130,736 research outputs found

    Incidence of Preneoplastic Foci in Rat Liver Dependent on Different Promoting Schemes.

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    After initiation, preneoplastic cell foci emerge in rat liver. They develop differently dependent on promotion, which favors foci incidence with respect to number and size. The process of promotion is dependent on various factors, e.g. the onset and duration of the promotion period (e.g. Deml et al 1981, for literature see: Oesterle and Deml 1983; Deml and Oesterle 1987). In the present experiments, using the rat liver foci bioassay (Oesterle and Deml 1983), the kinetics of development of foci was studied after the application of three different promoting schemes

    Trichotaenia nzingae Oesterle, Serrano & Capela, sp. n.

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    Trichotaenia nzingae Oesterle, Serrano & Capela sp. n. (Figs 1, 2, 3, 6 a) Type series. Holotype, ♂; Angola (BIÉ), 17 km ESE Cachingues (coord.: unknown, 1654 m alt., 281), 16.XI. 2013, DO, A. Oesterle leg., SMNS. Allotype 1 ♀, Paratypes 1 ♂, 1 ♀, Kakande (coord.: 12 º 42´50.73 ´´ S, 16 º 45´33.19 ´´ E, 1716 m alt., 233) (BIÉ), 30.X. 2014, DO, A. Serrano leg., ASC (Allotype 1 ♀, Paratype 1 ♂), MRAC (Paratype 1 ♀); Further paratypes: Angola (BIÉ), 17 km ESE Cachingues (coord.: unknown, 1650 m alt., 281), 16.XI.2013, 2♂, DO, A. Osterle leg., 17.XI.2013, 1♂, 2 ♀, DO, A. Oesterle leg., AOC, Angola (BIÉ), 34 km ESE Cachingues (coord.: unknown, 1650 m alt., 281), 17.XI.2013, 1♀, DO, G. Werner leg., GWC, 18.XI.2013, 2♀, DO, G. Werner leg., GWC and PSC; Angola (BIÉ), 34 km ESE Cachingues (coord.: unknown, 1650 m alt., 281), 17.XI.2013, 1♂, DO, A. Oesterle leg., 18.XI.2013, 6♂, 3 ♀, DO, A. Oesterle leg., AOC. Holotype deposited in the collection of SMNS; Allotype deposited in ASC; Paratypes deposited in AOC (10 ♂, 5 ♀), ASC (1 ♂), GWC (2 ♀), MRAC (1 ♀) and PSC (1 ♀). Derivatio nominis. This species is dedicated to “ Ngola Ana Nzinga Mbande”, known as “Rainha Ginga” also, which was a queen (Ngola) of the kingdoms of Ndongo and Matamba in south‒western Africa in the seventeenth century. The royal title in Kimbundu language, Ngola, was the name used by the Portuguese to name the region (Angola). Diagnosis. A winged Trichotaenia species, black coloured with some slight punctual purpurish and bluish or violet reflections on head, pronotum and elytra. Clypeus mostly setose, blackish with some purpurish blue-greenish reflections. Labrum large, rounded and 5 -toothed in front, variable setose on half posteriad surface with just four marginal sensorial setae, piceous in most specimens, triangularly doubled blackened in the first basal third (males) or triangularly blackened almost in the basal half and part of the apical half (females). A stripe of dense white recumbent pubescence on genae, continuing behind on the ventral half of pro and mesepisterna, on metepisterna up to the lateral sides of first four or five visible abdominal sternites. Sternum, except lateral half of metasternum, and abdominal sternites otherwise glabrous. Antennae attaining nearly the half of the elytral length in male, shorter in female; antennomeres 1-4 dark metallic black with bluish or violaceous reflections, antennomeres 5-10 strongly foliated. Elytral shoulders and part of the disk glabrous. Elytra with decumbent pubescence (Fig. 3) covering the submarginal sides, from the middle of basal third to the apex where it becomes slightly wider and closer to the elytral margin in its apical third, emitting three or sometimes four rami on disc (one slightly arcuate just above the apex, one or two near the middle and a longer one above the middle ascending diagonally to the base of scutellum). A subsutural small elongate tuft of closely appressed setae below the scutellum, sometimes prolonged by sparse setae along the suture. A stripe of setae descending diagonaly between the middle of the anteriad discal ramus and the sutural band, sometimes incomplete. Elytral decumbent pubescence leaving four, sometimes five, naked areoles in between, one subsutural below the appressed setae close to the scutellum, the second one immediately above the middle, the third and larger one below the middle, a fourth one below it and before the apical area, and sometimes a fifth smaller one between the subapical stripe and the lower ramus of the middle stripe. Description. Length of Holotype: 10.3 mm. Length of paratypes (without labrum): 9.2–10.3 mm (males), 10.2–11.4 mm (females). Head (Figs 2 a‒ 2 b). Wider than long (1.4 times) [length: 1.76–2.08 mm (males), 1.95–2.40 mm (females), width 2.76–2.82 mm (males) and 2.85–3.18 mm (females)], with large eyes, slightly narrower than body (Fig. 1), dorsal colour black with coppery reflections; surface sculpture rugulose, rugae forming irregular longitudinal meshes on vertex and transverse meshes on occiput; rugae straight, more or less parallel on orbital plates and frons; occiput, lateral parts of vertex, frons and clypeus sparsely covered with short piceous decumbent setae, temples (lateral area of head behind eyes) indistinctly striaterugulose, glabrous, glossy; a continuous narrow strip in the middle region of vertex and occiput glabrous; genae covered with dense white decumbent pubescence; orbital plates with two sublateral setigerous punctures; labrum large, shape nearly semicircular in both sexes (Figs 2 a‒ 2 b), transverse, wider than long (males: 1.4–1.5 times, females: 1.3–1.4 times), proportionally slightly longer in females [length: 0.90–1.07 mm (males), 1.22–1.44 mm (females), width 1.36–1.54 mm (males) and 1.60–1.92 mm (females)], anterior margin five-toothed, middle basal half slightly protruding, four sublateral sensorial setae, basal and median portions covered with sparse, white decumbent setae (males: 13–53, females: 5–71); colour yellowish with outer margin black, males triangularly doubled blackened in the first basal third, females triangularly blackened almost in the basal half, rarely reaching the anterior margin; antennae reaching the beginning of the median elytral transverse stripe of decumbent setae in male, shorter in female; antennomeres 1–4 dark metallic black with bluish or violaceous reflections, antennomeres 5–10 strongly dilated and foliated, more pronounced in females; mandibles four-toothed, black with large yellow patch basally on outer edge; maxillary and labial palpi light yellow, except terminal palpomeres black with metallic reflections; penultimate palpomere of labial palpus moderately inflated. Thorax. Pronotum (Figs 2 c‒ 2 d) transverse slightly wider than long (1.1 times) [length: 1.68–1.95 mm (males) and 1.79–2.08 mm (females); width: 1.82–2.05 mm (males) and 2.08–2.30 mm (females)], subcordiform-shaped, with the anterior margin slightly larger [width: 1.66–1.84 mm (males) and 1.95–2.11 mm (females)] than the posterior one [width: 1.60–1.79 mm (males) and 1.79–1.92 mm (females)]; black, on each side with a broad sublateral band with cupric reflections, this bands are covered with dense piceous decumbent pubescence, which is transversaly directed on median lobe, oblique on posterior and anterior lobes; along each side of median lobe and on central portions of anterior and posterior lobes a few additional thin piceous setae; surface of pronotum rugulose, rugae forming irregular meshes on latero-dorsal portions, along middle line a narrow band with more transverse-parallel rugae; dorsal half of proepisterna glabrous, ventral half densely covered with white decumbent pubescence which continues that of genae and extends to mesepisterna, metepisterna, lateral portions of metasternum and metacoxae to lateral portions of the first four to five abdominal sterni; proepisterna not visible from above; coupling sulcus: a deeply pitted, funnel-formed impression centrally in upper half of mesepisternum. Elytra (Fig. 3) longer than wide (1.7 –2.0 times) [(length: 5.61–6.47 mm (males) and 6.47–7.06 mm (females); width: 3.01–3.36 mm (males) and 3.58–3.96 mm (females)], subrectangular-shaped, elongated (males) (Figs 3 a–c), more convex and enlarged (females) (Fig. 3 d), shoulders very marked, apex ending in a short but acute sutural spine in both sexes, surface sculptured by coarse, but very densely arranged polygonal (quadrangular to hexagonal) alveoli slight sharply walled, apical margin with distinct microserrulation; posteriad disc near suture not (males) or slightly protruding in relief in its uppermost region (females); colour of elytra black with more or less coppery lustre only in the pubescent areas, otherwise with some bluish or violaceous reflections; Elytra with white-piceous decumbent pubescence, consisting of a submarginal band, from the middle of basal third to the apex where it becomes slightly wider and closer to the elytral margin, anteriad ramus bending inwards towards the base of elytron close to the base of scutellum in the basal third of elytron; this anteriad ramus is sometimes prolonged diagonally in the middle to the subsutural sparse band of setae; the sublateral band emits around or nearly behind the middle a slightly backward straight spur on disc, sometimes divided into two rami (an upper ramus around the middle larger than a lower ramus below the middle, which sometimes can reach the base of the subapical band), and one oblique and slightly arcuate in the apical third of elytron not reaching the suture (sometimes discontinued, forming an isolated discal and more or less circular tuft); parallel to the suture occurs a narrow subsutural band of sparse decumbent setae, beginning near a small elongated tuft of closely appressed setae below the scutellum. Ventral surface. Black, with stronger coppery-golden reflections in head and thorax parts, violet lustre in abdominal sternites; sides of these sternites with decumbent pubescence, except the ultimate or sometimes the ultimate and penultimate ones, becoming sparser towards apex; trochanters black. Legs. Metallic black with greenish reflections in tarsi and violaceous-bluish in femora and tibiae, a few rows of spiniform setae on femora and tibiae; Aedeagus (Fig. 6 a) relatively small (length: 2.56–2.85 mm), arched, tapering, with a straight, simple apex. Intraspecific variation. The range of variability observed in T. nzingae sp. n. (19 specimens) affects the colour and the number of labral decumbent setae (see description) and slightly the elytral decumbent pubescence. The variability within this last character is associated with colour (more or less whitish or piceous) and with minor gaps of setae in the anteriad diagonal band, in the transversal middle band, in the posteriad transversal middle band and in the subapical band (e.g., Figs 3 b‒d). The shapes of pronotum and elytra are very conservative, but variation in the length of the apical denticle of elytra is very common, with individuals having longer denticles than others. Asymmetries in the length of left and right elytron denticles within the same specimen are common too.Published as part of Serrano, Artur R. M., Capela, Rúben A. & Oesterle, Andreas, 2015, Three new species of tiger beetles and new data on Cicindelina species from Angola (Coleoptera: Carabidae: Cicindelinae), pp. 151-178 in Zootaxa 4032 (2) on pages 154-158, DOI: 10.11646/zootaxa.4032.2.1, http://zenodo.org/record/25374

    Learning with interactive animated worked-out examples in groups of two

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    Salle A. Learning with interactive animated worked-out examples in groups of two. In: Allan D, Liljedahl P, Nicol C, Oesterle S, eds. Proceedings of the 38th Conference of the International Group for the Psychology of Mathematics Education. Vol 5. Vancouver, Canada: PME; 2014: 81–88

    Kitsch als eine Bedingung der Möglichkeit von romantischer Kunst?

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    Grave J. Kitsch als eine Bedingung der Möglichkeit von romantischer Kunst? In: von Graevenitz G, Hinderer W, Neumann G, Oesterle G, von Wietersheim D, eds. Romantik kontrovers. Stiftung für Romantikforschung. Vol 58. Würzburg: Königshausen und Neumann; 2015: 93-105

    MeSH term explosion and author rank improve expert recommendations

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    Information overload is an often-cited phenomenon that reduces the productivity, efficiency and efficacy of scientists. One challenge for scientists is to find appropriate collaborators in their research. The literature describes various solutions to the problem of expertise location, but most current approaches do not appear to be very suitable for expert recommendations in biomedical research. In this study, we present the development and initial evaluation of a vector space model-based algorithm to calculate researcher similarity using four inputs: 1) MeSH terms of publications; 2) MeSH terms and author rank; 3) exploded MeSH terms; and 4) exploded MeSH terms and author rank. We developed and evaluated the algorithm using a data set of 17,525 authors and their 22,542 papers. On average, our algorithms correctly predicted 2.5 of the top 5/10 coauthors of individual scientists. Exploded MeSH and author rank outperformed all other algorithms in accuracy, followed closely by MeSH and author rank. Our results show that the accuracy of MeSH term-based matching can be enhanced with other metadata such as author rank

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Accelerating junior-secondary mathematics

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    Unfortunately, in Australia there is a prevalence of mathematically underperforming\ud junior-secondary students in low-socioeconomic status schools. This requires targeted\ud intervention to develop the affected students’ requisite understanding in preparation\ud for post-compulsory study and employment and, ultimately, to increase their life\ud chances. To address this, the ongoing action research project presented in this paper is\ud developing a curriculum of accelerated learning, informed by a lineage of\ud cognitivist-based structural sequence theory building activity (e.g., Cooper & Warren,\ud 2011). The project’s conceptual framework features three pillars: the vertically\ud structured sequencing of concepts; pedagogy grounded in students’ reality and culture;\ud and professional learning to support teachers’ implementation of the curriculum\ud (Cooper, Nutchey, & Grant, 2013). Quantitative and qualitative data informs the\ud ongoing refinement of the theory, the curriculum, and the teacher support

    "Closing the R&D Gap, Evaluating the Sources of R&D Spending"

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    Both spending and tax policies have been implemented in the United States with the goal of stimulating private sector research and development (R&D). Karier questions whether current R&D policy, especially the research and experimentation tax credit, can contribute to closing the gap between nondefense expenditures on R&D in the United States and such expenditures in other countries, such as Japan and Germany. He also explores possible changes to our current R&D policy to make it more effective.

    A. D. Fricke, author

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    Black and white photograph of author, A. D. Fricke

    Dispelling the Myths Behind First-author Citation Counts

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    We conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more sophisticated methods
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