistic structure characterised by asymmetries in the size of firms and high technological performances. Thus the diversity of innovative strategies generates a diversity in firms market shares and is a source of dynamic efficiency in the long run.Industrial dynamics, innovation, diversity, learning
An Article About Albertus C. Van Raalte, Author Unknown, Except for Parts Taken from an Article by Anna C. Post
No full textAn article about Albertus C. Van Raalte, author unknown, except for parts taken from an article by Anna C. Post. The author knew first generation persons in the Holland settlement and therefore, the article has some value.https://digitalcommons.hope.edu/vrp_1890s/1012/thumbnail.jp
Síntesis estereoselectivas de lactonas de origen natural y estudio de actividad biológica
No full textLa Tesis Doctoral explica como se ha llevado a cabo la síntesis total estereocontrolada de la lactona de origen natural aspergillida B, siendo los segundos autores en publicar la síntesis de este macrólido aislado del hongo marino Aspergillus ostianus cultivado en un medio modificado de agua bromada. Este trabajo ha dado lugar a la siguiente publicación preliminar:
a) Stereoselective Synthesis of the Cytotoxic Macrolide Aspergillide B. Santiago Díaz-Oltra, César A. Angulo-Pachón, María N. Kneeteman, Juan Murga, Miguel Carda, J. Alberto Marco, Tetrahedron Lett. 2009, 50, 3783.
También se ha llevado a cabo la síntesis total estereocontrolada de la lactona de origen natural aspergillida A, igualmente aislada del hongo Aspergillus ostianus. En este caso nosotros fuimos los primeros autores en publicar la síntesis de este metabolito natural, dando lugar a la siguiente publicación preliminar:
b) Stereoselective Synthesis of the Cytotoxic 14-Membered Macrolide Aspergillide A. Santiago Díaz-Oltra, César A. Angulo-Pachón, Juan Murga, Miguel Carda, J. Alberto Marco, J. Org. Chem. 2010, 75, 1775.
Aprovechando que con las síntesis de las aspergillidas A y B, se desarrolló una metodología sintética de caracter divergente y debido a que éstas lactonas de origen natural mostraron una actividad citotóxica contra células de leucemia linfocítica en ratones, se aprovechó estudiando las actividades citotóxicas frente a seis líneas de células tumorales de las aspergillidas A y B, junto con las de otros nueve compuestos sintetizados en el contexto de la Tesis. Como consecuencia de este estudio se ha demostrado que el producto no natural (Z)-aspergillida A es el citotóxico más potente de todos los ensayados, siendo particularmente activo en la línea celular HL-60.
Además se llevaron a cabo pruebas de multirresistencia a drogas (MDR) de la aspergillida A y otros ocho compuestos sintetizados en el contexto de esta Tesis. Estos ensayos han demostrado que el efecto MDR no opera sobre los compuestos ensayados en la línea de células P388/MDR. Todos estos resultados se han recopilado en la siguiente publicación:
c) Synthesis and Biological Properties of the Cytotoxic 14-Membered Macrolides Aspergillide A and B. Santiago Díaz-Oltra, César A. Angulo-Pachón, Juan Murga, Eva Falomir, Miguel Carda, J. Alberto Marco., Chem. Eur. J. 2011, 17, 675.
Finalmente se ha conseguido la síntesis total enantioselectiva del estagonólido G, al cual se asignó inicialmente la estructura de una macrolactona de 10 miembros. Nuestra síntesis ha demostrado que:
a) la estructura originalmente propuesta para este compuesto era incorrecta.
b) la estructura correcta del estagonólido G es realmente la de una gamma-lactona.
gracias a este trabajo se han podido corregir los resultados de aislamiento y una síntesis previa del estagonólido G que habían sido publicados con el error anteriormente ya mencionado.
Este trabajo ha dado lugar a la siguiente publicación:
d) Stereoselective Synthesis and Structural Correction of the Naturally Occurring Lactone Stagonolide G. César A. Angulo-Pachón, Santiago Díaz-Oltra, Juan Murga, Miguel Carda, J. Alberto Marco., Org. Lett. 2010, 12, 5752
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