1,721,021 research outputs found
Limit of detection comparison for surface wave biosensors
No full textBloch surface waves (BSW) propagating at the surface of truncated, one-dimensional crystals are valid candidates to improve sensors based on surface plasmon polaritons, usually referred to as surface plasmon resonance (SPR). The low losses introduced by the dielectric BSW stacks enable to achieve resonance widths much below the ones of SPR, thus proposing improved sensing results. A simplified, bi-linear model of the resonance intensity distribution is applied to estimate the effect of the resonance properties onto the measurement noise. This yields a limit of detection (LoD) that is used to optimize a BSW supporting thin film stack and to quantitatively compare SPR and BSW sensors. The results indicate that an order of magnitude reduction of the LoD is within reach when sufficient sampling of narrow BSW resonances is achieved. © 2014 SPIE
Design rules for combined label-free and fluorescence Bloch surface wave biosensors
Full text linkWe report on the fabrication and physical characterization of optical biosensors implementing simultaneous label-free and fluorescence detection and taking advantage of the excitation of Bloch surface waves at a photonic crystal’s truncation interface. Two types of purposely-designed one dimensional photonic crystals on molded organic substrates with micro-optics were fabricated. These feature either high or low finesse of the Bloch surface wave resonances and were tested on the same optical readout system. The experimental results show that designing biochips with a large resonance quality factor does not necessarily lead in the real case to an improvement of the biosensor performance. Conditions for optimal biochips’ design and operation of the complete bio-sensing platform are established
Direct comparison of the performance of Bloch surface wave and surface plasmon polariton sensors
No full textWe report on the direct experimental comparison of the sensitivity and figure of merit of biosensors based either on surface plasmon polaritons on metal layers or on Bloch surface waves on one dimensional photonic crystals. The comparison was carried out by making use of a commercial surface plasmon resonance platform that was slightly adapted for these experiments. Although the experimental conditions are not optimized for Bloch surface waves, our experiments demonstrate that both types of biosensors show a similar figure of merit for biochips deposited on low cost molded plastic substrates. For glass substrates with better optical quality, the increased homogeneity of the photonic crystals results in the Bloch surface wave sensors outperforming the surface plasmon polariton sensors by a factor 1.7 in terms of figure of merit. Considerations on the illumination bandwidth indicate options to further increase such a factor. © 2012 Elsevier B.V
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Hydrogenated amorphous silicon nitride photonic crystals for improved-performance surface electromagnetic wave biosensors
No full textWe exploit the properties of surface electromagnetic waves propagating at the surface of finite one dimensional photonic crystals to improve the performance of optical biosensors with respect to the standard surface plasmon resonance approach. We demonstrate that the hydrogenated amorphous silicon nitride technology is a versatile platform for fabricating one dimensional photonic crystals with any desirable design and operating in a wide wavelength range, from the visible to the near infrared. We prepared sensors based on photonic crystals sustaining either guided modes or surface electromagnetic waves, also known as Bloch surface waves. We carried out for the first time a direct experimental comparison of their sensitivity and figure of merit with surface plasmon polaritons on metal layers, by making use of a commercial surface plasmon resonance instrument that was slightly adapted for the experiments. Our measurements demonstrate that the Bloch surface waves on silicon nitride photonic crystals outperform surface plasmon polaritons by a factor 1.3 in terms of figure of meri
Probing losses of dielectric multilayers by means of Bloch surface waves
No full textWe exploit the excitation of electromagnetic surface waves on high-quality dielectric multilayers to measure the very low extinction coefficient of the structures, with a resolution down to 4.10(-7) and in a simple optical configuration. The effect of exposition to a rhodamine 6G solution in water and ethanol is also reported, including dye adsorption in the layers and bleaching upon resonant excitation. (C) 2013 Optical Society of Americ
Combining label-free and fluorescence operation of Bloch surface wave optical sensors
Full text linkWe report on the design, fabrication, and characterization of optical sensors based on Bloch surface waves propagating at the truncation edge of one-dimensional photonic crystals. The sensors can be simultaneously operated in both a label-free mode, where small refractive index changes at the surface are detected, and a fluorescence mode, where the fluorescence from a novel heptamethyne dye label in the proximity of the surface is collected. The two modes operate in the near-infrared spectral range with the same configuration of the optical reading apparatus. The limit of detection is shown to be smaller than that of equivalent surface plasmon sensors and the fluorescence collection efficiency is such that it can be efficiently analyzed by the same camera sensor used for label-free operation. (C) 2014 Optical Society of Americ
- …
