106,274 research outputs found
Notes on Dineutus helleri Ochs, 1925, with new records for the Cyclops Mountains Whirligig Beetle, Dineutus h. stueberi Ochs, 1955 (Coleoptera, Gyrinidae)
We review Dineutus helleri Ochs, 1925, a whirligig beetle species endemic to New Guinea’s north coast mountains. Its diagnostic characters are illustrated for easy species identification. We provide a summary and geographic interpretation of historical records, provide new records and, for the first time, habitat photographs for the subspecies D. h. stueberi Ochs, 1955, which is endemic to the Cyclops Mountains area. We also discuss the subspecies classification of this species
"Conflict or Cooperation? Transatlantic Relations in the Environmental Field1"
[From the Introduction]. The US withdrawal from the Kyoto Protocol has brought transatlantic differences over environmental issues into the headlines. Since then, climate change politics has been referred to as a prominent example for the development of a transatlantic rift. However, transatlantic differences over environmental policy are anything but new. Many of these conflicts just have been hidden from public view as they are often concerned with technical aspects of regulation and negotiated on the staff level. This paper discusses three recent examples of transatlantic conflict over environmental policy. Climate change, environmental standards for export credit agencies (ECAs), and regulation of genetically modified organisms (GMOs) have all proven to be significant sources of transatlantic divergences. This is primarily the case because these topics are not purely environmental issues, but rather cross-cutting policy challenges with substantial impacts on a number of policy areas. These topics entail both complex cost-benefit-assessments and coordination among different domestic and foreign policy bureaucracies. In order to protect the earth’s ecosystem, climate change policy calls for adjustments in energy production, transport, infrastructure, industry and economics; climate change, however, also poses critical questions regarding North-South relations, inter-generational equity, and the future of the capitalist system. Likewise, international environmental standards for ECAs do not only address ecological concerns in international investment decisions, they also create a level playing field for international competition. Finally, the regulation of GMOs aims at minimizing the risks of biotechnology for humans and their environment; at the same time, however, regulations can become non-tariff barriers to trade
Occurence of lipid bodies in canine type II pneumocytes during hypothermic lung ischemia
Type II pneumocytes defend the pulmonary alveolus by synthesis and secretion of surfactant and by contributing to alveolar epithelial regeneration. Lipid bodies are regarded as intracellular domains for the synthesis of eicosanoid mediators that can be induced by inflammatory stimuli. The aim of the present study was to establish whether hypothermic ischemic lung storage without further preservation measures leads to an induction of lipid body formation in canine type II pneumocytes. The lungs of 18 dogs were fixed for transmission electron microscopy (TEM) immediately after cardiac arrest (six double lungs) and after ischemic storage in Tutofusin solution at 4degreesC for 20 min, 4 hr, 8 hr, and 12 hr (six single lungs, respectively). Type II pneumocytes were analyzed qualitatively by conventional TEM (CTEM) and quantitatively by stereology. The relative phosphorus content of surfactant containing lamellar bodies, lipid bodies, and intermediate forms was investigated by energy-filtering TEM (EFTEM). By CTEM, lipid bodies as well as forms intermediate between lipid bodies and lamellar bodies were already noted in the control group but were more pronounced in the ischemia groups. Beginning at 20 min of ischemic storage, a significant increase in the volume density of lipid bodies was noted in the ischemic groups as compared to the control group. By EFTEM, the highest intracellular phosphorus signals were recorded over lamellar bodies and lamellar areas of intermediate forms in all experimental groups, while lipid bodies and homogeneous areas of intermediate forms did not show a clear phosphorus signal. These results indicate that the formation of lipid bodies in canine type 11 pneumocytes is induced early during ischemic lung storage. (C) 2004 Wiley-Liss, Inc
Ms. Ff. J. Ch. Ochs v. Ochsenstein - Alltägliches Morgengebät mein
Vorbesitzer: Johann Christoph Ochs von Ochsenstein; alte Signatur: Ms.Ff.Ochs 1;die Paginierung geht nur bis S. 450; zusätzlich gibt es die Seiten 110a-h, 234a und 235a
Ultrastructure of canine type II pneumocytes during hypothermic ischemia of the lung: A study by means of conventional and energy filtering transmission electron microscopy and stereology
Alterations in pulmonary surfactant have been reported to be associated with ischemia/reperfusion injury in experimental and clinical lung transplantation. It is unknown whether these alterations are due to damage to surfactant synthesizing type II pneumocytes during hypothermic ischemic storage. The aim of the present study was to examine the effects of hypothermic ischemic storage of the lung on canine type II pneumocytes by means of conventional (CTEM) and energy filtering TEM (EFTEM) and stereology. The lungs of 18 dogs were fixed for TEM immediately after cardiac arrest (6 double lungs) and after storage in Tutofusin(R) at 4 degreesC for 20 min, 4 hr, 8 hr, and 12 hr (6 single lungs, respectively). Using a systematic uniform random sampling scheme, type II pneumocytes were analyzed qualitatively and stereologically. The relative phosphorus content of cell organelles, especially the surfactant, containing lamellar bodies, was investigated by EFTEM. By CTEM, no major qualitative alterations could be observed in type II pneumocytes of the experimental groups. Stereologically, no significant changes in the volume densities or the volume-to-surface ratios of type II pneumocytes and their lamellar bodies were found. By EFTEM, the highest intracellular phosphorus signals were recorded over lamellar bodies in all experimental groups. No changes in the phosphorus signals were observed during ischemia. These results indicate that the ultrastructure of canine type II pneumocytes and their lamellar bodies is not affected by hypothermic ischemia of the lung up to 12 hr. Structural preservation of intracellular surfactant is possible during prolonged ischemic lung storage. Anat Rec 263:118-126, 2001. (C) 2001 Wiley-Liss, Inc
Überlegungen und Forschungen zur geschichtswissenschaftlichen Hochschullehre
Frings A, Korbel S, Neumann F, Ochs H. Überlegungen und Forschungen zur geschichtswissenschaftlichen Hochschullehre. Geschichtswissenschaftsdidaktik. 15.10.2021
Supplemental Material, ExampleQuestionnaire - Tracking Children’s Mental Health in the 21st Century: Lessons from the 2014 OCHS
Supplemental Material, ExampleQuestionnaire for Tracking Children’s Mental Health in the 21st Century: Lessons from the 2014 OCHS by Michael H. Boyle, Laura Duncan, Katholiki Georgiades, Jinette Comeau, Graham J. Reid, Warren O’Briain, Robert Lampard, Charlotte Waddell and 2014 Ontario Child Health Study Team in The Canadian Journal of Psychiatry</p
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Involvement of cathepsin H in the processing of the hydrophobic surfactant-associated protein C in type II pneumocytes
Surfactant protein C (SP-C) is synthesized by type 11 pneumocytes as a 21-kD propeptide (proSP-C) which is proteolytically processed to a 4.2-kD dipalmitoylated protein. To characterize the processing of proSP-C and the role of the cysteine protease cathepsin H, we studied the localization of proSP-C and cathepsin H in human as well as proSP-C in rat lungs, the enzymatic cathepsin H activity in isolated rat lamellar bodies, and the cleavage of human proSP-C by purified cathepsin H. Using antisera directed against the N-terminal E-11-R-23 (NPROSP-C11-23), the C-terminal G(162)-G(174) domain (CPROSP-C162-174) of proSP-C, and against cathepsin H, immunogold labeling identified all three in electron-dense multivesicular bodies, but only NPROSP-C11-23 and cathepsin H in composite as well as lamellar bodies of type 11 pneumocytes. Immuno double-labeling further distinguished electron-dense vesicles containing cathepsin H or electron light vesicles/multivesicular bodies containing proSP-C. Isolated lamellar bodies contained enzymatically active cathepsin H, a 6-kD proSP-C processing intermediate detected only by NPROSP-C11-23, and mature SP-C. Using enzyme activities comparable to those in isolated lamellar bodies, purified cathepsin H generated a partially N-terminal processed proSP-C intermediate in vitro. In conclusion, our results indicate that after the fusion of electron-dense vesicles containing cathepsin H and electron-light vesicles or multivesicular bodies containing proSP-C, cathepsin H is involved in the first N-terminal processing step of proSP-C in electron-dense multivesicular bodies of type 11 pneumocytes.PHS HHS [P01-19737
- …
