1,720,974 research outputs found
COMPARATIVE INVITRO ACTIVITY OF NORFLOXACIN (MK-0366) AGAINST GRAM-NEGATIVE BACILLI ISOLATED FROM URINARY-TRACT INFECTIONS
No full textEFFECT OF JOSAMYCIN ON PHAGOCYTE AND MICROBICIDIC FUNCTIONS OF HUMAN POLYMORPHONUCLEAR CELLS
No full textCLINICAL-EVALUATION OF PIPERACILLIN IN THE TREATMENT OF SEVERE INFECTIONS IN OBSTETRICS AND GYNECOLOGY
No full textINFECTIONS IN THE SURGICAL SETTING - EPIDEMIOLOGY AND EFFECT OF TREATMENT WITH CEFOTAXIME IN A MULTICENTER TRIAL INCLUDING 3,032 PATIENTS
No full textHospital-acquired infections still represent a serious threat to the surgical patient. A nationwide survey of 259 Italian surgical wards involving 11,343 patients was conducted in October 1988. Hospital-acquired infections were recorded in 565 (5%) patients: the microorganisms most commonly involved were gram-negative rods (60% of all isolates), 41% of the infected patients presented one or more intrinsic predisposing factor, and 65% had undergone some invasive procedure. The studied group represented 23% of all surgical patients in the country on the days of the survey. Following the epidemiologic survey, an open multicenter study was conducted in the same wards to evaluate the efficacy and tolerability of cefotaxime (1 g, 2 or 3 times per day) in the treatment of nosocomial surgical infections. Among 3,032 evaluable patients, 1,295 intra-abdominal, 610 wound and soft tissue, 554 urinary, and 367 respiratory infections were observed. Treatment was judged to be clinically effective in 94% of patients, and side effects, mostly involving the gastrointestinal tract, were observed in 1.4% of patients; hut interruption of the treatment was required only in 19 patients (0.6%). This study confirms that cefotaxime, after over a decade of use, retains high efficacy in the treatment for nosocomial infections and induces a low rate of side effects
HIGH HOMOLOGY OF MEMBRANE-PROTEINS ELECTROPHORETIC PATTERN IN BACTEROIDES-FRAGILIS AS CONFIRMED BY VARIOUS SOLUBILIZING METHODS
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Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
A multicenter study on the prevalence of resistance to broad-spectrum cephalosporins among Enterobacteriaceae in Italy. J. Clinical Microbiology and Infection
No full textPROSPECTIVE-STUDY OF CLOSTRIDIUM-DIFFICILE INTESTINAL COLONIZATION AND DISEASE FOLLOWING SINGLE-DOSE ANTIBIOTIC-PROPHYLAXIS IN SURGERY
No full textA total of 108 volunteers undergoing an elective surgical procedure were randomly given a single 2-g intravenous prophylactic dose of either a cephalosporin or mezlocillin. Stool samples were cultured for Clostridium difficile the day before the operation and later on postoperative days 4, 7, and 14. C. difficile was detected in 23.0% of patients who received a cephalosporin (cefoxitin, 8.3%; cefazolin, 14,3%; cefotetan, 20.0%; ceftriaxone, 25.0%; cefoperazone, 43.7%), in 3.3% of patients given mezlocillin, and in none of 15 control volunteers given no antimicrobial agent. No patient experienced diarrhea
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