1,220 research outputs found
Colin Humphris
No full text"Colin Humphris 2 Sqdrn. RAAF. 1941 - 1942 Author of - 'Trapped on Timor' (as a result of bombing of Darwin Feb. 19, 1942)".Colin Humphris. 2 Squadron, Royal Australian Air Force 1941 - 1942. Author of - 'Trapped on Timor' (as a result of bombing of Darwin February 19, 1942)
Development of Fibrinogen-based Bioinks for 3D Bioprinting Motor Neuron Progenitor Cells
No full textIn the United States, there are more than 12,000 new cases of spinal cord injury each year. No effective treatment is available for these injuries except high-expense lifetime care. Here we introduce a fibrinogen-based bioink for the purpose of 3D bioprinting motor neuron progenitor cells (MNPCs) into hydrogel scaffolds as a potential treatment for major spinal cord injury. While other bioinks are commercially available, such as gelatin methylacrylate (GELMA) and Matrigel, a murine Engelbreth-Holm-Swarm (EHS) sarcoma extract, these bioinks are toxic to MNPCs and are not fully defined, respectively. For this reason, a fully defined bioink that is not toxic to MNPCs must be developed. The results suggest that the bioink developed for 3D bioprinting supports viability and differentiation of MNPCs, but the printing process that MNPCs go through while being extruded into hydrogel scaffolds must further be optimized to increase MNPC viability and differentiation.This research was supported by the Undergraduate Research Opportunities Program (UROP).Neitzke, Colin C. (2017). Development of Fibrinogen-based Bioinks for 3D Bioprinting Motor Neuron Progenitor Cells. Retrieved from the University Digital Conservancy, https://hdl.handle.net/11299/189536
Supporting data for 3D Printed Stem-Cell Derived Neural Progenitors Generate Spinal Cord Scaffolds
No full textThe ability to model CNS tissues in vitro for in vivo transplantation has the potential to be of critical importance in a variety of medical conditions such as spinal cord injury, traumatic brain injury, stroke, and degenerative neurologic disease. Our approach to generating functional CNS tissue constructs relies on a “multiprong” combination of sophisticated 3D bioprinting and cell culture expertise. Here, as an example for utilizing novel 3D neurobioprinting, we have devised a method to model the cytoarchitecture of spinal cord tissue.A bioengineered spinal cord is fabricated via extrusion-based multilateral 3D bioprinting, in which clusters of induced pluripotent stem cell (iPSC)-derived spinal neuronal progenitor cells (sNPCs) and oligodendrocyte progenitor cells (OPCs) are placed in precise positions within 3D printed biocompatible scaffolds during assembly. The location of a cluster of cells, of a single type or multiple types, is controlled using a point-dispensing printing method with a 200 μm center-to-center spacing within 150 μm wide channels. The bioprinted sNPCs differentiate and extend axons throughout microscale scaffold channels, and the activity of these neuronal networks is confirmed by physiological spontaneous calcium flux studies. Successful bioprinting of OPCs in combination with sNPCs demonstrates a multicellular neural tissue engineering approach, where the ability to direct the patterning and combination of transplanted neuronal and glial cells can be beneficial in rebuilding functional axonal connections across areas of central nervous system (CNS) tissue damage. This platform can be used to prepare novel biomimetic, hydrogel-based scaffolds modeling complex CNS tissue architecture in vitro and harnessed to develop new clinical approaches to treat neurological diseases, including spinal cord injury.Conquer Paralysis NowMinnesota Spinal Cord Injury and Traumatic Brain Injury Research Grant ProgramNational Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health (Award No. 1DP2EB020537)CTSI KL2 Scholar Program of the National Institutes of Health (Award No. NIHCON000000033119-3002)Joung, Daeha; Truong, Vincent; Neitzke, Colin C; Guo, Shuang-Zhuang; Walsh, Patrick J; Monat, Joseph R; Meng, Fanben; Park, Sung Hyun; Dutton, James R; Parr, Ann M; McAlpine, Michael C. (2020). Supporting data for 3D Printed Stem-Cell Derived Neural Progenitors Generate Spinal Cord Scaffolds. Retrieved from the University Digital Conservancy, https://doi.org/10.13020/femp-z102
Orbit design for future SpaceChip swarm missions in a planetary atmosphere
No full textThe effect of solar radiation pressure and atmospheric drag on the orbital dynamics of satellites-on-a-chip (SpaceChips) is exploited to design equatorial long-lived orbits about the oblate Earth. The orbit energy gain due to asymmetric solar radiation pressure, considering the Earth's shadow, is used to balance the energy loss due to atmospheric drag. Future missions for a swarm of SpaceChips are proposed, where a number of small devices are released from a conventional spacecraft to perform spatially distributed measurements of the conditions in the ionosphere and exosphere. It is shown that the orbit lifetime can be extended and indeed selected through solar radiation pressure and the end-of-life re-entry of the swarm can be ensured, by exploiting atmospheric drag
Public Policy in a Private Arena: The Case of Vocational Education and Training
No full textM.21586-1998 Colin Crouch. 30 cm. This paper is based on a seminar that he presented at the Center for Advanced Study in the Social Sciences of the Juan March Institute, Madrid, on 9 May 1995, entitled Diversity in Modern Capitalism: Examples from Vocational Education." -- T.p. Includes bibliographical references (p. 35-37
Oregon statewide status and trends report
No full textReport -- Appendix A. Black Rock Desert-Humboldt -- Appendix B. Columbia River -- Appendix C. Deschutes -- Appendix D. Goose Lake -- Appendix E. Grande Ronde -- Appendix F. John Day -- Appendix G. Klamath -- Appendix H. Malheur -- Appendix I. Mid Coast -- Appendix J. Middle-Columbia-Hood -- Appendix K. North Coast-Lower Columbia -- Appendix L. Oregon Closed Basins -- Appendix M. Owyhee -- Appendix N. Powder-Burnt -- Appendix O. Rogue -- Appendix P. Sandy -- Appendix Q. Snake River -- Appendix R. South Coast -- Appendix S. Umatilla-Walla Walla-Willow -- Appendix T. Umpqua -- Appendix U. Willamette.prepared by: Colin Donald and Ryan Michie.Title from PDF cover (viewed on November 4, 2022).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
The productivity effects of decentralized reforms - an analysis of the Chinese industrial reforms
No full textThe empirical literature on the effects of ownership has not distinguished between the effects of ownership and the effects of control. It has also generally ignored the dynamic effects of various ownership and control rights. Using a rich set of panel data about changes in China's state-owned enterprises, the author examines the static and dynamic effects of decentralizing ownership and control rights. He finds that productivity and growth rates improved significantly when reform improved the incentives for managers and employees to learn and to work hard - for example by decentralizing the rights to control wages, make production decisions, and appoint new managers. Increasing profit-retention rates and adopting performance contracts - conventionally viewed as the most important reforms for China's state enterprises - did not improve productivity much. Overall, decentralization accounted for a least 42 percent of productivity growth in Chinese state enterprises in the 1980s. Much of that gain came from improvements in the growth rate of productivity rather than in improved levels of productivity.Labor Policies,Economic Theory&Research,Environmental Economics&Policies,Banks&Banking Reform,Public Health Promotion,Economic Theory&Research,Environmental Economics&Policies,Banks&Banking Reform,Health Monitoring&Evaluation,Municipal Financial Management
THE STATE OF THE SO RADICAL
No full textAuthor Institution: Laboratoire de Chimie Physique Mol\'{e}culaire, Universit\'{e} Libre de BruxellesThe emission spectrum of the SO radical has been reinvestigated at high resolution from a microwave discharge in using a Bruker FTS 120HR spectrograph. Since , the state has been known to undergo predissociation and to present complex rotational perturbations on the v=1,2 and 3 vibrational levels, but no satisfactory of these features, caused by a state, has been performed. A new attempt which investigated both and isotopomers has led to new information concerning the state and will be presented. FA4(4:08) and FA5(4:25) will be presented here at the request of the author who must return to Japan on E. Martin, Phys. Rev. 41, 167 (1932) D. Abadie, Ann. Phys. 5, 227 (1970)"
Oregon statewide status and trends report
No full textChapter 1-3. Introduction and Methods -- Chapter 4-5. Results and Citations -- Appendix A. Black Rock Desert-Humboldt -- Appendix B. Columbia River -- Appendix C. Deschutes -- Appendix D. Goose Lake -- Appendix E. Grande Ronde -- Appendix F. John Day -- Appendix G. Klamath -- Appendix H. Malheur -- Appendix I. Mid Coast -- Appendix J. Middle-Columbia-Hood -- Appendix K. North Coast-Lower Columbia -- Appendix L. Oregon Closed Basins -- Appendix M. Owyhee -- Appendix N. Powder-Burnt -- Appendix O. Rogue -- Appendix P. Sandy -- Appendix Q. Snake River -- Appendix R. South Coast -- Appendix S. Umatilla-Walla Walla-Willow -- Appendix T. Umpqua -- Appendix U. Willamette.prepared by: Colin Donald, Yuan Grund, and Ryan Michie.Title from PDF cover (viewed on October 27, 2020).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
Oregon statewide status and trends report
No full textReport -- Appendix A. Black Rock Desert-Humboldt -- Appendix B. Columbia River -- Appendix C. Deschutes -- Appendix D. Goose Lake -- Appendix E. Grande Ronde -- Appendix F. John Day -- Appendix G. Klamath -- Appendix H. Malheur -- Appendix I. Mid Coast -- Appendix J. Middle-Columbia-Hood -- Appendix K. North Coast-Lower Columbia -- Appendix L. Oregon Closed Basins -- Appendix M. Black Owyhee -- Appendix N. Powder-Burnt -- Appendix O. Rogue -- Appendix P. Sandy -- Appendix Q. Snake River -- Appendix R. South Coast -- Appendix S. Umatilla-Walla Walla-Willow -- Appendix T. Umpqua -- Appendix U. Willamette.prepared by: Colin Donald, Ryan Michie, and Yuan Grund.Title from PDF cover (viewed on March 20, 2020).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Includes bibliographical references.Mode of access: Internet from the Oregon Government Publications Collection.Text in English
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