1,721,071 research outputs found

    Erratum to: Is paracetamol better than placebo for knee and hip osteoarthritis? A Cochrane review summary with commentary (International Journal of Rheumatic Diseases, (2020), 23, 4, (595-596), 10.1111/1756-185X.13827)

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    The authors would like to draw the readers' attention to an error in the following article: Negrini F, Negrini S. Is paracetamol better than placebo for knee and hip osteoarthritis? A Cochrane review summary with commentary. Int J Rheum Dis. 2020;23(4):595-596. Affiliation 2 should read as: Department of Biomedical, Surgical and Dental Sciences, University of Milan "La Statale", Milan, Italy. The publisher apologizes for this error and any confusion this may have caused

    Are epidural corticosteroid injections effective for lumbosacral radicular pain? A Cochrane Review summary with commentary

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    Epidural corticosteroid injection is one of the most common non-surgical procedures for lumbosacral radicular pain. OBJECTIVE: To assess efficacy and safety of epidural corticosteroid injections compared with placebo injections in patients with lumbosacral radicular pain. METHODS: A summary and commentary of a Cochrane Review by Oliveira et al. RESULTS: 25 studies with a total of 2740 participants were included in the review. Moderate quality evidence pointed out a small effect on leg pain at immediate and short-term follow-up and on disability at short-term and intermediate follow-up. Adverse events were not different between corticosteroid and placebo injections. CONCLUSIONS: Epidural corticosteroid injection is slightly more effective than placebo for leg pain and disability at short-term follow up. Clinicians and patients however should be informed of the small effect size of the treatment

    In-situ collagen injection in postamputation symptomatic neuroma: A case report

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    Rationale: Postamputation pain remains a significant clinical challenge, affecting a substantial proportion of individuals with limb loss. Among its etiologies, symptomatic neuromas-resulting from aberrant peripheral nerve regeneration-are a common source of residual limb pain. These lesions often lead to severe discomfort and a considerable decline in the quality of life. Although surgical treatments are available, they are often invasive and carry a risk of complications, especially in elderly or frail patients. Nonsurgical interventions, such as steroid injections, provide temporary relief but lack long-term efficacy. Patient concerns: This case study investigates the use of in situ collagen injections as a novel treatment for symptomatic neuroma in an 87-year-old patient with a longstanding transfemoral amputation. The patient had experienced similar symptoms multiple times before, marked by exacerbation and partial remission periods. However, these symptoms have become more intense and disabling over the past 3 months. Diagnoses: A thorough neurological evaluation revealed no overt motor or sensory deficits aside from pain, hypersensitivity, and tenderness above a soft tissue mass on the posteromedial side of the transfemoral stump. Elicitation of Tinel's sign reproduced both phantom and residual limb pain. A diagnosis of symptomatic postamputation neuroma was established based on clinical criteria and further corroborated by ultrasound imaging, which allowed direct visualization of the neuroma. Interventions: The therapeutic protocol involved 2 ultrasound-guided perineuromal injections of a porcine-derived collagen medical device, administered 3 days apart. Pain intensity and sonographic characteristics of the neuroma were assessed over a 12-week follow-up period. Outcomes: Results indicated a significant reduction in pain 1 week after the second injection, with improvements lasting up to 4 weeks. Functional outcomes, including prosthetic tolerance, also showed improvement. However, the treatment's effect diminished by the 12-week follow-up. Lessons: This case highlights the potential utility of in situ collagen injections as a safe, minimally invasive therapeutic option for symptomatic neuromas. Although the observed analgesic and functional benefits warrant further investigation, collagen injections could offer a new therapeutic approach for managing neuroma pain and serve as a promising alternative to more invasive interventions, especially in the elderly and multimorbid patients

    Rehabilitation after knee arthroplasty. An accelerated multidisciplinary approach

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    Fast-track knee arthroplasty is a multidisciplinary perioperative approach resulting in decreased convalescence, better patient satisfaction, and reduced hospital costs. However, considerable room for improvement had been recently identified in the postoperative portion of care. Which prognostic factors, in that phase, can improve the outcomes of rehabilitation, in terms of functional recovery and patient satisfaction, how, and for whom? Surgeons, physiatrists and physiotherapists from our high-volume hospital identified five postoperative issues as significantly prognostic to rehabilitation. An electronic research was performed to look for the associate keywords. 30 papers were included in the synthesis. Clinical, social, psychological and logistical prognostic factors are fundamental to improve patient education and compliance. Intensive and early physiotherapy when possible; standard exercise programs based on patient cluster of characteristics; discharge planning according to functional, psychological and social criteria; patient motivation; use of psychopharmacological treatment; substantial connection between institutions; are postoperative prognostic factors which play a major impact on the effectiveness of rehabilitation after fasttrack TKA. Future research should identify recovery curves to predict, track and understand specific outcomes to specific cohorts of patients, in order to refer them to the most suitable rehabilitative modality and setting

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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