1,070 research outputs found
The amazing Dr Kouznetsov
No full textThe author explores the career of creationist Dimitri Kouznetsov as an author in the field of archaeology. He highlights the articles written by Kouznetsov on conservation, creationism and textiles. Kouznetsov career in the field of archeology was marked by an article he published in the 'Journal of Archaeological Science.' Since then, he continued to publish different articles relevant to field of archaeology. The author notes that Kouznetsov has contributed much to archaeological literature.published_or_final_versio
YURI KOUZNETSOV AND POLAND
No full textThis article analyses a translation of one of Adam Mickiewicz’s Sonnets from the Crimea made by Yuri Kouznetsov, a famous Russian poet. It is not incidental that some Polish toponyms coincide with personal names mentioned in Kouznetsov’s poetry. The author of the article examines the system of symbols that Kouznetsov resorts to in his texts concerning either Polish themes or stories. It is concluded that in one of his philosophical verses Kouznetsov proclaimed Polish and German culture to have messianic value
Synthesis of some secondary amine derivatives bearing a heteroaryl fragment
No full textKouznetsov, V.V. (reprint author) y Astudillo L. Instituto de Química de Recursos Naturales, Universidad de Talca, Casilla: 747, Talca, Chile.Diverse N-(heteroarylmethyl)anilines were easily prepared from corresponding aldimines derived from commercially available aromatic aldehydes and anilines. New series of substituted NH-tetrahydroquinolines were also prepared using imino-Diels-Alder reaction between aldimines and N-vinylpyrrolidin-2-one in the presence of (BF3OEt2)-O-. and the multi-component condensation reactions using a friendly ecological catalyst(BiCl3). The secondary amines obtained bearing a heteroaryl moiety were tested as possible antibacterial and antifungal agents
An efficient synthesis of hexahydro oxaisoindolo[2,1-a]quinoline derivatives via the Diels-Alder reactions
No full textKouznetsov, V.V. (reprint author), Univ Talca, Inst Quim Recursos Nat, Lab Sintesis Organ, Casilla 747, Talca, Chile.he straight forward synthesis of new carboxylic acids with hexahydro-oxaisoindolo[2.1-a]quinoline core from the 2,4-disustituted 1,2,3,4-tetrallydroquinolines bearing a furan fragment via the intramolecular Diels-Alder reaction has been proposed. It was demonstrated that synthesis of key precursors can be realized with excellent level of diastereoselectivity either by imino-Diels-Alder reaction or multi-component condensation approach
Effective construction of new molecules quinolines and benzofurans via cycloaddition reactions [4+2] and [3+2] from renewable raw materials
No full textLos compuestos heterocíclicos siempre han demostrado promisorias propiedades como biomoléculas. Dentro de la mayoría de metodologías sintéticas utilizadas para la construcción de sistemas heterocíclicos sobresalen las reacciones de cicloadición [4+2] y [3+2], poderosas herramientas sintéticas gracias a su gran versatilidad y elevada estereoselectividad. Teniendo en mente la necesidad de combatir las enfermedades que aquejan a la humanidad, ha habido un progreso significativo en el desarrollo de estrategias para sintetizar nuevos agentes terapéuticos. Continuando con la investigación del Laboratorio de Química Orgánica y Biomolécular dirigida al desarrollo nuevos compuestos que sean modelos atractivos en la búsqueda de sustancias bioactivas y la implemententación de nuevas metodologías acordes a la química sostenible, en el desarrollo de esta investigación se veló por reducir el impacto ambiental de los procesos de síntesis y purifi por ejemplo, estrategias de síntesis que disminuyeron el número de pasos sintéticos de acuerdo con la economía atómica (condensación multicomponente); en lo posible se utilizó condiciones catalíticas; se intentó siempre maximizar la eficiencia energética ejecutando las reacciones a temperatura y presión ambiente; también se implementó el uso de medios y condiciones de reacción seguras (CO2 en condiciones supercríticas y medios de reacción como el PEG-400) y gracias a la diversidad de la flora colombiana, en este trabajo se contó con precursores considerados materias primas renovables, como el trans-anetol e isoeugenol, productos naturales fenólicos (extraídos de los aceites esenciales o extractos de fuentes vegetales). En resumen, esta investigación doctoral se orientó nuevos compuestos tetrahidroquinolínicos y dihidrobenzo[b]furanos) de sencillez estructural con alto potencial farmacológico usando metodologías acordes con la química sostenible, buscando hacer un modesto aporte al desarrollo de la química medicina colombiana en la etapa de descubrimiento de nuevas entidades farmacológicas con actividad biológica potencial.DoctoradoDoctor en QuímicaTetrahydroquinolines, indeno[2,1-c]quinoline; 2,3-Dihydrobenzofurans; Antiprotozoan activity; Antitumor activity; Antifungal activity. DESCRIPTION: Heterocyclic compounds always have shown promising properties as biomolecules. Inside of synthetic methodologies currently used for the construction of heterocyclic systems stand out the cycloaddition reactions [4+2] and [3+2], powerful synthetic tools because have shown a high versatility and stereoselectivity. Bearing in mind the need to combat the diseases that afflict humanity a significant progress has existed in the development of strategies for synthesizing new therapeutic agents. Continuing with the research of the Laboratory of Organic and Biomolecular Chemistry toward of development of new compounds that are attractive models in the search for bioactive substances and in the search and development of this research was searched to reduce the environmental impact of the synthesis and purification processes consistent with the principles of "green chemistry". Were used for example, synthesis strategies that reduced the number of synthetic steps according to the atomic economy (multicomponent condensation); catalytic conditions; was attempted always to maximize energy efficiency by running the different reactions to room temperature and pressure; was implemented of use of media and reaction conditions more safe (CO2 in supercritical conditions and reaction media such as PEG-400) and finally due to of the Colombia diversity, in this study were used as precursors renewable raw materials, such as trans-anethole and isoeugenol, natural phenolic products (extracted from of essential oils or seed from plant sources). In short, this doctoral research work was oriented in find "molecular models", substances with structural simplicity and important potential pharmacological using methodologies consistent with sustainable chemistry, trying to make a modest contribution to the development of Colombian medical chemistry in the discovery stage of new pharmaceutical products with potential biological activity. Doctoral Thesis. § Facultad de Ciencias, Escuela de Química, Research advisors: KOUZNETSOV, Vladimi
Social network analysis for startups: finding connections on the social web
No full textDoes your startup rely on social network analysis? This concise guide provides a statistical framework to help you identify social processes hidden among the tons of data now available. Social network analysis (SNA) is a discipline that predates Facebook and Twitter by 30 years. Through expert SNA researchers, you''ll learn concepts and techniques for recognizing patterns in social media, political groups, companies, cultural trends, and interpersonal networks. You''ll also learn how to use Python and other open source tools-such as NetworkX, NumPy, and Matplotlib-to gather, analyze, and vi
The strange quark polarization from COMPASS data
No full textThe strange quark helicity distribution was derived at LO from the inclusive asymmetry and the semi-inclusive asymmetries , , , measured by COMPASS in polarised deep inelastic muon-deuteron scattering. The distribution of is compatible with zero in the whole measured range. The value of the rst moment of and its error are very sensitive to the assumed value of the ratio of the -quark to -quark fragmentation functions into positive kaons
The spin physics results from COMPASS
No full textCOMPASS (COmmon Muon and Proton Apparatus for Structure and Spectroscopy) is a fixed target experiment at CERN dedicated to studies of the spin structure of the nucleon and of the spectroscopy of hadrons. During the years 2002-2004, 2006-2007 and 2010-2011 the COMPASS collaboration has collected a large amount of data by scattering polarized 160(200) GeV/c muons on polarized 6LiD and NH3 targets. The COMPASS results on quark and gluon helicities are discussed, as well as results on transverse spin and transverse momentum effects in semi-inclusive deeply inelastic scattering
COMPASS experiment at CERN: hadron spectroscopy and open charm results
No full textAbstractCOmmon Muon and Proton Apparatus for Structure and Spectroscopy (COMPASS) is a fixed target experiment at CERN dedicated to studies of the spin structure of the nucleon and of the spectroscopy of hadrons. During the years 2002–2004 and 2006–2007, the COMPASS collaboration has collected a large amount of data by scattering polarized 160 GeV/c muons on polarized 6LiD and NH3 targets. These data were used to evaluate the gluon contribution to the nucleon spin. The gluon polarization Δgg was directly measured from the cross-section helicity asymmetry of D0 mesons production in the photon-gluon fusion reaction.During 2008 and 2009, the world leading data sets were collected with hadron beams which are currently being analyzed using Partial Wave Analysis (PWA) technique. COMPASS is performing a search for JPC-exotic mesons, glueballs and hybrids, through light hadron spectroscopy in high energy 190 GeV/c hadron-proton reactions using both centrally produced and diffractive events. Preliminary results from these searches are discussed
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