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Radionuclide renography predicts functional changes in patients with renal artery involvement by Takayasu's arteritis
Morpho-functional evaluation of hypertensive patients with renal artery stenosis. Correlations between angiography and dynamic scintigraphy
Radionuclide renography predicts functional changes in patients with renal artery involvement by Takayasu's arteritis
Diagnostic imaging in patients with paragangliomas. Computed tomography, magnetic resonance and MIBG scintigraphy comparison
Morpho-functional evaluation of hypertensive patients with renal artery stenosis. Correlations between angiography and dynamic scintigraphy
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Effects of atrial natriuretic peptide on glomerular filtration rate in essential hypertension: a radionuclide study
Anti-murine antibody response to mouse monoclonal antibodies: clinical findings and implications
Measurement of local Mr 97,000 and 250,000 protein antigen concentration in sections of human melanoma tumor using in vitro quantitative autoradiography.
An assay method that uses I25l-labeled monoclonal antibody (MoAb) and in vitro quantitative autoradiography was developed to determine the local concentration of tumor-associated antigens in tissue sections. Human melanoma biopsy specimens were evaluated for the expression of the M, 97,000 and 250,000 protein antigens using MoAb-96.5 and MoAb-9.2.27, respectively. Tissue sections were incubated in solutions of increasing concentration of I25l-labeled MoAb with or without an excess of unlabeled antibody. Quantitative autoradiography was performed on the sections and compared with I25I standards to determine tumor-bound radioactivity and calculate bound pmol of MoAb per g of tumor. The total binding, nonsaturable binding, and specific binding of I25l-labeled MoAb to tumor were then computed. Specific binding of MoAbs to tumor tissue was saturable in all antigen-positive tumors. The maximal concentration of specific binding of antibody to tissue (Bmax) represented the tissue antigen concentration. Estimates of the K, of antigen/antibody binding were also made. The reliability of the measurements was con firmed by testing sections from mixtures of antigen-positive and antigen-negative cells
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