3 research outputs found
Benefit of Mandatory Breaks in Nursing
No full textThe evidence-based practice project focused on implementing mandatory breaks that are beneficial for nurses to prevent work fatigue. Research has shown many nurses leaving their jobs within the past five years. This alarming fact demonstrates our need to make pertinent changes to maintain competent nurse employment and promote nurse health and longevity in their career. This presentation discusses how COVID-19, travel nursing, burnout, generational differences, and education are all factors for needing mandatory nurse breaks
Initial experiment of Adaptive Therapy to control Breast Cancer
No full textabstract: Adaptive therapy utilizes competitive interactions between resistant and sensitive cells by keeping some sensitive cells to control tumor burden with the aim of increasing overall survival and time to progression. The use of adaptive therapy to treat breast cancer, ovarian cancer, and pancreatic cancer in preclinical models has shown significant results in controlling tumor growth. The purpose of this thesis is to draft a protocol to study adaptive therapy in a preclinical model of breast cancer on MCF7, estrogen receptor-positive, cells that have evolved resistance to fulvestrant and palbociclib (MCF7 R). In this study, we used two protocols: drug dose adjustment and intermittent therapy. The MCF7 R cell lines were injected into the mammary fat pads of 11-month-old NOD/SCID gamma (NSG) mice (18 mice) which were then treated with gemcitabine.
The results of this experiment did not provide complete information because of the short-term treatments. In addition, we saw an increase in the tumor size of a few of the treated mice, which could be due to the metabolism of the drug at that age, or because of the difference in injection times. Therefore, these adaptive therapy protocols on hormone-refractory breast cancer cell lines will be repeated on young, 6-week old mice by injecting the cell lines at the same time for all mice, which helps the results to be more consistent and accurate. (abstract
PROFESSIONALISM — A PRECONDITION OF OBJECTIVE AND HONEST JOURNALISM
No full textKakvi su današnji masovni mediji? Jesu li dovoljno objektivni ili su potro- šači nezadovoljni? Koliko su aktualna pitanja slobode medija, istinitosti i objektivnosti? Odgovore pokušavamo pružiti upoznavanjem normativne regulative u svijetu i u nas, počevši Kodeksom časti Hrvatskog novinarskog društva, aktima Vijeća Europe i čuvenim Prvim amandmanom na Ustav SAD. Civilno društvo je utemeljilo čitav niz komisija, odbora i vijeća kojima se želi ostvariti utjecaj na masovne medije, kako ne bi bili samo industrija koja zgrće profite, već i ispunjavaju temeljne zahtjeve što se postavljaju pred novinarstvom. Pregledom ostvarivanja sloboda američkog novinarstva vidljivo je da nema gotovog recepta te da se za to treba mukotrpno boriti. Najbolji je način ostvarivanja prava na slobodu izražavanja dosljedno poštivanje standarda profesionalnog novinarstva. No, naša iskustva i praksa govore kako je upravo tu i najviše nedostataka. Posebno je zanimljivo kako su te probleme uočili hrvatski publicisti Frano Folnegović i Bogoslav [ulek prije više od 100 godina. Ne računajući politička ograničenja i utjecaje, hrvatski novinari nedovoljno pažnje polažu upravo na poštivanje standarda profesionalnog novinarstva, što se najbolje može ilustrirati primjerom katastrofe američkog aviona u Dubrovniku, kad su neki mediji objavili ne samo vijest o slijetanju nego tiskali i izjavu već mrtvog američkog ministra. Samo striktnim poštivanjem profesionalnih standarda, što se postiže uz stalno usavršavanje, studiranje i razvijanje znanja, mogu se stvoriti preduvjeti za objektivno i pošteno informiranje.What are today’s mass media like? Are they objective enough or are consumers too fastidious? How topical the issues of the freedom of the media, truth, and objectivity are? The author has tried to provide the answers by looking into the norms and regulations in Croatia and abroad, beginning with the Code of Honour of the Croatian Association of Journalists, the documents of the Council of Europe and the famous First Amendment to the US Constitution. Civil society has set up many commissions, councils and committees with the aim of controlling mass media so that they would not only be a profit-amassing industry but would also conform to the fundamental demands that are put on journalism. A probe into the freedoms of American journalism shows that there are no all-inclusive recipes and that these freedoms must be fought for and won. The best way to secure the right to the freedom of speech is to consistently respect the standards of professional journalism. However, our experience and practice show that this aspect is most lacking. Particularly interesting is how these problems were noticed by Croatian journalists Frano Folnegovi} and Bogoslav [ulek more than a century ago. Apart from the political restrictions and pressures, Croatian journalists do not pay enough attention to this respect for the standards of professional journalism, which can best be illustrated by the example of the catastrophe of that American plane near Dubrovnik, when some media reported not only that the plane had safely landed but published the late Secretary’s statement. Only by strictly respecting professional standards, which may be achieved through constant improvement, study and research, the preconditions for objective and authentic reporting may be realised
