186,556 research outputs found
HOW WILL DEMOGRAPHIC CHANGE AFFECT THE DISEASE BURDEN OF FUTURE EPIDEMICS?
No full texton the cobas SARS-CoV-2 assay (Roche) and the Aptima SARS-CoV-2 assay (Hologic). Findings: We demonstrated comparable sensitivity, specificity, and agreement between self-collected nasal and Rhinoswab samples , compared to HCW-collected samples tested using the cobas SARS-CoV-2 and Aptima SARS-CoV-2 assays. In our study the clinical performance of self-collected specimens was comparable to HCW-collected samples, with both self-collect nasal and Rhi-noswab samples resulting in 90-95% sensitivity, and in most cases > 95% specificity. Discussion: Without the availability of samples for NAAT the ability to perform genomic testing is limited, reducing surveillance and public health investigations. We showed that genomic sequencing from self-collected samples can correctly identify the virus lineage and that the main determination of successful ge-nomic testing is a high viral load rather than collection method. Conclusion: These data support self-collection as an accessible method for community testing for COVID-19 and introduces a novel collection device, the Rhinoswab as an alternative to the standard nasal swab. The testing method of self-collection can be expanded from the widely used RATs to NAAT and genomic testing which may inform the management and public health response to the COVID-19 pandemic
Supplemental Material - A closer look at demand-side explanations for the Matthew effect in formal childcare uptake in Europe and Australia
No full textSupplemental Material for A closer look at demand-side explanations for the Matthew effect in formal childcare uptake in Europe and Australia by Jonas Wood, Karel Neels and Julie Maes in Journal of European Social Policy</p
Author-wise bibliometric analysis based on entropy.
No full textAuthor-wise bibliometric analysis based on entropy.</p
Going Beyond Counting First Authors in Author Co-citation Analysis
No full textThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Appropriate Similarity Measures for Author Cocitation Analysis
No full textWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Postponement and recuperation of Belgian fertility: how are they related to rising female educational attainment?
No full textFertility trends in Europe after 1970 are routinely referred to in terms of the postponement of fertility. The shortening of the effective reproductive lifespan and its association with post-materialist values have raised questions as to whether fertility can or will be recuperated. Decomposition of cohort fertility in Belgium by level of education shows that the postponement of fertility after 1970 is closely related to the expansion of education: compared with cohorts born in 1946-1950, 40 to 50 per cent of the difference in cumulated fertility at age 25 in the 1951-1975 birth cohorts is attributable to rising educational levels. Educational differentials also prove relevant with regard to the recuperation of fertility at older ages as the tempo and quantum of order-specific fertility have responded differently to variations in the economic and policy context, depending on the educational level considered. Differential fertility trends by level of education have thus attenuated the relationship between female educational attainment and completed fertility in recent cohorts.
Dispelling the Myths Behind First-author Citation Counts
No full textWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
Dr. Edward P. Wimberly, ITC, July 2011
No full textThis video is a conversation with Dr. Edward P. Wimberly. Dr. Wimberly talks about his book, "No Shame in Wesley's Gospel: A Twenty-First Century Pastoral Gospel". Brad Ost, AUC Woodruff Library, is the interviewer
Spatial and temporal evaluation of iodine uptake and radiodensity in meniscus tissue using contrast-enhanced micro-CT
No full textRationale and objective: The visualization of soft tissues, like the meniscus, through X-ray micro-computed tomography (micro-CT), requires the use of contrast agents (CAs). While other studies have investigated CA diffusion in fibrocartilagineous tissues, this work aimed to optimize iodine staining protocols for meniscal tissue that improve their visualization by micro-CT. Specific objectives included evaluating the diffusion of CAs within meniscal samples over time, assessing volume changes due to staining, and identifying the iodine ions absorbed by the tissue. Materials and methods: Water-based and PBS-based Lugol solutions (KI3) were used to stain sheep and pig menisci for 24 days. Samples were scanned using micro-CT at different time points (0, 1, 4, 8, 12, 16, 20, and 24 days) to monitor CA diffusion and volume changes. Micro-CT provided three-dimensional (3D) visualization of iodine distribution and quantification of volume changes and radiodensity in the menisci. Additionally, UV–visible spectroscopy (UV–vis) analyses were performed to determine the uptake of iodine ions by the meniscus. Results: Results indicated volumetric shrinkage and increased radiodensity within the first days of staining, with diffusion primarily occurring from the periphery of the meniscus. UV–visible spectroscopy identified two iodide ions in the CA solution (I− and I3−) and revealed a preferential absorption of the triiodide ion (I3−). Conclusion: This study demonstrated the utility of iodine-based CAs and micro-CT technique for visualizing and investigating the spatial and temporal iodine diffusion within the meniscal tissue of sheep and pigs. The findings of this study have important implications for using iodine-based CAs in imaging analyses of the meniscus and offer potentially valuable insights into the diffusion patterns of iodine in fibrocartilagineous tissues
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