154 research outputs found

    sj-docx-1-bdx-10.1177_26348535221130289 - Supplemental material for Relationships Between Transcranial Doppler Velocity, Von Willebrand Factor, Factor VIII, and Hematological Parameters in Children with Sickle Cell Anemia: A Comparative Cross-Sectional Study

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    Supplemental material, sj-docx-1-bdx-10.1177_26348535221130289 for Relationships Between Transcranial Doppler Velocity, Von Willebrand Factor, Factor VIII, and Hematological Parameters in Children with Sickle Cell Anemia: A Comparative Cross-Sectional Study by Eniola Kehinde Enifeni, Ann Abiola Ogbenna, Alaba Olanrewaju Daramola, Ademola Samson Adewoyin, Oladele Simeon Olatunya and Edamisan Temiye in Plasmatology</p

    The total synthesis of mycothiol and new inhibitors of carbohydrate processing enzymes

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    The work described in this dissertation covers a wide range of disciplines within organic chemistry, with the common goal of obtaining more information about various carbohydrate-processing enzymes. Carbohydrate-processing enzymes are garnering an increasing amount of attention relative to their more well-studied protein-processing counterparts, as they are ubiquitous and implicated in various regulatory, signaling and metabolic processes in eukaryotic cells. Chapter 1 involves the synthesis of anomeric phosphothioates as possible O-GlcNAc transferase inhibitors, and a mechanistic study on the anomeric Pudovik rearrangement of thiophosphites to thiophosphonates is described. Chapter 2 is an account of the development of a facile method for functionalizing 2-methyl thiazoline rings, and several selective GlcNAc-thiazoline-based O-GlcNAcase inhibitors were synthesized by this method. Chapter 3 details the 16-step total synthesis of the M. tuberculosis antioxidant carbohydrate mycothiol by a new intramolecular glycosylation method. The method is amenable to glycosylations of 2-deoxy-2-aminoglyosides, a unique aspect among such reactions. The efficiency of the synthetic route to mycothiol makes it attractive as a template from which to design analogs as potential inhibitors of enzymes involved in the biosynthesis of mycothiol. An apparently unprecedented 1,9-hydride shift is also described in the third chapter. Chapter 4 describes a tripartate prolonged-release drug delivery system, in which the drug of interest (ethynyl estradiol in this study) is coupled, through a variable linker, to another carrier drug with a long half-life and a relatively high inhibitory concentration. The effect of steric bulk on the in vitro release of ethynyl estradiol was evaluated, showing a direct relationship between steric bulk around the ester linkage and ethynyl estradiol release time. In vivo data from pigs also seemed to point to an increase in drug bioavailability with the 3-part system. Finally, chapter 5 describes early efforts to synthesize boronic acid analogs of folic acid and antifolates.Ph.D.Includes abstractVitaIncludes bibliographical referencesby Kehinde Ajay

    Book review: The new age of empire: how colonialism and racism still rule the world by Kehinde Andrews

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    In The New Age of Empire: How Colonialism and Racism Still Rule the World, Kehinde Andrews explores how the intellectual, political and economic frameworks inherited from colonialism are still governing today’s world, resulting in a new age of empire that perpetuates racism, white supremacy and global economic inequalities. This compact and comprehensive book challenges the grand narratives of the Enlightenment, Western linear progress and developmentalism and offers a broader and more complete picture of the continuing problems of racism and the imperial mentality, writes Ayşe Işın Kirenci. If you are interested in this book review, you can listen to a podcast of author Kehinde Andrews discussing The New Age of Empire at an LSE event held on 27 April 2021. The New Age of Empire: How Colonialism and Racism Still Rule the World. Kehinde Andrews. Penguin Books. 2021

    Book review: The new age of empire: how colonialism and racism still rule the world by Kehinde Andrews

    No full text
    In The New Age of Empire: How Colonialism and Racism Still Rule the World, Kehinde Andrews explores how the intellectual, political and economic frameworks inherited from colonialism are still governing today’s world, resulting in a new age of empire that perpetuates racism, white supremacy and global economic inequalities. This compact and comprehensive book challenges the grand narratives of the Enlightenment, Western linear progress and developmentalism and offers a broader and more complete picture of the continuing problems of racism and the imperial mentality, writes Ayşe Işın Kirenci. If you are interested in this book review, you can listen to a podcast of author Kehinde Andrews discussing The New Age of Empire at an LSE event held on 27 April 2021. The New Age of Empire: How Colonialism and Racism Still Rule the World. Kehinde Andrews. Penguin Books. 2021

    Book review: The new age of empire: how colonialism and racism still rule the world by Kehinde Andrews

    No full text
    In The New Age of Empire: How Colonialism and Racism Still Rule the World, Kehinde Andrews explores how the intellectual, political and economic frameworks inherited from colonialism are still governing today’s world, resulting in a new age of empire that perpetuates racism, white supremacy and global economic inequalities. This compact and comprehensive book challenges the grand narratives of the Enlightenment, Western linear progress and developmentalism and offers a broader and more complete picture of the continuing problems of racism and the imperial mentality, writes Ayşe Işın Kirenci. If you are interested in this book review, you can listen to a podcast of author Kehinde Andrews discussing The New Age of Empire at an LSE event held on 27 April 2021. The New Age of Empire: How Colonialism and Racism Still Rule the World. Kehinde Andrews. Penguin Books. 2021

    Ergonomic assessment of work-related musculoskeletal disorders among limited service restaurants

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    Musculoskeletal disorder is one of the most common work-related recordable disorders across all industries. This thesis examines work related musculoskeletal disorders present in limited service restaurants using Texas A&M University Kingsville as a case study. This research provides highlights into the most common musculoskeletal disorder amongst servers, how they can be identified and determining its impact on employees. The outcome indicates a significant relationship between the work demand/work posture and the occupational disorder experienced amongst limited service restaurant employees. Employing various tables, charts, and ordinary least square regression model, with the aid of IBM Statistical Package for Social Sciences (SPSS), this research shows that there is a common musculoskeletal disorder associated with all the five limited service restaurants examined in this case study and shows its effect on employee productivity

    A tradução da literatura pós-colonial de Kehinde de Buchi Emecheta para o português brasileiro

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    Dissertação (mestrado) — Universidade de Brasília, Instituto de Letras, Departamento de Línguas Estrangeiras e Tradução, Programa de Pós-Graduação em Estudos da Tradução, 2023.A imposição da língua inglesa como norma de prestígio durante a colonização britânica desencadeou significativas variações e mudanças no inglês falado nas regiões colonizadas, originando novos usos da língua. A versão normativa foi, então, substituída por um discurso adaptado ao espaço onde as colônias foram estabelecidas, como forma de reconhecimento e valorização de suas próprias culturas e identidades. Do desejo de libertação de valores e conceitos metropolitanos surge a literatura pós-colonial, com o intuito de questionar e negar conceitos impostos pelo poder central, tais como a existência de um código linguístico padrão que deva ser privilegiado. Dentre os escritores pós coloniais está a escritora nigeriana Buchi Emecheta (1944-2017). Em seu livro Kehinde (1994), a trama desenrola-se através de uma língua desconstruída, permeada pelos ideais pós-coloniais. Este trabalho tem por objetivo apresentar uma tradução comentada da obra, inédita para o português brasileiro, investigar e responder que estratégias características da literatura pós-colonial são de fato utilizadas pela autora e como poderiam ser traduzidos os aspectos linguísticos e culturais presentes no livro em questão. Para tanto, serão apresentados exemplos com trechos da tradução em comparação a trechos do texto fonte, com o intuito de oferecer alternativas tradutórias para Kehinde, no contexto brasileiro. Então serão apresentadas as teorias de tradução que orientam a pesquisa, posto que a análise a ser elaborada evolui num âmbito não-prescritivo, será apresentada a Teoria dos Polissistemas, elaborada por Itamar Even-Zohar (1990), e os Estudos Descritivos, desenvolvidos por Gideon Toury (1995). O contexto cultural, histórico e literário e a prática tradutória serão discutidos a partir de teóricos como Bill Ashcroft, Jane Tutikian, Homi Bhabha, Gayatri Spivak, Susan Bassnet, Tejaswini Niranjana, Anthony Pym, entre outros. Desta forma, visto que ainda são poucas as traduções de literatura pós-colonial, principalmente para o português brasileiro, pretende-se contribuir com informações para futuras traduções de textos pós-coloniais.The imposition of the English language as norm of prestige during the British settling resulted in significant variations and changes in the English spoken in the colonized regions, originating new uses of the language. Therefore, the normative version was replaced by a discourse adapted to the places where the colonies had been established, as a recognition and appreciation of their own cultures and identities. The post-colonial literature emerged to question and deny concepts imposed by the imperial power, such as a standard linguistic code that should be privileged. One example of post-colonial literature is Kehinde (1994), written by the Nigerian writer Buchi Emecheta (1944-2017). This work intends to present a commented translation of Kehinde, unpublished for Brazilian Portuguese, investigate and answer which strategies of post-colonial literature are used by the author and how the linguistic and cultural aspects in the text could be translated. Therefore, examples will be presented with excerpts from the translation compared to excerpts from the source text, with the aim of offering translation alternatives for Kehinde, in the Brazilian context. Furthermore, the translation theories that guide the research will be presented, since the analysis to be elaborated evolves in a non prescriptive scope, the Polysystem Theory, developed by Itamar Even-Zohar (1990), and the Descriptive Studies, developed by Gideon Toury (1995). The cultural, historical and literary context and translation practice will be discussed from theorists such as Bill Ashcroft, Jane Tutikian, Homi Bhabha, Gayatri Spivak, Susan Bassnet, Tejaswini Niranjana, Anthony Pym, among others. Still, since post-colonial literature is not so translated, especially to Brazilian Portuguese, this work can contribute for future translations of postcolonial texts.Instituto de Letras (IL)Departamento de Línguas Estrangeiras e Tradução (IL LET)Programa de Pós-Graduação em Estudos da Traduçã

    Patriarchy, Gender Discrimination and Resistance in Buchi Emecheta’s Second Class Citizen (1974) and Kehinde (1994)

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    30cm ; 50p.As one of the most figures of the Nigerian Literature, Buchi Emecheta displays a vivid portrayal of the bitter realities of certain patriarchal practices in the African culture, which not only thwarted Black women but also hampered them from having a position in the society. This study selected two of her novels, Second Class Citizen (1974) and Kehinde (1994). It discusses issues of patriarchy, gender discrimination and Resistance in both novels. This thesis is based on Alice Walker’s Womanism, developed in her collection of essays In Search Of Our Mothers Garden: Womanist Prose (1983). In this analysis we have tried to show that despite the fact that the two works are twenty years apart, the author is still discusses the same issues that come from her cultural and personal experiences. The author has portrayed the oppression practiced towards women. She has depicted how women are dominated by men in patriarchal societies. Emecheta has also described how these women rebel and seek for independence through the process of education. This study concludes that Emecheta succeeds in using resistant and powerful female character, aiming at identifying the suffering of women as she underlines a strong autobiographical quality of writing her novels. As well as, women as a subject of oppression are always seeking for freedom
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