1,726,782 research outputs found
Public health aspects of Fusarium mycotoxins in food in The Netherlands : a risk assessment
No full textPlant pathogenic Fusarium moulds occur world-wide and cereals can become infected during the growing period. Fusarium was detected in 83 % of 69 cereal samples of batches intended for food or feed production and harvested in The Netherlands in 1993. A considerable genotypic and phenotypic variation was observed within two of the most frequently isolated Fusarium species. Mycotoxins can be excreted in the crop by the fungus after the plant becomes infected. A literature review revealed 137 secondary metabolites that could be, produced by Fusarium species which were isolated from food raw materials. Twelve of those secondary metabolites were identified as mycotoxins based on toxicity observed in test animals. Six of those twelve have possibly been involved in human disease outbreaks (T-2 toxin, nivalenol, deoxynivalenol, acetyldeoxynivalenol, fumonisin B1 and zearalenone). Most of the mycotoxins are stable under process conditions used for food production and can be detected in food. Cereals harvested in The Netherlands in 1993 were contaminated with deoxynivalenol (food poisoning and immunotoxic), 3 %, or zearalenone (oestrogen), 1 %. Fumonisin B 1 (carcinogenic, related to human oesophageal cancer) was detected in 98 % of samples of maize from batches imported in The Netherlands and intended for food production. A 28-day toxicity study on the effects of fumonisin B 1 in rats revealed dose-response related apoptosis in the kidney. The lowest observed effect level was at 0.19 mg fumonisin B 1 kg -1rat body weight. The data on fumonisin B 1 toxicity were used to estimate a tolerable daily intake (TDI) of 500 ng fumonisin B 1 kg -1human body weight. The probability of being daily exposed to fumonisin B 1 at a level corresponding to this TDI was 12 % for the people in The Netherlands consuming the average amount of maize, 55 % for people belonging to the group of 'eaters only' and 78 % for people with gluten intolerance. The health of the consumers in The Netherlands might, in the current situation, be challenged by Fusarium mycotoxins present in food. Deoxynivalenol, which has immunotoxic characteristics, can potentially be present in food and feed and might increase human exposure to infectious diseases, especially to those from zoonotic origin
Creatieve visualisatie in de instrumentles
No full textLuc Nijs en Marc Leman beschrijven een onderzoeksproject waarin gewerkt werd rond Creatieve visualisatie in de instrumentles. Binnen dit project werd de Music Paint Machine ontwikkeld en geïntroduceerd in het Deeltijds Kunstonderwijs. Het on- derzoek vond zijn inspiratie in de dagelijkse lespraktijk en werd verder ontwikkeld op basis van een constante interactie tussen een theoretisch, technologisch en empirisch kader. In deze bijdrage kan de lezer ontdekken hoe de integratie van technologie op een systematische manier kan worden ingebed en onderzocht in een bestaande lespraktijk
Muller De Nijs, Elly And Wim (Mrs & Mr), East Sumatra
No full textThis record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/406653Surname: MULLER DE NIJS. Given Name(s) or Initials: ELLY AND WIM (MRS & MR). Military Service Number or Last Known Location: EAST SUMATRA. Missing, Wounded and Prisoner of War Enquiry Card Index Number: 21767.248113
Item: [2016.0049.38930] "Muller De Nijs, Elly And Wim (Mrs & Mr), East Sumatra
LANDSCAPE : a big shift in society - growing complexity and the innovation opportunity
No full textThis chapter answers the question: Why do we need new approaches such as Imagineering? The answer to this question turns out to be simple and clear: Because with growing connectivity comes growing complexity. The chapter starts with an explanation of the difference between complicated and complex issues. Then it explains how hyperconnectivity brings forth not only VUCA (volatility, uncertainty, complexity and ambiguity) challenges but also important network opportunities, such as increasing the possibilities for value creation and enabling learning. The main part of this chapter focuses on the big shift in value creation in society and the opportunities that this brings for the operating logic. The implication is that we need to rethink marketing and managerial logic. There is an opportunity to reframe value creation from profit to purpose and to build better business for a better world. The chapter closes by reflecting on the complex innovation challenge that stems from this opportunity. We need new innovation logic.</p
De coach, de begeleider van de laatste mens?
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93648.pdf (Publisher’s version ) (Open Access)Radboud Universiteit Nijmegen, 25 juni 2012Promotores : Bos, R. ten, Nijs, W.F. de309 p
La traducció del «Tirant lo Blanch» en neerlandès
No full textBob de Nijs exposes some considerations about possible sources of different episodis of Tirant lo Blanch which arose when preparing the translation into Dutch. De Nijs focuses basically on the coincidences in the argument (the burial of both lovers in Brittany, for instance) and in the re-use of the characters (the Fresian king or Pyramus, Diafebus 's shield bearer) between the Tirant and Tristan et Iseut, which is one of the landmarks of the literature created in Brittany. The last part of the study analyses the influences of the ecclesiastic liturgy in some episodis in Constantinople. As an introduction, the Belgian translator summarises the preliminary stages of his work and exposes shortly the social and linguistic situation of the Dutch speakers who are divided into different states
Employee ownership and human resource management. A theoretical and empirical treatise with a digression on the Dutch context
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45250.pdf (Publisher’s version ) (Open Access)Radboud Universiteit Nijmegen, 20 december 2006Promotor : Nijs, W.F. de Co-promotor : Poutsma, F.XVIII, 173 p
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