28 research outputs found
Configuration of wireless connectivity and spatial boundaries for IoT monitoring devices
No full textThis electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Thesis: M. Eng., Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Science, 2019Cataloged from student-submitted PDF version of thesis.Includes bibliographical references (page 67).A common challenge shared by IoT (Internet of Things) devices is to provide a reliable, user-friendly, and scalable configuration system. In this thesis we examine the configuration of WiTrack, a wall-mounted IoT device that provides real-time health monitoring using RF signals. WiTrack requires configuration of two primary components: its wireless connectivity and the boundaries of spaces it collects data from. The present configuration procedure for WiTrack does not function in all deployment environments, requires expert knowledge, and does not scale well. This thesis introduces the first configuration system for WiTrack, comprised of two subsystems: ConnectivityManager and SpaceManager. ConnectivityManager enables configuration of WiTrack's wireless connection, and SpaceManager allows configuration of spatial boundaries by tracking an individual's movement throughout a space. We evaluated both systems through a user study consisting of eight participants in six unique homes. We found that ConnectivityManager successfully allows configuration of all network security types, and SpaceManager produces boundaries that are accurate within 0.5 meters. The full deployment process can be completed within 15 minutes, and the systems reduce sources of human error as well as effort required for deployment. Compared to the previous configuration process, ConnectivityManager and SpaceManager represent a significant improvement in functionality, time, and usability for WiTrack deployments.by Zareen Choudhury.M. Eng.M.Eng. Massachusetts Institute of Technology, Department of Electrical Engineering and Computer Scienc
DATASET ABA INSENSITIVE 2 promotes flowering by inhibiting OST1/ABI5-dependent FLOWERING LOCUS C transcription in Arabidopsis
No full textFile List: Supplemental Figures 1-7. Supplemental Table 1.The plant hormone abscisic acid (ABA) is an important regulator of plant growth and development and plays a crucial role in both biotic and abiotic stress responses. ABA modulates flowering time, but the precise molecular mechanism remains poorly understood. Here we report that ABA INSENSITIVE 2 (ABI2) is the only phosphatase from the ABA-signaling core that positively regulates the transition to flowering in Arabidopsis. Loss-of-function abi2-2 mutant shows significantly delayed flowering both under long day and short day conditions. Expression of floral repressor genes such as FLOWERING LOCUS C (FLC) and CYCLING DOF FACTOR 1 (CDF1) was significantly up-regulated in abi2-2 plants while expression of the flowering promoting genes FLOWERING LOCUS T (FT) and SUPPRESSOR OF OVEREXPRESSION OF CONSTANS 1 (SOC1) was down-regulated. Through genetic interactions we further found that ost1-3 and abi5-1 mutations are epistatic to abi2-2, as both of them individually rescued the late flowering phenotype of abi2-2. Interestingly, phosphorylation and protein stability of ABA INSENSITIVE 5 (ABI5) were enhanced in abi2-2 plants suggesting that ABI2 dephosphorylates ABI5, thereby reducing protein stability and the capacity to induce FLC expression. Our findings uncovered the unexpected role of ABI2 in promoting flowering by inhibiting ABI5-mediated FLC expression in Arabidopsis. © 2024 The Author(s).Supported by grants from the National Research Foundation of Korea (NRF) funded by the Korean Government (2022R1A2C3004098 to DJY and RS-2023-00239735 to JP), and Bulgarian National Science Fund (project CAFTA, Grant No. КП06 ДВ/2 ЦС to AA and TG).Peer reviewe
اردو نعت کے جدید رجحانات: تحقیقی جائزہ بحوالہ خصوصی شوکت زرّین چغتائی
No full textUrdu Naat kay Jadeed Rujhanaat (Research Analysis of Urdu Naat) by Dr. Shaukat Zareen Chugtai is a research thesis of Ph.D. by the author. In this article, the author has written about different subject matters used in Naats, such as philosophy, history and the ones in the light of Quran and Hadiths. The groundwork also includes references of different contributors to Urdu Naat. Thus this research has attained an important place in Urdu Literature. This analysis will be special guidance to all the future researchers in the field of Urdu Naat. This article is a brief discussion on the research analysis of Dr. Shaukat
Design and analysis of non-uniform MIMO array for interference suppression and automotive applications
No full textAutomotive radars play a very important role in reduction of traffic accidents and casualties by making the vehicle fully self aware of its surroundings. For the vehicle to be fully self aware multiple sensors or radars have to placed in close proximity of each other on the body of the automobile. This will lead to interference between the radars which results in sub optimal performance of the radar system. Currently most of interference mitigation techniques employ various methods of signal coding algorithms, by assigning each radar a different code or modifying beamforming and angle of arrival algorithms to suppress the interference. Most of theses technique use and exploit the properties of the transmitted signal (signal processing techniques) for mitigating the interference. In this thesis the avenue of antenna array design for mitigation of interference is explored. By modifying the radiation pattern of the array, the antenna array will act as spatial filter against the incoming interference signals. In this thesis two techniques for designing the antenna array with improved radiation pattern are proposed. The design techniques are used to optimize the MIMO virtual array of the radar for low sidelobes and increased aperture, and the optimized virtual array is then factorized to obtain the Tx and Rx arrays. 2 virtual arrays of 12 elements and 24 elements are optimized using the design techniques. The performance of the various designs is ranked based on the output SINR of an adaptive beamformer. The simulations results show that the optimized MIMO arrays result in an improvement of up to 3.5dB in SINR in comparison to the currently used topologies. Finally, a prototype of the improved MIMO antenna system is modeled in CST MS design environment, and the superior performance of the designed array topologies over the existing array topologies is verified.Microwave Sensing, Signals and SystemsElectrical Engineering | Microelectronic
Accuracy of high resolution computed tomography in pre-operative acquired cholesteatoma
No full textObjective: To determine the accuracy of high resolution computed tomography (HRCT) for diagnosis of acquired cholesteatoma using histopathological finding as gold standard. Materials and Methods: This cross section study of 61 patients, males and females with ages between 10- 35 years was carried out in the department of radiology, Dr Ziauddin Hospital Karachi, from November 2008 to April 2009. Patients clinically diagnosed as having cholesteotoma were referred for scanning. They were selected according to inclusion criteria. Patients were scanned using HRCT technique. Non dependent soft tissue density attenuation mass associated bony erosion in the middle ear/external ear was considered as radiological positive case of cholesteatoma while dependent soft tissue attenuation mass without bony erosion was considered radiologically negative case for Cholesteatoma. Keratinized stratified squamous epithelium with keratin debris and an underline sub-epithelial fibro connective tissue associated bone resorption in it were considered histopathologically positive case for cholesteatoma and without bony resorption were considered negative. Results: Out of 61 patients of clinically diagnosed acquired cholesteatoma 37(60.7%) were males and 24(39.3%) were females. 34(55.5%) patients showed right sided and 27(44.2%) left side temporal bone involvement. Mean age of patients was 22.93 years (SD±8.29). Sensitivity of HRCT technique was 96.4 %, specificity of 80%, positive predictive value of 98.18% and negative predictive value of 67 %. Conclusion: High resolution computed tomography (HRCT) technique is found to have accuracy for diagnosis of pre-operative acquired cholesteatoma using histopathological finding as gold standard
Pedagogy of Care: Emerging from The Crisis
No full textThis paper proposes to embed structured social, emotional, and professional learning tutorials in one of the core-courses that this author teaches to international students enrolled in the Master of Medical Biotechnology (MMB) program offered by the Department of Chemistry and Biochemistry at the University of Windsor. The broad overarching goals are to offer emotion regulation, stress management, resilience, and work-life balance strategies for international students to feel greater autonomy in their lives, in mitigating pandemic-related anxiety, and a sense of ownership in the Canadian economy. New, emerging trends, structural changes, and circumstances redefine how institutions should be organized tomorrow to become the nexus of a new educational model emerging from the crisis and built for the next normal
THE ROLE OF PAROXETINE IN POSTMENOPAUSAL HOT-FLASHES FREQUENCY REDUCTION
No full textBackground:
To evaluate the effects and safety profile of Paroxetine on hot - flashes in post - menopausal women.
Methods:
It was prospective open label control clinical trial. This study is conducted in the Department of pharmacology & Therapeutics in collaboration with the Department of Obstetrics & Gynecology JPMC. The patients were selected from outpatients department (OPD) of Obstetrics & Gynecology. Duration of the study was 12 month from January 2014 to January 2015. Enrolling 180 outpatients who had menopause with hot flushes divided into three groups. The Greene Climacteric Score Scaling was applied to observe the effects of 12.5mg, 20mg Paroxetine on frequency of hot flashes as compared to Placebo.
Results:
Mean GCS scoring frequency in 12.5mg Paroxetine group at 12 week was 1.97±0.31 and the baseline 2.64±0.29. In 20mg Paroxetine mean GCS at baseline was 2.76±0.23 and 12 week 2.04±0.12. Where as in Placebo mean GCS scoring frequency at 12 week was 2.80±0.24 and at baseline 2.76±0.24.Conclusion: The frequency of hot flashes with Paroxetine 20mg and 12.5mg, is significantly reduced in post menopauseal women as compared to Placebo
THE ROLE OF PAROXETINE IN POSTMENOPAUSAL HOT-FLASHES FREQUENCY REDUCTION
No full textBackground:
To evaluate the effects and safety profile of Paroxetine on hot - flashes in post - menopausal women.
Methods:
It was prospective open label control clinical trial. This study is conducted in the Department of pharmacology & Therapeutics in collaboration with the Department of Obstetrics & Gynecology JPMC. The patients were selected from outpatients department (OPD) of Obstetrics & Gynecology. Duration of the study was 12 month from January 2014 to January 2015. Enrolling 180 outpatients who had menopause with hot flushes divided into three groups. The Greene Climacteric Score Scaling was applied to observe the effects of 12.5mg, 20mg Paroxetine on frequency of hot flashes as compared to Placebo.
Results:
Mean GCS scoring frequency in 12.5mg Paroxetine group at 12 week was 1.97±0.31 and the baseline 2.64±0.29. In 20mg Paroxetine mean GCS at baseline was 2.76±0.23 and 12 week 2.04±0.12. Where as in Placebo mean GCS scoring frequency at 12 week was 2.80±0.24 and at baseline 2.76±0.24.
Conclusion: The frequency of hot flashes with Paroxetine 20mg and 12.5mg, is significantly reduced in post menopauseal women as compared to Placebo
Association Between Malnutr ition & Colostrum For Severe Pneumonia
No full textBackground:
Pneumonia remains one of the main causes of childhood mortality despite the availability of simple, safe, effective and inexpensive interventions to curb its mortality. This could result from sub-optimal care seeking practices and child rearing, supplemented by lack of access to healthcare.We conducted a studyto identify the association of malnutrition and initiation of breastfeeding variables with severe pneumonia and pneumonia/no pneumonia
Objective:
To determine association of malnutrition and colostrums intake among children aged 2-24 months admitted in tertiary care hospital for severe pneumonia.
Methods:
A total of 288 patients with severe pneumonia were included in this case-control study. Patients were divided into 2 groups with 144 patients in each group selected through non-probability consecutive sampling. Sample size was calculated using WHO sample size calculator keeping power of test at 80%, P1= 1% and P2=7.8%. Data was analyzed through SPSS version 19 and p-value < 0.05 considered as significant. Association between study variables and severe pneumonia was computed using Chi Square Test.
Results:
Mean age for group A (67 males and 77 females) was 13.00±6.40 months and group B (78 males, 66 females) 12.83±6.90 months. Malnutrition was seen in 41% of group A and 17.4% of group B patients. Colostrum intake (Initiation of breast feeding with 72 hours) was reported in 78.5% of group A and 79.2% of group B. There was a significant association of malnutrition with severe pneumonia (p=0.000) whereas, no significant relation was found with colostrum intake (p=0.885).
Conclusion:
Malnutrition was significantly associated with severe pneumonia. Colostrum was the most prevalent factor in both groups but the difference was insignificant
Association Between Malnutr ition & Colostrum For Severe Pneumonia
No full textBackground:
Pneumonia remains one of the main causes of childhood mortality despite the availability of simple, safe, effective and inexpensive interventions to curb its mortality. This could result from sub-optimal care seeking practices and child rearing, supplemented by lack of access to healthcare.We conducted a studyto identify the association of malnutrition and initiation of breastfeeding variables with severe pneumonia and pneumonia/no pneumonia
Objective:
To determine association of malnutrition and colostrums intake among children aged 2-24 months admitted in tertiary care hospital for severe pneumonia.
Methods:
A total of 288 patients with severe pneumonia were included in this case-control study. Patients were divided into 2 groups with 144 patients in each group selected through non-probability consecutive sampling. Sample size was calculated using WHO sample size calculator keeping power of test at 80%, P1= 1% and P2=7.8%. Data was analyzed through SPSS version 19 and p-value < 0.05 considered as significant. Association between study variables and severe pneumonia was computed using Chi Square Test.
Results:
Mean age for group A (67 males and 77 females) was 13.00±6.40 months and group B (78 males, 66 females) 12.83±6.90 months. Malnutrition was seen in 41% of group A and 17.4% of group B patients. Colostrum intake (Initiation of breast feeding with 72 hours) was reported in 78.5% of group A and 79.2% of group B. There was a significant association of malnutrition with severe pneumonia (p=0.000) whereas, no significant relation was found with colostrum intake (p=0.885).
Conclusion:
Malnutrition was significantly associated with severe pneumonia. Colostrum was the most prevalent factor in both groups but the difference was insignificant
