1,720,970 research outputs found
Prevalence of Balantidium coli (Malmsten, 1857) infection in swine reared in South Italy: A widespread neglected zoonosis
No full textBackground and Aim: Balantidiasis, caused by Balantidium coli (syn. Neobalantidium coli or B. coli), represents a neglected parasitic infection of zoonotic significance affecting a variety of hosts, including domestic pigs that are the main reservoir. B. coli has a direct life cycle with a fecal-oral route transmission that occurs mainly by the ingestion of food and water contaminated with cysts. The ingestion of meat contaminated during inappropriate slaughtering processes may represent a new potential route of transmission. Only a few studies have investigated the prevalence of B. coli in domestic pigs in Italy, despite its high prevalence and zoonotic significance. This study aimed to improve the knowledge on B. coli prevalence in domestic swine reared both in intensive and "en plein air" breeding systems in the south of Italy. Materials and Methods: The infection rate of B. coli in pigs bred in 15 different pig farms and regularly slaughtered in South Italy, in the Calabria region, was investigated. From 2017 to 2019, 177 terminal parts of the rectums of pigs, of which 91 commercial hybrids and 86 autochthonous (Nero Calabrese), reared, respectively, in intensive and "en plein air" breeding system, were tested for parasite detection. After the slaughtering, the terminal part of the rectum was sampled and transported to the laboratories and immediately processed. For the detection of trophozoites, fresh smears of feces were examined at light microscopy. Moreover, flotation was performed using a sodium chloride solution, then smears of feces were dispersed on microscope slides and examined at light microscopy. The observed parasites were identified at the species level using morphological characteristics. Results: B. coli was detected in a total of 83 (i.e., 46.89%) pigs, with a significantly higher prevalence (p<0.0001) found in commercial hybrid (i.e., 59/91-64.84%) pigs rather than in autochthonous ones (i.e., 24/86-27.91%). It follows that the infection was more common in pigs reared in the intensive breeding system than in "en plein air" ones (p<0.0001). The infection prevalence was higher in males than in females and lower in elder animals than in younger ones (p=0.012 and p<0.0001, respectively). Conclusion: The breeding system is likely the main discriminant for the parasite spread as well as the hygienic condition of the farms. Good manufacturing and hygiene practices along the food production chain are crucial in preventing human balantidiasis transmission by meat consumption. The high B. coli prevalence, the wide spectrum of host species, and its zoonotic significance push toward a greater public interest
STRUCTURAL ANALYSIS OF A POSTERIOR STABILITY TOTAL KNEE JOINT REPLACEMENT
No full textAim of this work is to compare two different total knee prostheses that differ in the shape of the Polyethylene (PE) insert, trying to optimize the shape of the best one, in order to reduce the stress peaks.
The study procedure has been divided into the following steps. First step has been the three-dimensional shape acquisition of the two prostheses by means of a COMET5 3D scanner. The morphology of two prototypes of the prostheses has been acquired by elaborating multiple Moirè fringe pattern projected on their surfaces. Second step consisted of the manipulation of these data in a CAD module, that is the interpolation of raw data into parametric surfaces, reducing singularities due to the typical scattering of the acquiring system. Third step has been the setting up of FEM simulations to evaluate the prostheses behaviour under typical loading conditions. The CAD model of the prostheses has been meshed into solid finite elements.
Different flexion angles configurations have been analysed, the load being applied along the femoral axis. FEM analyses have returned stress fields in the PE insert and, in particular, in the stabilizing cam which function is to avoid dislocation.
Last step has been the integrated use of CAD-FEM to modify the shape of the stabilizing cam of the best prosthesis, in order to reduce the stress peaks in the original prosthesis without compromising the kinematics of the joint. Good results have been obtained both in terms of stress and contact pressure peaks reduction
Finite element analysis of two total knee joint prostheses
No full textAim of this work is to compare two different total knee prostheses that differ mainly in the shape of the polyethylene (PE) component inserted between the femoral and tibial plates. The best solution between them has been originally reshaped in order to reduce stress peaks. The study procedure has been divided into the following steps. First step is the digitalisation of the shape of the prostheses by means of a 3D laser scanner. The morphology of two prototypes of the prostheses has been acquired by elaborating multiple Moire fringe patterns projected on their surfaces. Second step consisted on the manipulation of these data in a CAD module, that is the interpolation of raw data into NURBS surfaces, reducing singularities due to the typical scattering of the acquiring system. Third step has been the setting up of FEM simulations to evaluate the prostheses behaviour under benchmark loading conditions given in literature. The CAD model of the prostheses has been meshed into solid finite elements. Different flexion angles configurations have been analysed, the load being applied along the femoral axis. FEM analyses have returned stress fields in the PE insert and, in particular, in the stabilizing cam which function is to avoid dislocation. Last step has been the integrated use of CAD and FEM to modify the shape of the stabilizing cam of the best prosthesis, in order to reduce the stress peaks in the original prosthesis without affecting kinematics of the joint. Good results have been obtained both in terms of stress and contact pressure peaks reductio
Complex pluri-fragmentary fractures of the distal humerus: our experience with double-plate
No full textShoulder replacement in the treatment of pluri-fragmentary and displaced fractures of the proximal humerus: our experience
No full textA new method to evaluate the influence of the glenosphere positioning on stability and range of motion of a reverse shoulder prosthesis
No full textShoulder instability and reduced range of motion are two common complications of a total reverse shoulder arthroplasty. In this work, a new approach is proposed to estimate how the glenoid component positioning can influence the stability and the range of motion of a reverse shoulder prosthesis
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Microsurgery and external fixation in orthoplastic reconstruction of tibial injuries
Full text linkBackground Orthoplastics is a relatively new approach to lower limb reconstruction, where an integration of both plastic and orthopedic expertise is required, together with the availability of well-equipped facilities. Acute shortening and long-term frames for lengthening are generally considered alternatives to length preservation and soft tissue microsurgical reconstruction, but an integration of external fixation and reconstructive microsurgery is gaining an increasing role with refinements of joint approaches. Material and methods Data on sixteen patients who underwent microsurgical lower limb reconstruction and external fixation with an orthoplastic approach, following acute or chronic tibial injury, were retrospectively reviewed. All patients presented a post traumatic soft tissue defect associated with a Gustilo III tibial fracture or a tibial septic pseudarthrosis. Data on type and timing of bone and soft tissue reconstruction, outcomes, complications and need for re-operation were extrapolated and compared to an historic group of patients treated with an orthopedic-based approach. Results In the orthoplastic group, soft tissues were reconstructed with an ALT flap in most cases; a muscle-sparing VL or ALT-VL chimeric flap was necessary in cases with a very extensive defect. In the orthopedic group, soft tissues were left to heal by second intention or patients were lately referred to plastic surgeons. Statistical comparison between the two groups has showed significant differences on the following data: Time for soft tissue healing, time to bone union, number of reinterventions, post-operative deep infection rate, time to return to work. Conclusion The orthoplastic approach to complex leg defects yields shorter treatment time and better functional results compared to the orthopedic-based approach. External fixation and microsurgical reconstruction are not necessarily alternative procedures but can integrate in an orthoplastic path to address at best both soft tissue and bone reconstruction
Influence of the metaphysis positioning in a new reverse shoulder prosthesis
No full textAim of this work is to investigate the behaviour of a new reverse shoulder prosthesis, characterized by a humeral metaphysis with a variable offset, designed to increase the range of movements and to reduce the impingement. In particular, by means of virtual prototypes of the prosthesis, different offset values of the humeral metaphysis have been analysed in order to find the best positioning able to maximize the range of movements of the shoulder joint. The abduction force of the deltoid, at different offset values, has been also estimated. The study has been organized as follows. In the first step, the point clouds of the surfaces of the different components of the prosthesis have been acquired by a 3D scanner. This kind of scanner allows to convert camera images into three-dimensional models by analysing the moiré fringes. In the second step, the acquired point clouds have been post-processed and converted into CAD models. In the third step, all the 3D reconstructed models have been imported and assembled through a CAD system. After, a collision analysis has been performed to detect the maximum angular positions of the arm at different metaphysis offset values. In the last step, FEM models of shoulder joint with the new prosthesis have been created. Different analyses have been performed to estimate how the deltoid abduction force varies depending on the offset of the humeral tray. The study allowed to understand how the offset of the metaphysis affects the performances of the shoulder. The obtained results can be effectively used to give surgeons useful guidelines for the installation of these kinds of implants
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