42 research outputs found
Oyedeji, Adebola, O
No full textTitle: Professor of Organic Chemistry ORCID: 0000-0001-8765-7766 Faculty of Natural Sciences, Department of Chemical and Physical Sciences Qualification * PhD Organic Chemistry Expertise * Natural Product Chemistry (Essential Oil Researches) My site https://www.researchgate.net/profile/Adebola_Oyedeji2 List of Publications: 1. Oyedeji OA, Ekundayo O, Mekem Sonwa M, Fricke C, Koenig WA (1998): Isolation and structural elucidation of (-)-Eudesma-1,4(15),11-triene from the essential oil of Callitris intratropica. Phytochemistry, 48, 657-660. 2. Oyedeji OA, Ekundayo O, Koenig WA (1999): Constituents of the essential oil from the leaves of Leonotis nepetafolia. Journal Essential Oil Research, 11, 716-718. 3. Oyedeji OA, Olawore ON, Ekundayo O, Koenig WA (1999): Volatile leaf oil constituents of three Eucalyptus species from Nigeria. Flavour and Fragrance Journal, 14, 241-244. https://doi.org/10.1002/(SICI)1099-1026(199907/08)14:43.0.CO;2-Y 4. Oyedeji OA, Ekundayo O, Olawore ON, Adeniyi BA, Koenig WA (1999): Antimicrobial activity of the essential oils of five Eucalyptus species growing in Nigeria. Fitoterpia, 70, 526-528. 5. Oyedeji OA, Ekundayo O, Olawore ON, Koenig WA (2000): Essential oil composition of two varieties of Eucalyptus camaldulensis from Nigeria. Journal Essential Oil Research, 12, 102-104. 6. Kasali AA, Oyedeji OA, Ashilokun OA (2001): Volatile leaf oil constituents of Cymbopogon citratus (DC) Stapf. Flavour and Fragrance Journal, 16, 377-378. 7. Oyedeji OA, Ekundayo O, Koenig WA (2002): Volatile constituents of Clerodendron captatium L. leaves. Journal of Essential Oil Bearing Plants, 5 (1), 8-13. 8. Oyedeji OA, Ekundayo O, Koenig WA (2002): Essential oil Composition of Lawsonia inermis L. from Nigeria. Flavour and Fragrance Journal, 18, 384-386. https://doi.org/10.1080/10412905.2005.9698943 9. Kasali AA, Ekundayo O, Oyedeji OA, Adeniyi B, Eshilokun OA (2002): Antimicrobial activity of Lantana camara essential oil. Journal of Essential Oil Bearing Plants, 5 (2), 108-110. 10. Kasali AA, Adewale MA, Oyedeji OA, Eshilokun OA, Adefenwa M (2002): Volatile constituents of Boswellia serratra Bark Roxb. (Fam. Burseraceae). Flavour and Fragrance Journal, 17, 462-464. https://doi.org/10.1002/ffj.1124 11. Kasali AA, Adewale MA, Ekundayo O, Oyedeji OA, Eshilokun OA, Adefenwa M, Adeniyi BA (2002): Antimicrobial activity of Boswellia serratra Bark essential oil Roxb. (Fam. Burseraceae). Journal of Essential Oil Bearing Plants, 5 (3), 173-175. 12. Oyedeji OA, Ekundayo O, Koenig WA (2003): Volatile leaf oil of Lantana camara L. from Nigeria. Flavour and Fragrance Journal, 18, 384-386. 13. Afolayan AJ, Oyedeji OA, Sultana N (2004): Phytomedical investigation of Arctotis arctotoides: a herb used for the treatment of various diseases in the Eastern Cape, South Africa. The Zambian Journal of Science and Technology, 1(1), 2-6. 14. Oke OA, Afolayan AJ, Oyedeji OA (2004): Validation of the antimicrobial potential of Anacardium occidentale and Calitropics procera against cough symptoms. Nigeria Journal of Research and Review in Science, 4, 56-60. 15. Oyedeji OA, Yani VV, Afolayan AJ (2005): Chemical composition of the essential oil from Arctotis arctotoides (L. F) O. Hoffm. (sym Vendium arctotoides Less. Flavour and Fragrance Journal, 20, 232-234 16. Oke OA, Oyedeji OA, Afolayan AJ (2005): Validation of the antimicrobial property of some plants commonly used for mouth infections in South-West Nigeria. Phytotherapetics of the Series Recent Progress in Medicinal Plants, 10, 163-168. 17. Oyedeji OA, Afolayan AJ (2005): Comparative study of the essential oil composition and antimicrobial activity of Leonotis leonurus and L. ocymifolia in the Eastern Cape, South Africa. South African Journal of Botany, 71, 114-116. 18. Oyedeji OA, Ekundayo O, Koenig WA (2005): Leaf essential oil of Lawsonia inermis (syn. L. alba) Linn. Journal of Essential Oil Research, 17, 403-404. 19. Oyedeji OA, Ajayi A, Adeniyi B, Koenig WA (2005): Essential oil composition of Piper guineense and its antimicrobial activity. A new chemotype from Nigeria. Phytotherapy Research, 19, 362-364. 20. Yani VV, Oyedeji OA, Grierson D, Afolayan AJ (2005): Chemical analysis and antimicrobial activity of essential oil extracted from Helichrysum aureonitens. South African Journal of Botany, 71, 239-241. 21. Oyedeji OA, Afolayan AJ (2005): Chemical composition and antibacterial activity of the essential oil of Centella asiatica growing in South Africa. Journal of Pharmaceutical Biology, 43, 249-252. 22. Oyedeji OA, Afolayan AJ (2006): Chemical composition and antibacterial activity of the essential oil isolated from South African Mentha longifolia (L.) L. subsp. capensis (Thunb.) Briq. Journal of Essential Oil Research, 18, 57-59. 23. Oke OA, Afolayan AJ, Oyedeji OA (2006): Authentication of antimicrobial properties of two plants commonly used against gastrointestinal infection. Nigerian Journal of Botany. 24. Moronkola DO, Oyedeji OA, Ekundayo O and Ogunbinu OA (2006): Composition of the root essential oil of Chrysophyllum albidum G.Don. Bowen J. of Agric., 3, 53-58. 25. Asekun OT, Ekundayo O and Oyedeji AO (2007): The volatile constituents of the leaves and flowers of Kigelia african Benth. Flavour and Fragrance J., 22, 21-23. 26. Oyedeji OA, Lawal OA, Adeniyi BA, Alaka SA and Tetede E (2008): Essential Oil Composition of Three Zanthoxylum Species. Journal of Essential Oil Research, 20, 69-70. 27. Mdlolo CM, Shandu JS and Oyedeji OA (2008): Phtyochemical constituents and Antimicrobial Studies of Two South African Phyllanthus Species. African Journal of Biotechnology, 7, 639-643. 28. Odeleye MO and Oyedeji OA (2008): Antimicrobial activities of crude and fractions of Momordica foetida leave extract. International Journal of Biomedical and Pharmaceutical Science, 2, 75-78. 29. Oyedeji OO, Lawal OA, Shode FO and Oyedeji OA (2009) Chemical Composition and antibacterial activity of the essential Oils of Callistemon citrinus and Callistemon viminalis from South Africa. Molecules, 14, 1990-1998. 30. Lawal OA and Oyedeji OA (2009) Chemical composition of the essential oils of the flowers, leaves and stems of two Senecio polyanthemoides Sch. Bip. from South Africa. Molecules, 14, 2077-2086. 31. Oyedeji OA, Afolayan JA, and Hutchings A (2009) Compositional Variation of the Essential Oils of Artemisia afra Jacq. from three Provinces in South Africa - A Case Study of its Safety. Natural Product Communications, 4, 749-888 32. Lawal OA and Oyedeji OA (2009) Chemical Composition of the Essential Oils of Cyperus rotundus L. from South Africa. Molecules, 14, 2909-2917. 33. Lawal OA and Oyedeji OA (2009) The Composition of the Essential Oil from Cyperus distans L.f. Rhizome. Natural Product Communications, 4, 1099-1102. 34. Odeleye MO and Oyedeji AO (2009) Antimicrobial activity of pentacyclic triterpenes isolated from Berkheya bergiana. Planta Medica, 2009; 75 - PD80 DOI: 10.1055/s-0029-1234559 35. Oyedeji OA, Mdlolo CM, Adeniyi BA and Akinde T (2010) 1,8-Cineole Chemotype of the Essential Oils of Kyllinga erecta Schum & Thonn and its Antimicrobial Activities. Journal of Essential Oil Research, 22, 189-192. 36. Oyedeji OA, Oyedeji OO, Adeniyi BA, Alaka SA and Tetede E (2010) Antimicrobial Potential of Three Zanthoxylum Species against Genitourinary Tract Pathogens. Journal of Essential Oil Bearing Plants, 13, 496-502 37. Lawal OA, Oyedeji OA and Hutchings A (2010) Chemical composition of the Leaf Oil of Plectranthus neochilus Schltr. Journal of Essential Oil Research, 22, 546-547 38. Oyedeji OO, Lawal OA, Shode FO and Oyedeji OA (2010) Volatile Constituents of the leaf oils of Callistemon salignus from Two Provinces in South Africa. Journal of Essential Oil Research, 22, 613-615 39. Lawal OA and Oyedeji OA (2010) Volatile Constituents of Senecio pterophorus (African Daisy) DC. from South Africa. Natural Product Communications, 5, 1711-1814. 40. McEwan R, Madivha RP, Djarova T, Oyedeji OA, Opoku, AR (2010) Alpha-amalyase inhibitors of amadumbe (Colocasia esculenta): Isolation, purification and selectivity towards a-amylases from various sources. African Journal of Biochemistry Research, 4, 220-224. 41. Mosa RA, Lazarus GG, Gwala PE, Oyedeji AO, Opoku AR (2011) In Vitro anti-platelet aggregation, antioxidant and cytotoxic activity of extract of some Zulu medicinal Plants. Journal of Natural Product, 4, 136-146 42. Peebles J, Gwebu E, Oyedeji O, Setzer W, Nanyonga S, Kunene N, Oyedeji A (2011) Essential Oil Composition of Thelechitonia trilobata (L.) H. Rob. & Cuatrec Growing in South Africa and its Biological Potential. Natural Product Communication, 6, 1799-1968. 43. Mosa RA, Oyedeji AO, Shode FO, Singh M, Opoku AR (2011) Triterpenes from isolated from the stem bark of Protorhus longifolia exhibit anti-platelet aggregation activity. Pharmaceutical Biology, 24, 2698-2714. 44. Olukayode MO, Oyedeji AO., Opoku AR (2011) Anitmicrobial Activity of Berkheya bergiana leaves extracts. African Journal of Biotechnology 10 (24), 4941-4946. 45. Nanyonga SK, Opoku A, Lewu FB, Oyedeji AO (2012) Chemical composition and larvicidal activity of the essential oil of Tarchonanthus camphoratus against Anopheles arabiensis mosquito larvae. Journal of Essential Oil Bearing Plants, 15, 288-289. 46. Lawal OA, Adeleke AK, Opoku AR, Oyedeji AO (2012) Volatile constituents of the flowers, leaves, stems and roots Tithonia diversifolias (Hemsely) A. Gray. Journal of Essential Oil Bearing Plants, 15, 816-821. 47. Morobe IC, Mthethwa NS, Obi CL, Oyedeji AO, Vasaikar SD, and Hattori T, (2012) Cytotoxic and safety profiles of extracts of active medicinal plants. Journal of Microbiology Research, 2,176 -182. 48. Morobe IC, Mthethwa NS, Obi CL, Oyedeji AO, Vasaikar SD, Hattori T, (2013) Prevalence, and antibiotic profiles of S. pneumoniae and H. influenzae isolated from clinical samples of patients in Mthatha, Eastern Cape, South Africa. Journal of Microbiology Research, 3, 57-65. 49. Soyingbe OS, Oyedeji AO, Basson AK, Opoku AR, (2013) The essential oil of Eucalyptus grandis W. Hill ex Maiden inhibits microbial growth by inducing membrane damage.). A. Gray. Chinese Medicine, 4, 7-14. 50. Nanyonga SK, Opoku AR, Lewu FB, Oyedeji AO, Singh M (2013). Chemical composition, antioxidant activity and cytotoxicity of essential oil of leaves and stem of Tarchonanthus camphoratus. African Journal of Pharmacy and Pharmaceutical, 7, 360-367. 51. Ajibade PA, Zulu NH, Oyedeji AO (2013) Synthesis, characterization and antibacterial studies of some metal complexes of dialkyl thiourea: The X-Ray single crystal structure of [CoCl2(detu)2]. Synthesis and Reactivity in Inorganic, Metal-organic, and Nano-Metal Chemistry, 43, 1-8. 52. Nanyonga SK, Opoku AR, Lewu FB, Oyedeji AO (2013). Variation in chemical composition, antibacterial activity of the essential oil of fresh and dry leaves and dry stem of Tarchonanthus camphoratus. Journal of Medicinal Plants Research, 7, 442-447. 53. Soyingbe OS, Oyedeji AO, Basson AK, Singh M, Opoku AR, (2013) Chemical composition, antimicrobial and anxtioxidant properties of the essential oils of Tulbaghia violacea Harv L.F. African Journal of Microbiology Research, 7, 1787-1793. 54. Nanyonga SK, Opoku AR, Lewu FB, Oyedeji OO, Oyedeji AO (2013). Phytochemical Constituents, Antioxidant Activity and Cytotoxicity of Various Extracts of the Dried Leaf and Bark of Tarchonanthus camphoratus. Tropical Journal of Pharmaceutical Research, 12(3), 377-383. 55. Oyedeji OO, Shode FO, Oyedeji OA (2014) Compositional variations of the Essential Oils of three Melaleuca Species from South Africa. Journal of Essential Oil Bearing Plant, 17(2), 265-276. 56. Oyedeji OO, Shode FO, Oyedeji AO, Songca SP, Gwebu ET, Hill GM, Setzer WN. (2014) Semi-synthesis of Nitrogen Derivatives of Oleanolic Acid and Effect on Breast Carcinoma MCF-7 Cells. Anticancer Research, 34(8):4135-9. 57. Morobe, IC, Obi, CL, Oyedeji, AO, Vasaikar, SD, Wale BK, (2014). The genetic landscape of isolates of H. influenzae and S. pneumoniae from Mthatha in the Eastern Cape Province, South Africa. Journal of Microbiology, 3(4): 59-77. 58. Lawal OA, Ogunwande IA, Opoku AR, Kasali AA, Oyedeji AO (2014) Chemical Composition and Antibacterial Activities of Essential Oil of Warburgia salutaris (Bertol. f.) Chiov. from South Africa. Journal of Biologically Active Products from Nature, 4(4), 272-277, DOI: 10.1080/22311866.2014.936908 59. Oyemitan IA, Kolawole F and Oyedeji AO (2014) Acute toxicity, antinociceptive and anti-inflammatory activity of the essential oil of fresh fruits of Piper guineense Schum &Thonn (Piperaceae) in rodents. Journal of Medicinal Plant Research, 8, 1191-1197. 60. Mthethwa NS, Oyedeji AO, Obi LC, Aiyegoro AO (2014) Anti-Staphylococcal, Anti-HIV and Cytotoxicity Studies of four South African Medicinal Plants and Isolation of Bioactive Compounds from Cassine transvaalensis (Burtt. Davy) Codd. BMC Complementary and Alternative Medicine 14:512 – 523. 61. Nanyonga SK, Opoku AR, Lewu FB, Oyedeji AO (2015) Insecticidal activities and chemical composition of the essential oil from Tarchonanthus camphoratus (L.), leaves against Sitophilus zeamais Motschulsky, and Sitophilus oryzae (L.). African Journal of Agricultural Research, 10(19): 2032-2037 62. Nkeh-Chungag BN, Oyedeji OO, Oyedeji AO, Ndebia EJ (2015) Anti-Inflammatory and Membrane-Stabilizing Properties of Two Semisynthetic Derivatives of Oleanolic Acid. Inflammation, 38(1):61-69. http://link.springer.com/article/10.1007/s10753-014-0007-y 63. Avoseh ON, Oyedeji OO, Aremu K, Nkeh-Chungag BN, Songca SP, Oluwafemi SO, Oyedeji AO (2015) Chemical composition and anti-inflammatory activities of the essential oils from Acacia mearnsii de Wild. Natural Product Research, 29(12): 1184-1188. DOI: 10.1080/14786419.2014.983504. http://www.tandfonline.com/loi/gnpl20 64. Oyemitan IA, Olayera OA, Alabi A, Abass LA, Elusiyan CA, Oyedeji AO, Akanmu MA (2015) Psychoneuropharmacological activities and chemical composition of essential oil of fresh fruits of Piper guineense (Piperaceae) in mice. Journal of Ethnopharmacology, 166: 240–249. 65. Lawal OA, Ogunwande IA, Kasali AA, Opoku AR, Oyedeji AO (2015). Chemical Composition, Antibacterial and Cytotoxic Activities of Essential Oil from the Leaves of Helichrysum odoratissimum grown in South Africa, Journal of Essential Oil Bearing Plants, 18:1, 236-241, DOI: 10.1080/0972060X.2014.901618 66. Avoseh O, Oyedeji O, Rungqu P, Nkeh-Chungag B, Oyedeji A (2015) Cymbopogon Species; Ethnopharmacology, Phytochemistry and the Pharmacological Importance, Molecules 2015, 20, 7438-7453; doi:10.3390/molecules20057438. http://www.mdpi.com/1420-3049/20/5/7438 67. Ndukwe GI, Ojinnaka CM, Oyedeji AO, Nxasana N and Apalata T (2015) Antibacterial Activity of the Fruit of Napoleonaea imperialis P. BEAUV Journal of Innovation and Research in Health Sciences & Biotechnology: Open Access Volume 1 (1): 1-11, http://jiresh-biotech.edmgr.com 68. Dyayiya N, Matewu R, Oyemitan IA, Oyedeji OO, Oluwafemi SO, Songca SP, Nkeh-Chungag BN and Oyedeji AO (2016) Chemical Analysis and Biological Potential of Valerian Root as Used by Herbal Practitioners in the Eastern Cape Province, South Africa. Afr J Tradit Complement Altern Med. 13(1): 114-122. http://dx.doi.org/10.4314/ajtcam.v13i1.16 69. Lawal AO, Ogunwande IA, Opoku AR and Oyedeji AO (2016) Chemical composition and antibacterial activity of essential oils from the rhizomes of Cyperus papyrus L. grown in South Africa. Boletín Latinoamericano y del Caribe de Plantas Medicinales y Aromáticas 15 (3): 137 – 144 70. Taylor A, Oyedeji OO, Aremu O, Oyemitan I, Gwebu ET, Oyedeji AO, Nkeh-Chungag BN (2016). Assessment of the analgesic, anti-inflammatory and sedative effects of the dichloromethanol extract of Schinus molle. European Review for Medical and Pharmacological Sciences, 20: 372-380. http://www.europeanreview.org/article/10232 71. Rungqu P, Oyedeji OO, Avoseh ON, Aremu SO, Nkeh-Chungag BN, Songca SP, Oluwafemi SO, Oyedeji AO (2016). Anti-inflammatory activity of the essential oils of Cymbopogon validus (Stapf) Stapf ex Burtt Davy from Eastern Cape, South Africa. Asian Pacific Journal of Tropical Medicine, 2016: 1-6. http://dx.doi.org/10.1016/j.apjtm.2016.03.031 72. Stolom S, Matewu R, Oyetmitan IA, Oyedeji OO, Oluwafemi SO, Songca SP, Nkeh-Chungag BN and Oyedeji AO (2016) Chemical and Biological Studies of Lobelia (Lobelia inflata Campanulaceae): A Plant Used by Traditional Healers in the Eastern Cape (South Africa), Tropical Journal of Pharmaceutical Research August 2016; 15 (8): 1715-1721. http://dx.doi.org/10.4314/tjpr.v15i8.17 73. Rali S, Oyedeji OO, Aremu OO, Oyedeji AO and Nkeh-Chungag BN (2016) Semisynthesis of Derivatives of Oleanolic Acid from Syzygium aromaticum and Their Antinociceptive and Anti-Inflammatory Properties. Mediators of Inflammation, 2016, Article ID 8401843, 9 pages, 2016. doi:10.1155/2016/8401843. http://dx.doi.org/10.1155/2016/8401843 74. Miya GM Oyemitan IA, Oyedeji OO, Oluwafemi SO, Nkeh-Chungag BN, Songca P, Oyedeji AO (2016) Phytochemical screening, anti-inflammatory and analgesic properties of Pentanisia prunelloides from the Eastern Cape Province, South Africa. Afr J Tradit Complement Altern Med. 13(6):179-185. 10.21010/ajtcam. v13i6.26. http://www.ajol.info/index.php/ajtcam/article/view/145910 75. Tembeni B, Oyedeji OO, Ejidike IP, Oyedeji AO (2016) Evaluation of Trace Metal Profile in Cymbopogon validus and Hyparrhenia hirta Used as Traditional Herbs from Environmentally Diverse Region of Komga, South Africa. Journal of Analytical Methods in Chemistry, 2016, Article ID 9293165, 8 pages, http://dx.doi.org/10.1155/2016/9293165. 76. Lawal OA, Ogunwande I A, Owolabi MS, Opoku AR, Oyedeji AO (2016) Chemical Composition, Antibacterial Activity, and Brine Shrimp Lethality Test of Essential Oil from the Leaves of Eugenia natalitia. Chemistry of Natural Compounds, 52 (4), pp 731–733. 77. Ezekiel CN, Adetunji CO, Owolabi OA, Anokwuru CP, Amos-Tautua BMW, Oyedele OA, Oni OE, Imafidon TF, Onumaegbu CO, Odumosu BT, Oyedeji AO (2016) Volatile Oils of Piper guineense Inhibit Growth and Aflatoxin Production in Aspergillus flavans and A. parvisclerotigenus. Mycotoxicology. 2016:15-23. 78. Ndukwe GI, Ojinnaka CM, Oyedeji AO (2016) Novel Bioactive Triterpenoid Saponin from the Fruit of Napoleonaea imperialis P. BEAUV (Lecythidaceae). International Journal of Chemical Studies, 4(5): 80-87. 79. Lawal AO, Ogunwande IA, Opoku AR, & Oyedeji AO (2016) Zierone: A Sesquiterpene Ketone from the Essential Oil of Cyperus distans L. (Cyperaceae). Advances in Research, 6(6):1-6 80. Chiguvare H, Oyedeji OO, Matewu R, Aremu O, Oyemitan IA, Oyedeji AO, Nkeh-Chungag BN, Songca SP, Mohan S and Oluwafemi OS (2016). Synthesis of Silver Nanoparticles Using Buchu Plant Extracts and Their Analgesic Properties. Molecules, 21(6), 774; doi:10.3390/molecules21060774. http://www.mdpi.com/1420-3049/21/6/774 81. Oyemitan IA, Ojo E and Oyedeji AO (2016) Neuropharmacological profile of ethanolic dried seed extract of Persea americana in mice. African Journal of Pharmacy and Pharmacology, 10(22), pp. 480-492. 82. Lawal AO, Ogunwande IA, Mzimela HMM, Opoku AR, Oyedeji AO (2016) Senecio pterophorus DC. Essential Oils: Antibacterial, Antioxidant, Cytotoxic and Larvicidal Activities. British Journal of Pharmaceutical Research, 12(1):1-9 83. Avoseh ON, Oyedeji OO, Aremu O, Nkeh-Chungag BN, Songca SP, Oluwafemi SO, Oyedeji, AO (2017) Biosynthesis of Silver nanoparticles from Acacia mearnsii De wild stem bark and its antioiceptive properties. Green Chemistry Letters and Reviews, 10(2) 59-68. DOI:10.1080/17518253.2017.1287310 84. Lawal AO, Ogunwande IA, Osunsanmi FO, Opoku AR, Oyedeji AO (2017) Croton gratissimus Leaf Essential Oil Composition, Antibacterial, Antiplatelet Aggregation, and Cytotoxic Activities. Journal of Herbs, Spices & Medicinal Plants, 23:1, 77-87, DOI: 10.1080/10496475.2016.1270245 85. Nyalambisa M, Oyemitan IA, Matewu R, Oyedeji OO, O.S. Oluwafemi SO, Songca SP, Nkeh-Chungag BN, Oyedeji AO (2017) Volatile constituents and biological activities of the leaf and root of Echinacea species from South Africa. Saudi Pharmaceutical Journal (2017) 25 (3), 381-386, http://dx.doi.org/10.1016/j.jsps.2016.09.010 86. Oyemitan IA, Elusiyan CA, Onifade AO, Akanmu MA, Oyedeji AO, McDonald AG (2017) Neuropharmacological profile and chemical analysis of fresh rhizome essential oil of Curcuma longa (turmeric) cultivated in Southwest Nigeria. Toxicology Reports, 4, 391–398. DOI: 10.1016/j.toxrep.2017.07.001 87. Vuyolwethu K, Ojemaye MO, Oyedeji AO, Lewu FB, Oyedeji OO (2018) Assessment of the heavy metal content of wild and cultivated Pelargonium inquinans: An herbal plant used for the treatment of Diverse ailments in South Africa. Fresenius Environmental Bulletin, 27(6), 3914-3919. doi: 10.1155/2016/9293165 88. Tata CM, Gwebu ET, Aremu OO, Nkeh-Chungag BN, Oyedeji AO, Oyedeji OO, Sewani-Rusike CR (2018) Acute toxicity study and prevention of Nω-nitro-L-arginine methyl ester-induced hypertension by Osteopermum imbricatum. Tropical Journal of Pharmaceutical of Research, 17(6), 1111-1118. http://dx.doi.org/10.4314/tjpr.v17i6.18 89. Tata CM, Gwebu ET, Aremu OO, Sewani-Rusike CR, Oyedeji AO, Oyedeji OO, Nkeh-Chungag BN (2018) Acute toxicity and antihypertensive effects of Artemisia afra and Leonotis leonurus in spontaneously hypertensive rats. Research Journal of Biotechnology, 13(1), 20-25. 90. Tanga M, Lewu FB, Oyedeji AO,
Miliaria in Neonates at a South-West Nigerian, State Hospital
No full textMiliaria is also known as heat rashes. It is a disorder of sweat glands that affects all age groups, especially the neonates also, they commonly occur in the tropics. Miliaria has however been understudied globally. We therefore studied neonates over a 3 month peroid at the welfare clinic of the State Hospital, Osogbo, in order to determine the prevalence and the factors associated with heat rashes among neonates. Relevant information was obtained about the babies from their mothers, after which the babies were examined to detect miliaria and possible related factors such as secondary infections and clothing. A total 193 babies made up of 103 boys and 90 girls were studied. Their age range was between 1 and 28 days and 118(61.1%) of them had miliaria. Heat rashes were found on the forehead, face, trunk, neck and limbs in 98(59.8%), 24(14.6%), 19(11.6%), 18(11.0%), and 5(3.0%) babies respectively. Sixty nine babies were over clothed and 124 were not. Forty nine (71.0%) of the 69 over clothed babies had miliaria compared with the corresponding 69(55.6%) of the 124 non-over clothed. ÷2= 4.41, P= 0.04. Also, of the non-over clothed babies, 48 were dressed in cotton while the remaining 76 were either dressed in, polyester, wool or silk fabric. Miliaria was present in 10 (20.8%) of the 48 babies dressed in cotton compared, with the corresponding 59(77.6%) of the remaining 76 babies. ÷2= 37.88, P= 0.00. Of the 118 mothers of the babies with heat rash, 41 (34.7%) correctly recognized their babies condition, but none managed their babies correctly irrespective of their educational status. To reduce the burden of neonatal miliaria, mothers of newborn need to be properly educated concerning the recognition of the condition and avoidance of inappropriate clothing
Human Immunodeficiency Virus Infected Children and Attendant Social Issues Seen At a Nigerian Paediatric Anti-Retroviral Clinic
No full textBackground: HIV infected individuals have other challenging social issues apart from stigmatization. There is a need to fill the gap in knowledge on other attendant social issues associated with paediatric HIV disease and how they impact on care.
Aim: To document the social issues identified among children attending the paediatric anti-retroviral clinic of Nigerian tertiary hospital, with a view to discovering how this affects the care of the patients.
Methodology: Consecutive consenting HIV infected children and their care givers attending Ladoke Akitola University of Technology Teaching Hospital, Osogbo, South West Nigeria, were studied. Information on their socio-demographic details and perceived social challenges and how they affect care was obtained. Data obtained was analysed using SPSS version 16.
Results: Of the 55 children studied 43(78.2%) had social issues. Some children had more than 1 social issue. The ages of the children studied ranged from 3 months to 13years, with a mean of 5.7 ± 3.2 and the 55 consisted of 28 boys and 27 girls giving a male to female ratio of 1.0: 1.0. The range and mean of the ages of the fathers was 20 – 71years and 43.2 ± 10.3years respectively, while it was 20 – 54 years and 34.7 ± 5.8 years respectively for the mothers. The social issues identified were non-disclosure of HIV status to the HIV infected children, fear of stigmatization of children and accompanying caregiver or parents, sero-discordant HIV status of the parents, death of one or both parents (single or double Orphans), single parent, divorced or separated parents, parental polygamy. Other social issues are low socioeconomic status, poor parental education, neglect of the HIV infected child and residence in remote rural settings. All of the social issues listed impacted negatively in one way or the other on the care of the HIV infected children.
Conclusion: Social issues are common among HIV infected children. Effective strategies to mitigate against the effect of these social issues need to be identified and instituted in order to improve on care
A gendered study of young adult contraceptive use at one university in KwaZulu-N atal
No full textThis study explores contraceptive use among young adult male and female students (aged 18-25) who visit the campus clinic at a university in KwaZulu-Natal. Both a descriptive survey and face to face interviews were used for data collection.
In this study, it is affirmed that gender stratification, societal attitudes, and misconceptions about contraceptive use play an important role in the attitudes of young adults, male and female towards contraception and its use. Evidence of this is the high use of condoms amongst both male and female students’ compared with other available methods. Among female students this was highly attributed to personal convenience and comfort with condom use as an unmarried young woman. It was clear from the data collected that respondents themselves attached some stigma to being associated with the use of contraceptive pills or having to visit the clinic regularly for injections as young unmarried women. Male respondents affirmed the use of the condom, although this was hardly with the view of taking reproductive/contraceptive responsibility, but rather, it was attributed to the function of the condom as a safe sex method that offered protection against sexually transmitted diseases and infections. Also evident from the study was the fact that male respondents felt more comfortable with their sexual functioning than the female respondents. This was easily attributed to the role of societal gender stratification in an individual’s life
A Review of Neonatal Admissions in Osogbo, Southwestern Nigeria.
No full textA retrospective analysis of the records of all neonatal admissions into the Special Baby care unit (SCBU) of LAUTECH Teaching Hospital, Osogbo between January 2006 and December 2007 was undertaken. There were 605 admissions (371 males and 234 females) with 308 (50.9%) being admitted in 2006 and 297 (49.1%) in 2007. Admission weights ranged between 0.65kg and 5.20kg with the mean weight of 2.72 ± 0.76kg. There were 317 (52.5%) inborns and 288 (47.5%) outborns. Primary indications for admission were low birth weight in 228 (47.7%), birth asphyxia in 197 (32.5%), neonatal septicaemia -154 (25.4%), neonatal jaundice 72 (11.9%) and respiratory distress in 56 (9.2%). One hundred and ten (18.2%) of the 605 babies died. Of the 110 babies who died, 80 (72.7%) were outborn while 30 (27.3%) were inborn. The pattern of the causes of death mirrors that of admissions. The main causes of admissions and deaths are preventable. The mortality of 18.2% is unacceptably high. Sick babies who had been delivered outside the teaching hospitals stood a triple chance of dying compared with those born in the teaching hospitals. To improve and work towards achieving MDG4,a much better commitment of government to maternal and child health is needed.Keywords: Neonatal admissions, morbidity, mortality, Nigeri
Fatal scorpion sting in a child
No full textFatal scorpion stings are rare in Nigeria. Hitherto, there has been no report from Nigeria of death following scorpion stings. This report is that of a 2‑year‑old boy who was stung by a scorpion while playing outside his home environment in Osogbo, South West Nigeria. He subsequently presented to the Children Emergency Unit of Ladoke Akintola University of Technology Teaching Hospital, Osogbo, in pain and with features of shock. He died within 2 h of admission despite all treatment given to relieve pain and manage shock. The case is reported in order to share the important lessons learned.Key words: Fatal, pediatric, scorpion stin
The influence of maternal socioeconomic status on the management of malaria in their children: Implications for the 'roll back malaria' initiative
No full textNo Abstract.Keywords: Child care; malaria; socioeconomic status The Nigerian Journal of Paediatrics Vol. 32 (2) 2005: pp. 40-4
Biological evaluation and semi-synthesis of Isolated compounds from (Syzygium aromaticum (L.) Merr. & Perry) Buds.
No full textNatural products play a fundamental role in modern drug discovery as they continue providing diverse bioactive lead compounds for new drug formulation. However, isolation of these valued compounds is problematic. On the other hand, the morbidity and mortality rates caused by non-communicable diseases are increasing with improved longevity. Thus, the study herein focused on the isolation of plant-derived compounds from Syzygium aromaticum and evaluated their biological properties.
Syzygium aromaticum is a well-known plant which belongs to family Myrtaceae. Dried flower buds of S. aromaticum were subjected to sequential solvent extraction. The ethyl acetate extract (15.535 g) was subjected to column chromatography using a silica gel (0.063-0.200 mm) for isolation. This has led to the isolation of three distinct compounds that were identified as eugenol, maslinic acid (MA) and oleanolic acid (OA). The structural elucidation of these valued compounds was done using NMR, GC-MS, LC-MS, FT-IR and Mp. Further semi-synthesis of the oleanolic acid afforded acetate and ester OA-derived compounds with better solubility properties. All these compounds were evaluated for analgesic and anti-inflammatory properties.
All tested compounds were administered at a dose of 40 mg/kg to both Wistar rats and Swiss mice. Significant (p<0.01) analgesic and anti-inflammatory properties are obtained for all compounds. The effects of eugenol in all experiment were better except in the thermal-induced pain or tail flick test. In the case of modified compounds, the formalin induced pain test disclosed that oleanane derived compounds confessed analgesic and anti-inflammatory effects better than OA, whereas, in tale flick test oleanolic acid proved superior analgesic effects compared to all its derivatives with the exception of the acetyl-derivative. Acute anti-inflammatory test showed that acetyl-derivatives were more active than other compounds.
In conclusion, chromatographic techniques and semi-synthesise of oleanolic acid have resulted to several plant-derived compounds with analgesic and anti-inflammatory properties. The semi-synthesized compounds may serve as alternative drug candidates for new analgesic and anti-inflammatory drug formulatio
