101,765 research outputs found
Champsodon pantolepis Nemeth 1994
No full textChampsodon pantolepis Nemeth 1994 —Scaly champsodontid (Fig. 116) Status at New Ireland. New record, based NTUM 12157 (1 specimen, 67.9 mm SL, St. CP 4418-28, northeast of New Hanover). Distribution and habitat. New Ireland: 1.—General distribution: southern Japan; northern Western Australia. 340–406 m depth. Marine.Published as part of Andréfouët, Serge, Chen, Wei-Jen, Kinch, Jeff, Mana, Ralph, Russell, Barry C., Tully, Dean & White, William T., 2019, Checklist of the marine and estuarine fishes of New Ireland Province, Papua New Guinea, western Pacific Ocean, with 810 new records, pp. 1-360 in Zootaxa 4588 (1) on page 248, DOI: 10.11646/zootaxa.4588.1.1, http://zenodo.org/record/298816
Pittonotus iranicus Platia & Nemeth 2011
No full text<i>Pittonotus iranicus</i> Platia & Nemeth, 2011 <p>(Map 7)</p> <p> <b>Material examined</b> (HMIM). Khuzestan province: 1 ex.: Andika, Keveshk to Lalar rd., Shimbaar P.A., nr. Shimbaar lagoon, Shimbaar ranger station, N32°25’18.1” E49°36’10.8”, 917 m., 6. VI.2019, leg. H. Nasserzadeh (L. T.).</p> <p> <b>Climate types.</b> Semi-arid, with cool winters and very warm summers.</p> <p> <b>Distribution in Palaearctic Region.Asia:</b> Iran (Azarbaijan-e Sharghi, Fars, Khuzestan (first record), Kordestan and Lorestan provinces in western half of Iran) (Platia & Nemeth 2011; Nasserzadeh & Platia 2021).</p>Published as part of <i>Nasserzadeh, Hiva, Platia, Giuseppe & Serri, Sayeh, 2023, Click beetles (Coleoptera: Elateridae) of Khuzestan province (Iran): with three new species, Craspedostethus izehensis sp. n., Dicronychus khuzestanicus sp. n. and Gurjevelater catei sp. n., pp. 101-130 in Zootaxa 5346 (2)</i> on page 110, DOI: 10.11646/zootaxa.5346.2.1, <a href="http://zenodo.org/record/8354558">http://zenodo.org/record/8354558</a>
Letter, [Author unclear] to Paulina T. Merritt
No full textHandwritten letter to Paulina Merritt from an unknown author, October 1, 1876.
Research progress on metallothioneins: insights into structure, metal binding properties and molecular function by spectroscopic investigations
No full textMetallothioneins (MTs) are low molecular weight, cysteine-rich proteins with an exceptionally heavy metal coordination capacity. Because of their ability to bind metals and to scavenge oxidant radicals, MTs are considered to play a role in metal homeostasis, metal detoxification and control of the oxidative stress. Although their high heterogeneity on the expression patterns, metal binding abilities and primary structure suggest very diverse functional specializations, the structural and functional studies have been mainly devoted to vertebrate and fungal MTs and their canonical cysteine-metal clusters.
This chapter will be focused on the new methodological procedures settled for the structural characterisation of some metallic MT aggregates. Five zinc complexes of the invertebrate and plant MTs, poorly described up to now in the literature, in addition to one well studied MT from vertebrate family, will be analysed and the new discovered structural features of metal-MT clusters, together with the perspectives on MT research, will be commented. In fact, the application of several spectroscopic techniques such as Raman and IR spectroscopies, Circular Dichroism, can provide new structural information eventually related to the function of the metal binding.
Recombinant expression in E.coli has allowed the biosynthesis of intact metal-MT complexes, well corresponding to native forms, in sufficient quantity and purity for analytical spectrometric and spectroscopic characterization. The spectroscopic analyses of the in vivo-synthesised metal-MTs have recently demonstrated the participation of extra-protein ligands, such as chloride and sulfide ions, in the metal-MT coordination environment of vertebrate, invertebrate and plant MTs.
Recently, some new insights on the structure of metal-MT complexes has been obtained by using Raman and IR spectroscopies, powerful techniques in protein studies. Despite the potentialities of these techniques, to our knowledge they have been scarcely used in MT conformational studies until now. The use of these spectroscopies has resulted to be very useful to approach unambiguously two basic structural points poorly described in MTs: the participation of chloride, sulfide ions and His residues to the metal-coordination sphere and the presence of secondary structure elements. In particular, ordered secondary structures, oppositely to what has been commonly accepted, are present in MTs from vertebrate, invertebrate and plant MTs, and could develop crucial roles in the determination of the functional properties of MTs
Handwritten biographical information on Paulina T. McClung Merritt
No full textA handwritten biography of Paulina T. McClung Merritt by an unknown author, 1892.
Heterogeneous and tissue-specific regulation of effector T cell responses by IFN-gamma during Plasmodium berghei ANKA infection.
No full textIFN-γ and T cells are both required for the development of experimental cerebral malaria during Plasmodium berghei ANKA infection. Surprisingly, however, the role of IFN-γ in shaping the effector CD4(+) and CD8(+) T cell response during this infection has not been examined in detail. To address this, we have compared the effector T cell responses in wild-type and IFN-γ(-/-) mice during P. berghei ANKA infection. The expansion of splenic CD4(+) and CD8(+) T cells during P. berghei ANKA infection was unaffected by the absence of IFN-γ, but the contraction phase of the T cell response was significantly attenuated. Splenic T cell activation and effector function were essentially normal in IFN-γ(-/-) mice; however, the migration to, and accumulation of, effector CD4(+) and CD8(+) T cells in the lung, liver, and brain was altered in IFN-γ(-/-) mice. Interestingly, activation and accumulation of T cells in various nonlymphoid organs was differently affected by lack of IFN-γ, suggesting that IFN-γ influences T cell effector function to varying levels in different anatomical locations. Importantly, control of splenic T cell numbers during P. berghei ANKA infection depended on active IFN-γ-dependent environmental signals--leading to T cell apoptosis--rather than upon intrinsic alterations in T cell programming. To our knowledge, this is the first study to fully investigate the role of IFN-γ in modulating T cell function during P. berghei ANKA infection and reveals that IFN-γ is required for efficient contraction of the pool of activated T cells
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Pelevin’s Trinity in the novel “t”: author – protagonist – reader
No full textThe article attempts to interpret Pelevin's artistic strategy in the novel "T" by exploring its subject organization and addressing the key problems of the author, the protagonist, and the reader as they are seen by the researcher. The article analyzes the peculiarities of constructing the narrative reality in the novel "T", and goes on to discuss Pelevin's philosophic models of the development of the humankind, and the emergence of his new anthropology
Measuring industry-science links through inventor-author relations: A profiling method
No full textIn this pilot study we examine the performance of text-based profiling in recovering a set of validated inventor-author links. In a first step we match patents and publications solely based on their similarity in content. Next, we compare inventor and author names on the highest ranked matches for the occurrence of name matches. Finally, we compare these candidate matches with the names listed in a validated set of inventor-author names. Our text-based profile methodology performs significantly better than a random matching of patents and publications, suggesting that text-based profiling is a valuable complementary tool to the name searches used in previous studies.innovation; industry-science links; text-based profiling;
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