1,721,039 research outputs found
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Effectiveness of fluoroscopy-guided manual lymph drainage for the treatment of breast cancer-related lymphedema
No full textAbstract: This general introduction comprises six different topics. In topic 1, more information will be provided about diagnosing breast cancer and its therapeutic approaches. The second topic will further explain lymphedema after the treatment for breast cancer. Thereafter, the rationale for the evaluation of breast cancer-related lymphedema will be elaborated in topic 3. In topic 4, different treatment modalities for breast cancer-related lymphedema will be discussed. Subsequently, the role of manual lymph drainage as a treatment modality for breast cancer-related lymphedema, is discussed in topic 5. At last, the specific aims and outlines of this doctoral thesis will be pointed out in topic 6
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Effectiviteit van fluoroscopie-gestuurde manuele lymfedrainage ter behandeling van borstkanker-gerelateerd lymfoedeem
No full textCurrently, almost all patients with breast cancer-related lymphedema (BCRL) receive manual lymph drainage (MLD) to treat the edema. Despite this worldwide application of MLD, different systematic reviews and meta-analyses conclude that there is no strong evidence about the effectiveness of lymph drainage to treat BCRL. Belgrado and colleagues developed a new and more efficient method of lymph drainage to improve lymph transport, i.e. fluoroscopy-guided MLD. Belgrado has already shown that MLD with relatively high pressure (vs lower pressure) is more effective to improve lymph transport, as well as gliding (vs no gliding). In this study, only the physiological effect after one session of fluoroscopy-guided MLD was investigated. Whether the application of different sessions of fluoroscopy-guided MLD as part of the intensive phase of Decongestive Lymphatic Therapy is clinically effective, has never been examined. Therefore, a randomised controlled trial will investigate the effect of fluoroscopy-guided MLD versus traditional MLD vs placebo MLD on several clinical parameters (primary: change in arm/hand volume and change in accumulation of fluid at level of the shoulder/trunk, and secondary: change in quality of life (QoL) and change in lymphedema-related functioning) in patients with BCRL. Other research objectives of this doctoral project are:
1) To compare five volumetric measurement methods in terms of reliability, time-efficiency, and clinical feasibility for assessing excessive arm volume in patients with BCRL: traditional volumetry with overflow, volumetry without overflow, inversed volumetry, opto-electronic volumetry and calculated volume based on circumferences.
2) To investigate and compare reliability of the MoistureMeterD® Compact device and the pitting test as clinical assessment tools for evaluating the water content and composition of edema, in patients BCRL.
3) To assess the clinimetric properties (validity, reliability and responsiveness) of the Dutch Lymph-ICF-UL questionnaire in patients with BCRL. Additionally, to translate the Dutch version of the Lymph-ICF-UL questionnaire into French, and to assess its clinimetric properties (validity and reliability) accordingly, in a cohort of French-speaking patients with BCRL.
4) To make a systematic review on the financial impact of BCRL treatment. Furthermore, to make a financial analysis of the direct costs related to BCRL and its sequelae, in a European setting.
These five research aims will be investigated through nine different studies representing nine chapters.status: Publishe
Cardiomyocytaire Contractiliteit, Calcium Huishouding en Endotheliale Functie in een muismodel van Type II Diabetes en het Metabool Syndroom
No full textDiabetes, obesity and dyslipidemia are associated with a significant increase in cardiovascular morbidity and mortality, caused by cardiomyopathy, vasculopathy and their consequences. The prevalence of affected patients is still increasing, resulting in a major health care problem.14.0pt;margin-left:0cm;text-align:justify;line-height:150%;text-autospace:ideograph-numeric" align="left">The existence of a primary diabetic cardiomyopathy, in the absence of an ischemic or hypertensive cardiomyopathy is at least partially related to alterations in cardiomyocyteproperties. Although it has been shown in vivo that cardiac dysfunctionis aggravated in the metabolic syndrome and characterized by additionalfeatures, -.1pt">changes in intrinsic properties of cardiomyocytes have not been studied in mice with the metabolic syndrome (MetS). 14.0pt;margin-left:0cm;text-align:justify;line-height:150%;text-autospace:ideograph-numeric" align="left">Diabeticangiopathy is characterized by abnormalities in vascular wall morphology and altered vascular reactivity. It is currently unclear whether the dyslipidemia and hypertension, associated with diabetes type II in MetS, worsen these diabetes-induced alterations in vascular function.-.1pt"> 14.0pt;margin-left:0cm;text-align:justify;line-height:150%;text-autospace:ideograph-numeric" align="left">-.1pt">Concerning therapy, 150%">hypocaloric diet and ACE-inhibitors arecurrently the golden standard in the treatment of cardiovascular complications in patients with diabetes mellitus type II and the metabolic syndrome. .5pt">However, most studies are performed with both entities in one group, exhibiting a large pathological and clinical variance-.1pt">. ideograph-numeric" align="left">-.1pt">This study was designed tline-height:150%;letter-spacing:-.1pt">o gain further insight into the mechanisms contributing to cardiovascular dysfunction in the metabolic syndrome and to.5pt"> study more in detail the effect of ACE-inhibitors and hypocaloric dieton cardiovascular function in d150%">iabetes type II and the metabolic syndrome.5pt">, as separate entities. ideograph-numeric" align="left">Cardiomyocyte function and Ca2+ handling in a mouse model of the metabolic syndrome. We have shown that cardiomyocyte function and Ca2+ handling are impaired in DKO mice (the used model of the metabolic syndrome), associated with reduced contractile reserve, compared to ob/ob mice. ACE-inhibition, but not weight reduction, can restore cardiomyocyte relaxation and β-adrenergic responsiveness. These data indicate that the in vivo features of cardiomyopathy in the metabolic syndrome can at least partially be explained by alterations in intrinsic cardiomyocyte properties and Ca2+ handling. Secondly, they indicate that dyslipidemia and/or hypertension in typeII diabetic mice aggravate cardiomyocyte dysfunction.14.0pt;margin-left:0cm;text-align:justify;line-height:150%;text-autospace:ideograph-numeric" align="left">Vascular reactivity in a mouse model of themetabolic syndrome.DKO mice show a more pronounced impairment of acetylcholine-induced vasorelaxation, compared to ob/ob. This effect is mainly NO-mediated and can be restored by ACE-inhibition and hypocaloric diet. In contrast, response to bradykinin is equally reduced in both genotypes and is not influenced by ACE-inhibition. These data suggest that dyslipidemia and hypertension aggravate NO-mediated endothelium-dependentrelaxation in type II diabetic mice, reversible by ACE-inhibition and diet. In contrast, these features prevent further worsening of bradykinin-induced vasorelaxation in type II diabetic mice. This effect might be mediated via endothelial COX-2 and can not be restored by ACE-inhibition.14.0pt;margin-left:0cm;text-align:justify;line-height:150%;text-autospace:ideograph-numeric" align="left">Taken together, this study shows that dyslipidemia and hypertension aggravate cardiovascular dysfunction in vitro in type II diabetic mice. ACE-inhibiton and hypocaloric diet can improve this impaired cardiovascular function.status: Publishe
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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