1,721,028 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Get PDFThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Get PDF“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Appropriate Similarity Measures for Author Cocitation Analysis
Get PDFWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
In silico designing of thermostabe β-Glucuronidase (GUS)
No full textThis research has used Molecular Dynamics (MD) techniquess as an in silico method of correlating the experimental studies done on GUS enzyme with computational study and has analyzed and identified the structural factors responsible for thermostability of this enzyme. GUS from E. coli is heat labile and inhibited by detergents and products, which hinder its usefulness as a reporter molecules in genetic
engineering. Therefore a more thermostable GUS enzyme needs to be designed for industrial applications. Using homology modeling, structures of mesophilic and thermophilic GUS enzymes from E. coli and T. maritima have been constructed based on the crystal structure of human GUS enzyme. MD
simulations of these mesophilic and thermophilic GUS enzymes at temperatures of 300 K and 353 K in vacuum and implicit solvent have provided information on thermolabile regions in the enzymatic structure to be targeted for thermal stability. The RMS deviation of backbone atoms and helical residues from their initial coordinates was analysed for the resulting simulation trajectories. A higher number of charged residues found in the thermostable GUS were found to be responsible for stability of the helices compared to mesophilic GUS. From analysis of salt bridges, the presence of higher number of Glu-Arg and Glu-Lys salt bridge pairs were found to be responsible for be responsible for thermostability of T.maritima GUS The thermolabile residues 150-155 in wild type E. coli GUS structures were identified, and have been suggested as mutation points for experimental studies to improve thermostability. These residues have not been identified before, and are suggested to be replaced with Ala, Arg, Glu, and Lys. The choice of Ala and Arg are supported by previous experimental mutations in other regions of GUS and
have resulted in thermostable GUS enzymes
Homology modelling and structural analysis of Phytases
No full textHomology modeling is a powerful tool in predicting the three dimensional (3D) structure of a protein using a solved structure within the same family as template. Compared to other methods such as X-ray crystallography and NMR, homology modelling has the advantage of being a fast yet reliable technique in solving proteins’ 3D structures, starting from their amino acid sequences. In this study, homology modelling was used to obtain the 3D structure of two different phytases using only their amino acid
sequence; phyFAUIA1_H which belongs to the histidine acid phosphatases, and Bacillus subtilis SAUIA243 which belongs to the β-propeller phytases. E. coli phytase (PDB code 1dkm) was used as a template for phyFAUIA1_H model with 99.512% sequence identity. On the other hand, Bacillus
amyloliquefaciens (PDB code 2poo) was used as a template for B. subtilis SAUIA243 model with 71.268% sequence identity. The BLAST (Basic Local Alignment Search Tool) algorithm was used to find the highest scoring ungapped local alignment between the query and database sequences. This particular score uses the BLOSUM substitution matrix, which is a block substitution matrix that uses segments of
blocks corresponding to the most highly conserved regions of proteins. Both models were evaluated and found to be quite satisfactory without being manually modified. Phytases are important constituents in Animal feed industry. These models can now be used to design new phytases, with improve properties such as enhanced enzyme activity, pH tolerance, and thermostability
Dispelling the Myths Behind First-author Citation Counts
Get PDFWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
koamabayili/VECTRON-author-checklist: VECTRON author checklist
No full textWe have done our best to complete the author checklist relating to the use of animals in the hut study. Note that the objective for the hut study was to evaluate the IRS treatment applications for residual efficacy against Anopheles mosquitoes, including the local An. coluzzii mosquito population. Cows were only used to attract mosquitoes into the huts and no tests were carried out directly on the cows. The author checklist is intended for use with studies where experiments are carried out on animals, which is why we have had such difficulty in completing this for the hut study, as many of the questions do not relate to how the cows were used
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