241 research outputs found
Correction to: Real-World Predictors of Major Adverse Cardiovascular Events and Major Adverse Limb Events Among Patients with Chronic Coronary Artery Disease and/or Peripheral Arterial Disease (Advances in Therapy, (2020), 37, 1, (240-252), 10.1007/s12325-019-01132-z)
No full text© 2020, Springer Healthcare Ltd., part of Springer Nature. In the original article, the third author name is incorrect. The correct name is Nicholas J. Leeper. The original version of this article was revised
sj-pdf-1-vmj-10.1177_1358863X211067564 – Supplemental material for Development of a polygenic risk score to improve detection of peripheral artery disease
No full textSupplemental material, sj-pdf-1-vmj-10.1177_1358863X211067564 for Development of a polygenic risk score to improve detection of peripheral artery disease by Fudi Wang, Ilies Ghanzouri, Nicholas J Leeper, Philip S Tsao and Elsie Gyang Ross in Vascular Medicine</p
The Role of Necroptosis in Atherosclerotic Disease
No full textSummaryIt is now known that cells do not always die by apoptosis, but can also undergo a process known as programmed cell necrosis, or necroptosis. In a study recently published in Science Advances, investigators reported that this proinflammatory process is active in human atherosclerosis, may promote growth of the necrotic core, and may serve as a novel molecular imaging and translational therapeutic target. These findings represent a major step in our goal to reduce coronary disease and stroke
sj-pdf-1-vmj-10.1177_1358863X20987551 – Supplemental material for 2021 ACC/AHA/SVM/ACP Advanced Training Statement on Vascular Medicine (Revision of the 2004 ACC/ACP/SCAI/SVMB/SVS Clinical Competence Statement on Vascular Medicine and Catheter-Based Peripheral Vascular Interventions)
No full textSupplemental material, sj-pdf-1-vmj-10.1177_1358863X20987551 for 2021 ACC/AHA/SVM/ACP Advanced Training Statement on Vascular Medicine (Revision of the 2004 ACC/ACP/SCAI/SVMB/SVS Clinical Competence Statement on Vascular Medicine and Catheter-Based Peripheral Vascular Interventions) by Mark A. Creager, Naomi M. Hamburg, Keith D. Calligaro, Ana I. Casanegra, Rosario Freeman, Phyllis A. Gordon, Heather L. Gornik, Esther S.H. Kim, Nicholas J. Leeper, Geno J. Merli, Khusrow Niazi, Jeffrey W. Olin, Rene Quiroz, Elona Rrapo Kaso, Suman Wasan, Andrew R. Waxler, Christopher J. White, Khendi White Solaru, Marlene S. Williams, James A. Arrighi and Lisa A. Mendes in Vascular Medicine</p
sj-pdf-2-vmj-10.1177_1358863X20987551 – Supplemental material for 2021 ACC/AHA/SVM/ACP Advanced Training Statement on Vascular Medicine (Revision of the 2004 ACC/ACP/SCAI/SVMB/SVS Clinical Competence Statement on Vascular Medicine and Catheter-Based Peripheral Vascular Interventions)
No full textSupplemental material, sj-pdf-2-vmj-10.1177_1358863X20987551 for 2021 ACC/AHA/SVM/ACP Advanced Training Statement on Vascular Medicine (Revision of the 2004 ACC/ACP/SCAI/SVMB/SVS Clinical Competence Statement on Vascular Medicine and Catheter-Based Peripheral Vascular Interventions) by Mark A. Creager, Naomi M. Hamburg, Keith D. Calligaro, Ana I. Casanegra, Rosario Freeman, Phyllis A. Gordon, Heather L. Gornik, Esther S.H. Kim, Nicholas J. Leeper, Geno J. Merli, Khusrow Niazi, Jeffrey W. Olin, Rene Quiroz, Elona Rrapo Kaso, Suman Wasan, Andrew R. Waxler, Christopher J. White, Khendi White Solaru, Marlene S. Williams, James A. Arrighi and Lisa A. Mendes in Vascular Medicine</p
Adams family values: Abigail and Louisa Catherine Adams and the influence of Europe on the 'Republican Courts' of New York, Philadelphia, and Washington D.C. (1789-1829): Adams family values
No full textThis dissertation examines the writings and the cultural, social, and political actions of Abigail Adams and her daughter-in-law Louisa Catherine Adams, in an effort to further our understanding of the ‘republican courts’ in the early federal capitals of the United States. By examining the influence of European court life on these two women, as well as their complicated and comparative interests in monarchical aesthetics and etiquette, we can better understand why and how they attempted to transfer monarchical Europe’s social hierarchies, ceremonies, protocols, and material aesthetics into the United States capital. This dissertation argues that these efforts were extremely controversial in light of the fact that America had just separated itself from Europe and its royalist traditions. Consequently, the elite actions of the Adams women had a long-lasting impact not only on the reelection outcomes of John Adams and John Quincy Adams, but also on the larger narrative of American political and cultural history. The republican court is still a rarely acknowledged term in the historiographies of the early United States, yet as this dissertation makes clear, this term best describes the social and cultural scene of New York, Philadelphia, and early Washington D.C. from 1789 to the rise of Jackson in 1829, and that the Adams women were the most significant adopters of those European traditions. By reconsidering the Adams women as major key players and facilitators of the republican court, we must conclude that the Adams women were far more complex political figures than has previously been suggested, and because of their efforts, European court culture and high society traditions played a far larger role in the founding of the American government than has previously been realized
Characterization of the Mt. Simon Sandstone in Southwest Ohio for CO2 Sequestration
No full textCO2 sequestration in deep subsurface environments has been proposed as an innovative strategy to lessen the impact of burning fossil fuels on Earth’s atmosphere. In order for CO2 sequestration to be effective, the target formation must have sufficient porosity, permeability, depth and thickness to store CO2. The Mt. Simon Sandstone, a Cambrian arenite to arkosic sandstone in western Ohio may provide appropriate physical and mineralogical properties for effective CO2 sequestration. The goal of this research is to evaluate the Mt. Simon sandstone’s volumetric capacities including connected porosity, pore size and pore volume, as well as to determine mineralogy and digenetic processes, to assess the formation’s suitability for CO2 sequestration. Samples and measurements were performed on the ODGS 2627 Warren well, and on the ODGS 2843 Armco well to evaluate spatial continuity and vertical heterogeneity.
Porosity and pore size distribution measurements were determined using mercury porosimetry and BET gas sorption. Grain size measurements were determined through the use of light microscopy. Results show a porosity range of 1-25%, a connected pore size range of 5-1612 nm, and a decrease in grain size from the base of the Mt. Simon Sandstone through the overlying Eau Claire Formation. Variations in porosity and pore size show that the formation is heterogeneous, changing substantially on a macro scale. Changes in grain size are representative of a transgressive depositional system.
Mineralogical characterization of the target Mt. Simon Sandstone and surrounding formations used powder X-ray diffraction, SEM, and polarized light microscopy to show lithologic variations from arenite to feldspathic sandstone, with cementation that included quartz, illite, chlorite, carbonate, iron and titanium oxides, and iron sulfides. Results show heterogeneity in each formation that occurs laterally. Comparison of lithology and pore space reveals that mineralogy and diagenetic processes are the main factors controlling available pore space, and that clean quartz arenite provide the greatest porosity. CO2 storage calculations show that the Warren well location could hold up to 61.0 million metric tons, however this would not provide enough storage space to sustain a long term coal fire power plant.No embarg
Figure 1: Necroptosis in Cardiovascular Disease
No full textLDL = low-density lipoprotein; TNF = tumor necrosis factor
Recommended from our members
Indian Fishing Contrivances / A Female Crusoe
No full textFish have long been recognized as having once comprised a particularly critical resource for native groups in many areas of California, and the various techniques employed in their extraction —whether from the ocean, rivers and streams, or lakes—were often both sophisticated and effective. The first account presented here (perhaps half of which is from previously published sources) provides a wealth of significant data, both old and new, on the construction and use of fish weirs in catching salmon in some of the state's major rivers. Parenthetically, it should be noted that the weirs described by Ringgold and Bidwell on the Sacramento River were entirely different structures, and were actually separated by some miles. The author and compiler, David R. Leeper, came to California during the gold rush, and later recounted his adventures and observations in The Argonauts of ‘Forty- Nine (1894). The article reprinted here was originally published in The American Archaeologist [Volume 2, Part 9, Sept 1898, pp. 227-230.] Leeper also contributed a number of other short articles on California Indians to The American Archaeologist and its predecessor The Antiquarian. The second account adds some additional historical context to the familiar story of the Lone Woman of San Nicholas, and makes it clear that her presence on the island and some details of her life there were well known years before her 'recovery' by George Nidever in 1853. It originally appeared in Boston's Daily Atlas on March 27, 1847.1am indebted to Steven Schwartz of the Point Mugu Naval Air Station Environmental Division for bringing this to my attention
- …
