3,140 research outputs found

    Rozpor ako východisko, láska ako smer u Simone Weilovej (Contradiction as base, Love as direction in writings of Simone Weil)

    No full text
    Article is explaining contradiction and love, Simone Weil‘s essential terms of hermeneutics of human Being. It introduces close relation of these terms with her understanding of God as well as with her overall concept of religion. Author also mentions Simone Weil‘s inspirations with philosophical and spiritual concepts of the East

    Array-Based Comparative Genomic Hybridization in Early-Stage Mycosis Fungoides: Recurrent Deletion of Tumor Suppressor Genes BCL7A, SMAC/DIABLO, and RHOF

    No full text
    The definitive version may be found at www.wiley.comAbstractThe etiology of mycosis fungoides (MF), the most frequent form of cutaneous T cell lymphoma (CTCL), is poorly understood. No specific genetic aberration has been detected, especially in early‐stage disease, possibly due to the clinical and histological heterogeneity of patient series and to the different sources of malignant cells (skin, blood, or lymph node) included in most studies. Frozen skin biopsies from 16 patients with early‐stage MF were studied using array‐based comparative genomic hybridization. A DNA pool from healthy donors was used as the reference. Results demonstrated recurrent loss of 19, 7p22.1‐p22.3, 7q11.1‐q11.23, 9q34.12, 12q24.31, and 16q22.3‐q23.1, and gain of 8q22.3‐q23.1 and 21q22.12. The 12q24.31 region was recurrently deleted in 7/16 patients. Real‐time PCR investigation for deletion of genes BCL7A, SMAC/DIABLO, and RHOF—three tumor suppressor genes with a putative role in hematological malignancies—demonstrated that they were deleted in 9, 10, and 13 cases, respectively. The identified genomic alterations and individual genes could yield important insights into the early steps of MF pathogenesis. © 2008 Wiley‐Liss, Inc.Angelo Carbone, Laura Bernardini, Francesco Valenzano, Irene Bottillo, Clara De Simone, Rodolfo Capizzi, Anna Capalbo, Francesca Romano, Antonio Novelli, Bruno Dallapiccola and Pierluigi Ameri

    “I beg you to tell me what has become of Djamila”: The Political Mobilization of Simone de Beauvoir’s Readers During the Boupacha Affair

    No full text
    By Sophia Millman This is a condensed version of a Masters thesis dedicated to the political mobilization of Simone de Beauvoir’s readers. The citations from the letters were translated from French by the author. *** On June 2, 1960, the French government ordered all copies of the daily Algiers edition of Le Monde seized and destroyed to suppress the publication of Simone de Beauvoir’s article “Pour Djamila Boupacha.” Beauvoir, a self-professed “woman of letters”, not “of action[1]”, and one ..

    A comparative study of form and theology in the works of Flannery O'Connor and Simone Weil

    No full text
    In this comparative study of the form and theology of Flannery O'Connor and Simone Weil I interrogate how Weil's philosophical writings and her theology illuminate O'Connor's use of both narrative and non-fictional forms, and her Catholicism. The Introduction analyses how Weil's concept of superposed reading provides a new method of approaching both O'Connor, her writings, and O'Connor studies, and focuses on how such apparently different women interconnect. Chapter One explores how both Weil and O'Connor attempt to write their theologies on the souls of their readers yet are each subject to constraints imposed by form. Weil's concept of locating equilibrium between incommensurates is discussed, and her distinctively philosophical approach to fictions and fictionality is used to investigate O'Connor's notion of prophetic fictions and the writer's role. Chapter Two assesses how both writers revivify Christian paradoxes. Weil's monstrous concept of affiiction, and O'Connor's use of the grotesque genre to jolt secular man into an awareness of the sacred are scrutinised. Chapter Three studies how both writers consider an encounter between God and man is possible through the action of grace. My Conclusion interrogates how Weil's work can deepen our understanding of O'Connor's writings, and examines how successful O'Connor is at realising a truly Christian literature. I conclude that despite being a writer of powerful fictions, O'Connor can not be totally successful in her mission as writer-prophet because ultimately fiction escapes orthodoxy

    Microlinices benthovus Simone 2014

    No full text
    benthovus, Microlinices Simone, 2014 Microlinices benthovus Simone, 2014: 575–578 (figs 6A–J, 7A–H, 11A–C). Gastropoda, Naticidae Paratypes (22 spc): MZSP 105269. Paratypes 1 (15 spc): MZSP 105270. Paratypes 2 (16 spc): MZSP 105271. Paratypes 3 (7 spc): MZSP 105272. Localities: Brazil, Espírito Santo, off Itaúnas, Abrolhos Slope, 18°59' S, 37°50' W, MD55 sta. DC 73, 637 m depth, 27 May 1987; 1) 19°00' S, 37°48' W, MD55 sta. DC72, 950– 1050 m, 27 May 1987; 2) off Regência, 19°40' S, 37°48' W, MD55 sta. CB77, 790– 940 m depth, 27 May 1987; 3) off Itaúnas, Abrolhos Slope, 19°01' S, 37°47' W, MD55 sta. CB79, 1500–1575 m depth, 28 May 1987. Collectors: P. Bouchet, J.H. Leal and B. Métivier. Preservation: Dry. Remarks: Former MNHN, Paris. The catalogue number MZSP 105250 is mentioned twice in Simone’s (2014) paper, among the paratypes of M. ibitingus Simone, 2014 and M. benthovus. This duplicity was a mistake by the author: the latter is an erroneous designation and should be disregarded. The only valid paratype lots for M. benthovus are the ones shown above.Published as part of Cavallari, Daniel C., Dornellas, Ana Paula S. & Simone, Luiz Ricardo L., 2016, Second annotated list of type specimens of molluscs deposited in the Museu de Zoologia da Universidade de São Paulo, Brazil, pp. 1-59 in European Journal of Taxonomy 213 on page 10, DOI: 10.5852/ejt.2016.213, http://zenodo.org/record/384012

    Modifications of sinusoids area in the progression of liver disease

    No full text
    The finf endpoint of this study is to find new markers m document the progression of the disease through a quantitative hictamorphometric data on the went and not be assessed. The semnd endpoint will be to etart building a mathematical database to help m achieve a score in the future. In the images studied it was found a difference in size of areas between the three graups of patients considered. In particular, we made a comparisan betwm the areas of the sinusoids of noimal subjects and cirrhotic patients with areas that were considered to have a different degme of steatosi

    Was bringt die Föderalismusreform? Wahrscheinliche Effekte der geänderten Zustimmungspflicht

    No full text
    The recently enacted reform of German federalism is supposed to make legislation faster, more efficient and better. To what extent are these expectations justified? In order to assess the likely effects of the reform, this study uses a research design that was recently applied by the Research and Reference Services of the German Bundestag (parliament): we estimate the future effects of the reform by analyzing the impact it would have had on the legislation in the 14th and 15th term of the Bundestag if it had already been been in force at that time. In particular we ask: To what extent would the number of laws requiring the consent of the states' chamber, the Bundesrat, have been reduced? Which type of laws would have been affected by this reduction - the more controversial ones, or the less controversial ones? Which policy sectors would have seen the greatest reduction? How much would the reduction have increased the government's capacity to act effectively? Would the legislative process have been accelerated? -- Die verabschiedete Föderalismusreform soll die Gesetzgebung in Deutschland schneller, effizienter und besser machen. Inwiefern sind diese Erwartungen berechtigt? Zur Abschätzung der Reformfolgen auf die Bundesgesetzgebung folgen wir in dem vorliegenden Working Paper einer Vorgehensweise, die der Wissenschaftliche Dienst des Bundestages kürzlich in einer Studie angewandt hat: Die Auswirkungen der Föderalismusreform insbesondere auf die Zustimmungspflicht werden anhand der Gesetzgebung der 14. und 15. Legislaturperiode untersucht. Wir fragen insbesondere: Wie stark hätte sich der Anteil der Zustimmungsgesetze verringert, wenn die neuen Zustimmungsregeln schon in diesen beiden Legislaturperioden gegolten hätten? Wären eher zwischen Regierung strittige oder unstrittige Gesetze von der Zustimmungspflicht befreit worden? Welche Politikbereiche wären betroffen? Wie sehr hätte sich die politische Handlungsfreiheit der Bundesregierung erhöht? Wäre die Gesetzgebung durch die veränderten Zustimmungsregeln beschleunigt worden?

    L'incontro fra Enrico Novelli e Pirandello. Con le illustrazioni e il testo a firma di Yambo. "La Nazione" 9 marzo 1926

    No full text
    Il contributo pubblica una intervista assai rara uscita su "La Nazione" il 9 marzo 1926: in essa, firmata dal noto scrittore e disegnatore E. Novelli, si rivela il senso della parabola Così è (se vi pare), alla quale Pirandello si riferisce (e così Novelli nelle illustrazioni), anziché parlare della commedia che sta rappresentando in quel momento al teatro Politeama di Firenze, dove si svolge l'incontro. Questa intervista conferma l'interpretazione data dalla sottoscritta nell'introduzione a Così è (se vi pare), Mondadori 2021

    Bridging the gap between human beings and digital twins in radiology

    No full text
    Radiology is a multimodal discipline that makes extensive use of different imaging methods, producing a huge amount of quantitative, longitudinal, and digital data over time. Radiologists must, therefore, be at the center of the “technological revolution” of healthcare. Modern computational models are boosting the capability to diagnose and prognosticate disease, which will drive individualized treatment plans. This might be achieved by accurately modeling an individual’s progression along a treatment pathway or algorithm—from pretreatment patient selection to customizing treatment nuances and through reevaluation and follow-up [1]. However, presently, the current applications of artificial intelligence (AI) in medicine can only address narrowly defined tasks; this is in contrast to the human ability to think clinically, analyzing and synthesizing data from multiple sources and modalities [2]. In this landscape, the technology that will likely support clinicians in disease prognosis and prediction of response to therapy in the near future are Digital Twin (DT) technologies, also referred to as Virtual Human Twins in Europe
    corecore