4,840 research outputs found
The use of machine learning to identify the correctness of HS Code for the customs import declarations
No full textAs an increasing volume of international trade activities around the world, the amount of cross-boarder import declarations grows rapidly, resulting in an unprecedented scale of potentially fraudulent transactions, in particular false commodity code (e.g., HS Code). The incorrect HS Code will cause duty risk and adversely impact the revenue collection. Physical investigation by the customs administrations is impractical due to the substantial quantity of declarations. This paper provides an automatic approach by harnessing the power of machine learning techniques to relief the burden of customs targeting officers. We introduced a novel model based on the off-the-shelf embedding encoder to identify the correctness of HS Code without any human effort. Determining whether the HS Code is correctly matched with commodity description is a classification task, so the labelled data is typically required. However, the lack of gold standard labelled data sets in customs domain limits the development of supervised-based approach. Our model is developed by the unsupervised mechanism and trained on the unlabelled historical declaration records, which is robust and able to be smoothly adapted by the different customs administrations. Rather than typically classifying whether the HS Code is correct or not, our model predicts the score to indicate the degree of the HS Code being correct. We have evaluated our proposed model on the ground-truth data set provided by Dutch customs officers. Results show promising performance of 71% overall accuracy.Green Open Access added to TU Delft Institutional Repository ‘You share, we take care!’ – Taverne project https://www.openaccess.nl/en/you-share-we-take-care Otherwise as indicated in the copyright section: the publisher is the copyright holder of this work and the author uses the Dutch legislation to make this work public.Information and Communication Technolog
HS-stability and complex products in involution semigroups
No full textWhen does the complex product of a given number of subsets of a group generate the same subgroup as their union? We answer this question in a more general form by introducing HS-stability and characterising the HS-stable involution subsemigroup generated by a subset of a given involution semigroup. We study HS-stability for the special cases of regular ∗-semigroups and commutative involution semigroups.</p
An Investigation of First-Year English Majors’ Ability for Independent Study Through Use of Online Vocabulary-Learning Tools at Nguyen Tat Thanh University
No full textThis research examines independent study techniques, particularly those aided by technology, used by students majoring in English in their first year at Nguyen Tat Thanh University in Vietnam, with a focus on their study of vocabulary. English majors in particular used a variety of online tools to achieve a wide range of vocabulary in order to reach higher levels of language proficiency. Using a mixed-methods approach and an AI tool, Random Forest Regressor, this study aimed to identify the most frequently chosen online vocabulary tools and the factors influencing their use for independent study. It would also evaluate students’ aptitudes for self-directed learning, identify successful strategies, and recommend ways to foster independent learning through the use of technology. The findings highlight that independent study enhances academic outcomes critical thinking, and vocabulary learning autonomy
Improved current drivability and gate stack integrity using buried SiC layer for strained Si/SiGe channel devices
No full textSTRATEGI PEMASARAN TOKO KERAJINAN PERAK HS SILVER KOTAGEDE
No full textHS Silver is one of silversmithing shop, Yogyakarta. This silver craft store
has a huge potential in Kotagede because it has a silver shop workshop tour packages
for tourists who come.
The purpose of this study was to analyze the marketing strategy of the HS
Silver shop silver and supporters know and inhibiting HS Silver shop silver. The
author also wants to know what marketing has done for store promotions HS Silver
silver Kotagede. In this study the authors obtain the data or information by means of
direct observation to the field, then do the documentation to obtain a variety of
written documents or data objects as well as images of other photographs that exist in
the object, in addition, the authors also conducted interviews with sources, namely
Silver and HS staff marketing HS Silver.
Store silver Silver HS has some constraints in the face of marketing. In any
tourism marketing are common constraints, but these constraints can be overcome.
For customer convenience HS Silver should still give priority to the user in the face
of the customer
Registration of (HS-182) and (HS-183) food grade soybean (Glycine max [L.] Merr.) Germplasm
No full textHS-182 and HS-183 are food-grade soybean lines [Glycine max (L.) Merr.] with distinct seed protein profiles and food processing quality. HS-182 is a 7S β-conglycinin α’ and 11S glycinin A4 null with a high protein concentration of 45.7% and good processing quality. HS-183 is a 7S β-conglycinin α’ and 11S glycinin null with a protein concentration of 42.7% and poor tofu processing quality. They are adapted to areas of southwestern Ontario with 3100 or more crop heat units and have relative maturity groups of 2.5 and 2.4, respectively.The accepted manuscript in pdf format is listed with the files at the bottom of this page. The presentation of the authors' names and (or) special characters in the title of the manuscript may differ slightly between what is listed on this page and what is listed in the pdf file of the accepted manuscript; that in the pdf file of the accepted manuscript is what was submitted by the author
Medical and Surgical Management of Hidradenitis Suppurativa: A Review of International Treatment Guidelines and Implementation in General Dermatology Practice
No full textBackground: Hidradenitis suppurativa (HS) is a chronic painful skin disease that severely impairs patients' quality of life. While high-quality trials of HS therapies remain limited, medical knowledge of best treatment practices is rapidly evolving, leading to the recent publication of multiple international treatment guidelines for HS. Summary: This review compares international HS treatment guidelines, describes evidence for effectiveness of common and emerging HS therapies, and provides guidance for integrating evidence-based HS care into practice. Although over 50 medical and procedural treatments are mentioned across international HS guidelines, only adalimumab and infliximab have grade B/weak recommendation or higher across all major guidelines. This review describes the appropriate patient selection and effectiveness of the most commonly used medical and procedural treatments for HS. It also includes recommendations for counseling, dosing, and duration of medical therapies as well as procedure videos for the practicing dermatologist
Hidradenitis suppurativa: an update on epidemiology, phenotypes, diagnosis, pathogenesis, comorbidities and quality of life
No full textHidradenitis suppurativa (HS) is a chronic inflammatory skin disease that severely impairs patients' quality of life. It is characterized by recurrent painful nodules, abscesses and draining sinus tracts in primarily intertriginous areas. We aimed to review the most up-to-date information regarding the epidemiology, clinical presentation, diagnostic studies, pathogenesis, comorbidities and quality of life of patients with hidradenitis suppurativa. We performed a systematic search of Medline, Embase database (from inception to September 2019) and review of bibliographies without restrictions on year or language. HS has an estimated global prevalence of 0.00033–4.1% (but most likely 0.7–1.2% in the European-US population). Patients still experience a significant diagnostic delay, up to several years. In the absence of pathognomonic tests, the diagnosis of HS is made from clinical observation and the disease narrative. Phenotypic variation renders diagnosis and severity assessment difficult. Ultrasound imaging is an emerging assessment tool for deep-seated lesions. The Hurley Staging System is still widely used in severity rating. Follicular hyperkeratosis and dilatation, follicular rupture and chronic inflammation with architectural tissue changes have been implicated in the pathogenesis of HS. HS has been associated with metabolic syndrome and other risk factors for cardiovascular disease, diabetes mellitus type II, polycystic ovarian syndrome, depression, suicide and substance use disorders. It has been linked to other immune-mediated diseases such as inflammatory bowel disease and spondyloarthropathy. Pain, pruritus, malodour, low self-esteem, sleep and sexual dysfunctions, and poor mental health are chronic symptoms or consequences of uncontrolled disease. HS is an under-diagnosed and under-treated disease with a profound negative impact on patients' quality of life. In the light of its associated comorbidities, an interdisciplinary management approach may be needed to ensure the best outcomes
HS-1371, a novel kinase inhibitor of RIP3-mediated necroptosis
No full textNecroptosis is a type of programmed cell death that usually occurs under apoptosis-deficient conditions. Receptor-interacting protein kinase-3 (RIP3, or RIPK3) is a central player in necroptosis, and its kinase activity is essential for downstream necroptotic signaling events. Since RIP3 kinase activity has been associated with various diseases, the development of specific RIP3 inhibitors is an attractive strategy for therapeutic application. In this study, we identified a potent RIP3 inhibitor, HS-1371, by the extensive screening of chemical libraries focused on kinases. HS-1371 directly binds to RIP3 in an ATP-competitive and time-independent manner, providing a mechanism of action. Moreover, the compound inhibited TNF-induced necroptosis but did not inhibit TNF-induced apoptosis, indicating that this novel inhibitor has a specific inhibitory effect on RIP3-mediated necroptosis via the suppression of RIP3 kinase activity. Our results suggest that HS-1371 could serve as a potential preventive or therapeutic agent for diseases involving RIP3 hyperactivation © The Author(s) 201
Acquisition of plasmid with carbapenem-resistance gene blaKPC2 in hypervirulent Klebsiella pneumoniae, Singapore
No full textThe convergence of carbapenem-resistance and hypervirulence genes in Klebsiella pneumoniae has led to the emergence of highly drug-resistant superbugs capable of causing invasive disease. We analyzed 556 carbapenem-resistant K. pneumoniae isolates from patients in Singapore hospitals during 2010-2015 and discovered 18 isolates from 7 patients also harbored hypervirulence features. All isolates contained a closely related plasmid (pKPC2) harboring blaKPC-2, a K. pneumoniae carbapenemase gene, and had a hypervirulent background of capsular serotypes K1, K2, and K20. In total, 5 of 7 first patient isolates were hypermucoviscous, and 6 were virulent in mice. The pKPC2 was highly transmissible and remarkably stable, maintained in bacteria within a patient with few changes for months in the absence of antimicrobial drug selection pressure. Intrapatient isolates were also able to acquire additional antimicrobial drug resistance genes when inside human bodies. Our results highlight the potential spread of carbapenem-resistant hypervirulent K. pneumoniae in Singapore.National Medical Research Council (NMRC)Published versionThis work was supported by the National University of Singapore, Yong Loo Lin School of Medicine Aspiration Fund (NUHSRO/2014/068/AF New Idea/03), and National Medical Research Council (NMRC) collaborative grant Collaborative Solutions Targeting Antimicrobial Resistance Threats in Health Systems (CoSTAR-HS, HS/ARGSeedGrant/2017/03) to Y.-H.G. Additional grant support was provided by CoSTAR-HS (NMRC CGAug16C005), NMRC Clinician Scientist Award (NMRC/CSA-INV/0007/2016), and NMRC Clinician Scientist Award (MOH-000276)
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