141 research outputs found
Heme polymerization inhibition activity (HPIA) assay of synthesized xanthone derivative as antimalarial compound
No full textGroundwater Vulnerability Mapping: A New Mapping Method as a Useful Decision-Making Tool for Oil and Gas Industry
No full textThe implementation of case study with module-assisted to improve students’ understanding on phytochemistry course
No full textSynthesis and Characterization of 2,3,4-Trihydroxy-5-methyl Xanthone as Antimalarial Compound
No full textSynthesis of xanthone derivatives had been conducted to obtain new antimalaria active compounds. The characterization of the synthesized xanthones was also conducted. Synthesis of xanthone was conducted from the raw material of hydroxybenzoic acid and phenol derivatives using Eaton's reagent via acylation-dehydration reaction by modified Grover, Shah and Shah (GSS) method. The synthesis of 2,3,4-trihydroxy-5-methyl xanthone was carried out using gallic acid, o-cresol and Eaton's reagent.The mixture was heated for 3 h at 80 °C to yield 2,3,4-trihydroxy-5-methyl xanthone in 43% yield as dark red viscous liquid. The results of IR, 1H-NMR and 13C-NMR analysis of sampleshowed that the compound2,3,4-trihydroxy-5-methyl xanthonehas successfully synthesized
Impregnated Bits Design and Optimization: An Iterative Method for Improving Drilling Performances. Case Study: Hassi Messaoud Cambrian Reservoir in Algeria
No full textAbstract
Horizontal wells are drilled in Hassi Messaoud oilfield with 6" drains of +/−800m into the Cambrian reservoir using both PDM and Turbine. The multi layered reservoir is +/-3400m deep, mainly quartzite, sandstone and silt. Looking at the rock strength, the confined compressive strength can reach 60 kpsi. Therefore enhancing ROP and durability, when drilling the very hard and very abrasive Cambrian reservoir in Hassi Messaoud, remains one of the major drilling challenges.
This paper describes the iterative approach by which SONATRACH and NOV Downhole Tools Algeria are developing and improving impregnated bits for the very hard and very abrasive formations; for both applications: PDM and Turbine as well. The main objectives are to:
Enhance ROP. Increase durability. Maintain inclination and reasonable dogleg severity. Be able to drill out float equipments and shoe. Fit for both PDM and Turbine application Suit both OBD and UBD application
As all new bit types, a complete field study was carried out, including logs and rock strength analysis, offset wells comparison in order to bring into the light the first version of the design. Four versions of the impregnated bit were tested, so far.
The first version drilled 120m. A second version was tested, with an improvement related to the anti-coring cutters, replacing them by a new generation more wear resistant. The subsequent improvement consisted in increasing blade volume, enabling one of the best ROP achieved in Hassi Messaoud 5.27 m/h. To improve durability, blade volume was increased more. The bit achieved 365 m in one run, with an average ROP of 3.49 m/h.
In the last version developed and tested, an increase in the grit mix was made. The bit drilled an interval of 399 m with an average ROP of 3.89 m/h.
Furthermore, several design considerations have been taken into consideration in order to improve impregnated bits in relation to different types of lithology drilled. The newest design has the same blade volume and the same grit mix as the last bit design recently used in Hassi Messaoud field. However the blades are thicker and the hydraulics / water ways are optimized.</jats:p
Estrategias metodológicas implementadas por el docente para motivar el proceso de aprendizaje en la disciplina de Ciencias Naturales en estudiantes de 6to grado turno matutino del Colegio Público Filemón Rivera Quintero distrito v de la ciudad de Managua durante el II semestre del año lectivo 2016
No full textEl presente trabajo investigativo se realizó en el Colegio Público Filemón Rivera Quintero del distrito V de la ciudad de Managua con estudiantes de 6to grado turno
matutino en el II semestre del año lectivo 2016.
Esta investigación tiene como propósito analizar las estrategias metodológicas implementadas por el docente para motivar el proceso de aprendizaje en el área
de Ciencias Naturales en los estudiantes de 6to grado.
El enfoque de la investigación es cualitativo ya que se utilizaron recolección de datos sin mención numérica para dar respuestas a las interrogantes de investigación en el proceso de interpretación y análisis. Es de tipo descriptivo porque consiste en llegar a conocer las situaciones, costumbres y actitudes predominantes a través de la descripción exacta de las actividades lo cual nos permitió identificar si las estrategias metodológicas implementadas por el docente motivan el proceso de aprendizaje en la disciplina de Ciencias Naturales en los estudiantes de 6to grado. Para obtener la información que sustenta este trabajo investigativo se utilizaron técnicas para la recolección de datos: la encuesta dirigida a los estudiantes, la entrevista al docente, guía de observación en el aula de clase con el propósito de determinar las estrategias metodológicas implementadas por el docente para motivar el aprendizaje en la disciplina de Ciencias Naturales. La población consta de 72 estudiantes de los cuales 36 fueron los seleccionados de forma aleatoria simple para formar la muestra. El análisis se realizó a través de la técnica de la triangulación de datos los cuales se agruparon de acuerdo a los propósitos ya planteados en la investigación .La triangulación tiene como objetivo comparar la información obtenida en la aplicación de los instrumentos o técnicas con la teoría para dar respuestas a los propósitos planteado
Implementasi Algoritma Topsis pada Decision Support System Pemilihan Perguruan Tinggi Swasta Program Studi Informatika/Teknik Informatika
No full textPDDIKTI noted that the number of new students in Indonesia has continued to increase since the academic year 2016/2017. The increase in the number of new students every year proves that the level of public awareness of the importance of education is increasing. On this basis, the author initiated the design of a system that could be used by prospective new students or students who have completed in Higher Secondary School educators and their equivalents. The system the author designed is a Decision Support System by implementing topsis algorithms on its calculations. The result of this research is a system of decision support for the selection of PTS specialized program of study in Informatics/Technology
Synthesis AndCharacterization of 2,3,4-Trihydroxy-5-methyl Xanthone as Antimalarial Compound
No full textSynthesis of xanthone derivatives had been conducted to obtain new antimalaria active compounds. The characterization of the synthesized xanthones was also conducted.Synthesis of xanthone was conducted from the raw material of hydroxybenzoic acid and phenol derivatives using Eaton's reagent via acylation-dehydration reaction by modified Grover, Shah and Shah (GSS) method. The synthesis of 2,3,4-trihydroxy-5-methyl xanthone was carried out using gallic acid, o-cresol and Eaton's reagent.The mixture was heated for 3 h at 80 °C to yield2,3,4-trihydroxy-5-methyl xanthone in 43% yield as dark red viscous liquid. The results of IR, 1H-NMR and 13C-NMR analysis of sampleshowed that the compound2,3,4-trihydroxy-5-methyl xanthonehas successfully synthesized
Diseño de un centro de educación básica especial, rehabilitación y capacitación aplicando las teorías del FENG SHUI en el distrito de Catacaos 2020
No full textEl presente trabajo de investigación comprende el análisis de la problemática
y el diagnóstico situacional relacionado al servicio de educación básica especial y
su infraestructura actual, con el propósito de diseñar un equipamiento que responda
a las necesidades de los niños con discapacidades severas o multidiscapacidades.
Bajo un enfoque basado en las necesidades del alumno, el proyecto tiene
como objetivo el desarrollo de un nuevo modelo arquitectónico que busca lograr el
equilibrio entre la forma, la función, el espacio y el entorno natural, aplicando
conceptos de una de las filosofías más antiguas, el Feng Shui, también conocido
como “el arte del acomodo”, que surge a partir de las interrogantes sobre la
influencia del paisaje y las formas en conjunto con el ser humano en un entorno
determinado.
La investigación se organiza en diez capítulos, en los cuales se describe el
marco teórico, la metodología, investigación programática, análisis e interpretación
de datos, programa de necesidades y parámetros normativos, obteniendo como
resultado la propuesta de diseño integral del Centro de Educación Básica Especial,
Rehabilitación y Capacitación, contribuyendo de esta manera a la solución de la
problemática.The present research work includes the analysis of the problem and the situational
diagnosis related to the special basic education service and its current infrastructure,
with the purpose of designing an equipment that responds to the needs of children
with severe disabilities or multi-disabilities.
Under an approach based on the student's needs, the project aims to develop a new
architectural model that seeks to achieve a balance between form, function, space
and the natural environment, applying concepts from one of the oldest philosophies. ,
Feng Shui, also known as ““the art of accommodation““, which arises from the
questions about the influence of the landscape and the forms in conjunction with the
human being in a given environment.
The research is organized into ten chapters, in which the theoretical framework,
methodology, programmatic research, data analysis and interpretation, program of
needs and normative parameters are described, resulting in the comprehensive
design proposal of the Center for Special Basic Education, Rehabilitation and
Training, thus contributing to the solution of the problem.Tesi
A Holistic Approach to Drilling Parameters and Drill Bit Design Optimization Improves Rate of Penetration by 37%, Hassi Messaoud OMfield-Algeria
No full textAbstract
Drilling challenges in the Hassi Messaoud (HMD) oilfield have proven to be equal to the magnitude of its production. Historically, wells drilled in this field were vertical, moderate borehole diameters having a long 12 ¼"section. In order to increase production and to gain a better understanding of the reservoir, Sonatrach Drilling engineering moved to moderately deviated large diameter boreholes, delivering 1000 meters of drain in the reservoir.
Instead of the conventional 12 1/4’’ vertical section, 1800 meters was drilled in 16’’ diameter. This section consists of abrasive sands, inter-bedded evaporate/carbonate and sand/claystone formations prone to instability and collapse. In addition, there is a 30 meter band of extremely hard dolomite. Rock strengths vary widely from 5 Kpsi to 30Kpsi.
Since early 2000, Sonatrach and National Oilwell Varco (NOV) have been working as a team to rise to the challenges presented by the larger hole size. Most significantly drilling vibrations, slow penetration rates, increased trips to TD, severe bit and BHA damage and NPT due to stuck pipe while pulling out-of-hole.
This article describes first, the process by which significant performance improvement was achieved as a result of combining innovative bit design techniques and technologies, BHA optimization, optimization of parameters through BHA dynamics modelling, and formation Rock Strength Analysis.
Secondly, the article discusses optimized techniques introduced to enhance performance for the 16’’ section on rigs that have been recently equipped with VFD - AC top drives and properly deal with torque limitation issues.
This enabled Sonatrach to repeatedly set ROP drilling records as well as consistently making section TD in a single run. The net result was a 37% improvement in rate of penetration1.</jats:p
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