1,204 research outputs found

    Rev. Perry C. Bramlett Collection

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    Finding aid of the Rev. Perry C. Bramlett manuscript collectionA graduate of Southern Seminary in Louisville, Kentucky; a noted author; and a dedicated and respected scholar, Rev. Perry C. Bramlett�s life work was taking C. S. Lewis to the local church. His widow, Joan Fine Bramlett of Fairhope, Alabama, selected Mercer University to house this collection to honor Bramlett�s work, to share the significance of Bramlett�s life, and to mark his contributions to the scholarship of C. S. Lewis and his friends and their influences

    Commentary: Water: A Preventable Disaster

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    Editor-in-Chief\u27s Note: The Texas Water Journal invited Texas state Senator Charles Perry, Chair of the Senate Committee on Water and Rural Affairs, to share his thoughts on the role of water in the coming 87th legislative session of the Texas Legislature. In the upcoming legislative session, Senator Perry said Texas will be navigating the continuing COVID-19 pandemic, the road to recovery and continuing water supply development. In the commentary, Senator Perry addresses how leveraging technology, public-private partnerships, and regulations will encourage the creation of new water sources while also expanding existing strategies. The opinion expressed in this commentary is the opinion of the individual author and not the opinion of the Texas Water Journal or the Texas Water Resources Institute. Citation: Perry C. 2020. Commentary: Water: A Preventable Disaster. Texas Water Journal. 11(1):172-173. Available from: https://doi.org/10.21423/twj.v11i1.7129

    Commentary: Water Fuels Our Future

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    Editor-in-Chief\u27s Note: The opinion expressed in this commentary is the opinion of the individual author and not the opinion of the Texas Water Journal or the Texas Water Resources Institute. Citation: Perry C. 2019. Commentary: Water Fuels Our Future. Texas Water Journal. 10(1):22-23. Available from: https://doi.org/10.21423/twj.v10i1.7091

    Correspondence from Francine Perry and J. C. Fauntleroy to Vernon Jordan, April 1966

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    Correspondence from Francine Perry and J. C. Fauntleroy to Vernon Jordan. Enclosed is "A Background Report on the Newport News-Hampton SMSA for the Participants of the NAACP-National Student YWCA Project" written by Herbert H. Lindsay

    Change in tau phosphorylation associated with neurodegeneration in the ME7 model of prion disease

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    Hyperphosphorylation of the microtubule-associated protein tau is a significant determinant in AD (Alzheimer's disease), where it is associated with disrupted axonal transport and probably causes synaptic dysfunction. Although less well studied, hyperphosphorylation has been observed in prion disease. We have investigated the expression of hyperphosphorylated tau in the hippocampus of mice infected with the ME7 prion agent. In ME7-infected animals, there is a selective loss of CA1 synapse, first discernable at 13 weeks of disease. There is a potential that dysfunctional axonal transport contributes to this synaptopathy. Thus investigating hyperphosphorylated tau that is dysfunctional in AD could illuminate whether and how they are significant in prion disease. We observed no differences in the levels of phosphorylated tau (using MC1, PHF-1 and CP13 antibodies) in detergent-soluble and detergent-insoluble fractions extracted from ME7- and NBH- (normal brain homogenate) treated animals across disease. In contrast, we observed an increase in phospho-tau staining for several epitopes using immunohistochemistry in ME7-infected hippocampal sections. Although the changes were not of the magnitude seen in AD tissue, clear differences for several phospho-tau species were seen in the CA1 and CA3 of ME7-treated animals (pSer(199-202)>pSer(214)>PHF-1 antibody). Temporally, these changes were restricted to animals at 20 weeks and none of the disease-related staining was associated with the axons or dendrites that hold CA1 synapses. These findings suggest that phosphorylation of tau at the epitopes examined does not underpin the early synaptic dysfunction. These data suggest that the changes in tau phosphorylation recorded here and observed by others relate to end-stage prion pathology when early dysfunctions have progressed to overt neuronal loss

    A calm and peaceful land

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    UPEI 091; [sound recording] / P. Batchilder, M. Hennessey, C. Perry.; 2 sound cassettes (125 min.; Contents : Introductions (Grant & Robb) -- The Belfast riots (Batchilder) -- "The artist" (Hennessey) -- Rum running days (Perry).; Introduction : William Grant ; Andy Robb.; Recorded at the Confederation of the Arts Centre, 13 March 1977.; The Belfast riotsSource type: Electronic(1

    George Perry (c.1718-1771): industrialist, cartographer and naturalist

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    George Perry (c.1718–1771) is known for his involvement in the development of the iron and engineering industries of Coalbrookdale, Ironbridge Gorge, Shropshire and Liverpool, and also for his ambition to publish a history together with new maps of Liverpool. In 1758, Perry’s best known work, A description of Coalbrookdale in the County of Salop, with two perspective views thereof was published. The aforementioned views, produced in collaboration with Thomas Smith of Derby (1720–1767), are two of the earliest examples of industrial landscapes. Perry also pursued interests in geology and natural history. He maintained a correspondence and exchanged specimens of fossils with, among others, Emanuel Mendes da Costa (1717–1791), Thomas Pennant (1726–1798) and Gustavus Brander (c.1719–1787). His work on the history of Liverpool was absorbed into An essay towards the history of Leverpool drawn up from papers left by the late Mr. George Perry, and from other materials since collected by William Enfield (1773). His son, George Perry (1771–1823), was the author of Conchology, or the natural history of shells (1811). We record Perry’s busy life and career and attempt to give due weight to his several different interests

    Northwest Perry Child Development Center, 1969

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    The following proposal entitled Northwest Perry Child Development CenterIs submitted to the United States Office of Health, Education, and Welfare, office of Economic Opportunity. The project has been designed for a one year period, under the direction of Mrs. Odinga Dalrobl, This project is requesting funds in the amount of $11,900.00. There will be eleven pro�fessional full-time staff members, three part-time professional and eleven non-professionals. The project will run from Sep�tember 1, 1969 to August 31. 1970.The proposed child Development Center will meet an acute need for day care in the Northwest Perry area in Atlanta, Georgia where no child care facility exists for low-income families. The center would serve fifty children from three to twelve years of age, freeing low-income mothers and fathers for the employ�ment market, between the hours of 7:00 A.M. and 12:00 midnight.There have been several attempts of welfare recipients and other low-income families to become self-sufficient through employment. Because they are unskilled, many are participating in re-training programs. Others must take jobs at night. What happens to their children during these hours or after they are dismissed from school? This project is worthy of support, because, children will receive the educational, social, and emotional attention due them through knowledgeable, and skilled professional workers. Children of school age will be able to receive free tutoring services in areas where educational weaknesses have been de�tected. This service will be provided by volunteer students and graduates from the Atlanta University Center. Child care which affords maximum opportunity to grow and develop, provides planned and well prepared meals, and assures exceptional physical care of children is the first priority of service given by the child development center, which is here proposed

    Commentary: Water Infrastructure and Supply Are the Backbone or Achilles’ Heel of Texas’ Future: The Choice is Ours

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    Editor-in-Chief\u27s Note: In every odd-numbered year, the Texas Legislature convenes in regular session for 140 days. With this in mind, the Texas Water Journal invited Senator Charles Perry, Chairman of the Senate Water, Agriculture, and Rural Affairs Committee to discuss his priorities and visions for Texas water and the regular session of the 88th Texas Legislature. The opinion expressed in this commentary is the opinion of the individual author and not the opinion of the Texas Water Journal or the Texas Water Resources Institute, or the Bureau of Economic Geology

    George Perry (1771–1823): architect and naturalist

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    George Perry (1771-1823) was an artist, architect and sculptor, with a deep interest in natural history and malacology. (His father, George Perry (c.1718-1771), was a pioneering industrialist, with a particular interest in geology and also the history of Liverpool.) He was the co-author (with John Corry) of The History of Liverpool (1807). He gave lectures on natural history and mineralogy and earned a living as an architect and sculptor. After bankruptcy in Liverpool in 1807, Perry re-established himself in London. There he published two books - A descriptive catalogue of the pictures in the collection of the Marquis of Stafford in London (1807) and Conchology, or the natural history of shells (1811). He also published the serial publication entitled Arcana, or, the Museum of Natural History (1810-1811). After this, he disappeared from the public record until his death in Chelsea in 1823. His life and his contributions to natural history are summarized here
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