19 research outputs found
Supplemental Material, jacobijipactest1addmat - “My Friend with HIV Remains a Friend”: HIV/AIDS Stigma Reduction through Education in Secondary Schools—A Pilot Project in Buea, Cameroon
No full textSupplemental Material, jacobijipactest1addmat for “My Friend with HIV Remains a Friend”: HIV/AIDS Stigma Reduction through Education in Secondary Schools—A Pilot Project in Buea, Cameroon by Christoph Arnim Jacobi, Pascal Nji Atanga, Leonard Kum Bin, Akenji Jean Claude Fru, Gerd Eppel, Victor Njie Mbome, Hannah Etongo Mbua Etonde, Johannes Richard Bogner and Peter Malfertheiner in Journal of the International Association of Providers of AIDS Care (JIAPAC)</p
Supplemental Material, jacobijipactest2addmat - “My Friend with HIV Remains a Friend”: HIV/AIDS Stigma Reduction through Education in Secondary Schools—A Pilot Project in Buea, Cameroon
No full textSupplemental Material, jacobijipactest2addmat for “My Friend with HIV Remains a Friend”: HIV/AIDS Stigma Reduction through Education in Secondary Schools—A Pilot Project in Buea, Cameroon by Christoph Arnim Jacobi, Pascal Nji Atanga, Leonard Kum Bin, Akenji Jean Claude Fru, Gerd Eppel, Victor Njie Mbome, Hannah Etongo Mbua Etonde, Johannes Richard Bogner and Peter Malfertheiner in Journal of the International Association of Providers of AIDS Care (JIAPAC)</p
Supplemental Material, jacobijipacunaidsusergaddmat - “My Friend with HIV Remains a Friend”: HIV/AIDS Stigma Reduction through Education in Secondary Schools—A Pilot Project in Buea, Cameroon
No full textSupplemental Material, jacobijipacunaidsusergaddmat for “My Friend with HIV Remains a Friend”: HIV/AIDS Stigma Reduction through Education in Secondary Schools—A Pilot Project in Buea, Cameroon by Christoph Arnim Jacobi, Pascal Nji Atanga, Leonard Kum Bin, Akenji Jean Claude Fru, Gerd Eppel, Victor Njie Mbome, Hannah Etongo Mbua Etonde, Johannes Richard Bogner and Peter Malfertheiner in Journal of the International Association of Providers of AIDS Care (JIAPAC)</p
Supplemental Material, jacobijipacunaidsquestaddmat - “My Friend with HIV Remains a Friend”: HIV/AIDS Stigma Reduction through Education in Secondary Schools—A Pilot Project in Buea, Cameroon
No full textSupplemental Material, jacobijipacunaidsquestaddmat for “My Friend with HIV Remains a Friend”: HIV/AIDS Stigma Reduction through Education in Secondary Schools—A Pilot Project in Buea, Cameroon by Christoph Arnim Jacobi, Pascal Nji Atanga, Leonard Kum Bin, Akenji Jean Claude Fru, Gerd Eppel, Victor Njie Mbome, Hannah Etongo Mbua Etonde, Johannes Richard Bogner and Peter Malfertheiner in Journal of the International Association of Providers of AIDS Care (JIAPAC)</p
Retention-in-care, adherence and treatment outcomes in a cohort of HIVpositive pregnant and breastfeeding women enrolled in a pilot project implementing “Option B+” in Cameroon
No full textIntroduction:
Retention-in-care and adherence to lifelong antiretroviral therapy (ART) are major requirements to successfully optimise treatment benefits. We assessed linkage and retention-in-care with adherence and determinants of poor adherence along the PMTCT cascade in HIV-positive pregnant and breastfeeding women initiating option B+ in Cameroon.
Materials and Methods:
We prospectively determined uptake of HIV testing and counselling (HTC), uptake of ART, retention-in-care and adherence after Option B+ initiation between October 2013 and December 2014 in pregnant and breastfeeding women from five sites within the Kumba Health District. Retention-in-care was assessed over at least 12 months follow-up and estimated by Kaplan Meier analysis. Adherence at 12 months was determined for women retained in care using a composite adherence score. During follow-up, tracing outcomes and reasons for discontinuing treatment were documented and adherence measured.
Results:
Uptake of HTC in 5,813 women with unknown HIV status was 98.5% and ART uptake in women eligible to start Option B+ was 96.8%. We enrolled 268 women initiating lifelong ART in the follow up. Overall, 65 (24.3%) discontinued treatment, either defined by loss to follow-up 29(44.6%) or actively stopped treatment 36(55.8%). Retention-in-care was 88.0% and 81.1% at 6 and 12 months, respectively. Discontinuation was significantly associated in multivariate analysis with small sites and high staff turnover [aOR 2.5 (95% CI 1.6, 3.9), p < 0.001]. At 12 months 88.6% of women retained in care had good treatment adherence. After adjusting for confounders, younger age, attending a Pentecostal church, low level of education and employment in the informal sector significantly predicted poor adherence.
Conclusion:
Twelve months retention-in-care and adherence for women retained were 81.1% and 88.6% respectively. Retention-in-care was lowest at small facilities with a high staff turnover while adherence was poor for younger, women with low level of education, attending Pentecostal churches and employed in the informal sector
Factors associated with the occurrence of drug resistance mutations in ART-experienced patients.
No full textFactors associated with the occurrence of drug resistance mutations in ART-experienced patients.</p
Phylogenetic analysis of the HIV-1 pol region based on neighbour-joining methods was constructed with MEGA X software.
No full textThe codes of the reference sequences have the acronym “Ref.” at the end. The HIV-1 subtype for each sequence is written at the beginning of the code followed by the sample number in the bitwise sign. (For example D|56479|. Where D is the subtype and |56479| is the sample code).</p
Resistance patterns of the 25 sequences with nucleoside reverse transcriptase inhibitor (NRTI) mutations analyzed on the Stanford HIV database.
No full textResistance patterns of the 25 sequences with nucleoside reverse transcriptase inhibitor (NRTI) mutations analyzed on the Stanford HIV database.</p
Factors associated with the occurrence of drug resistance-associated mutations in ART-naive patients.
No full textFactors associated with the occurrence of drug resistance-associated mutations in ART-naive patients.</p
Baseline characteristics of study participants (n = 239).
No full textBaseline characteristics of study participants (n = 239).</p
