1,720,960 research outputs found
A systematic review on the detection of carbapenemase-producing Enterobacteriaceae
Full text linkIntroduction: Carbapenemase-producing Enterobacteriaceae (CPE) represents one of the most pressing and critical public health challenges associated with antibiotic resistance. Challenges persist in accurately and promptly identifying CPE despite the existence of diverse carbapenemases and multiple detection methods.
Aim: This study investigated diagnostic methods used for the detection of CPEs.
Methods: The systematic review and meta-analysis were conducted based on Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Electronic databases like Google Scholar, PubMed, Scopus, and Web of Science were used to find relevant articles. In addition, the Joanna Briggs Institute quality appraisal tool was used to assess the quality of the included studies. STATA 14.0 was used for statistical analysis. Heterogeneity was assessed by using Cochran’s Q test and 12 statistics. In addition, publication bias was assessed using a funnel plot and Egger’s test. A random effect model was used to estimate the pooled prevalence.
Results: The meta-analysis revealed an overall pooled proportion of 40.53% for phenotypic detection of carbapenemase activity across the 11 studies, with substantial heterogeneity observed. Subgroup analysis highlighted variations in detection proportions based on different methods, with mCIM showing the highest proportion at 58,20%, Carba NP at 27.79%, and MHT at 34,62%. Evaluation of publication bias indicated little impact on the results, maintaining the stability of the meta-analysis outcomes.
Conclusion: In conclusion, this systematic review showed a high prevalence of CPE across the studies. This study emphasizes the importance of standardized detection methods, global collaboration, and the integration of advanced techniques for accurate CPE detection
Iron binding compounds produced by novel actinomycetes
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The Use of Proteolytic Activity to Evaluate Meat Tenderising Agents
No full textTenderness is considered to be the most important meat characteristic. Currently common methods of evaluating meat tenderisation include scanning calorimetry, texture profile analysis and WBSF measurements. Here we report the use of a scientific tool based upon a colourimetric protease assay to screen natural products as tenderising agents.Read Complete Article at ijSciences: V220131235
Going Beyond Counting First Authors in Author Co-citation Analysis
Full text linkThe present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
Full text link“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Acne vulgaris: the skin microbiome, antibiotics and whether natural products could be considered a suitable alternative treatment?
Full text linkAcne vulgaris is a common, chronic inflammatory skin disease manifested as inflammatory and non-inflammatory lesions typically associated with Cutibacterium acnes. However, its pathogenesis is not fully understood nor is the complexity of the skin microbiome and how it contributes to the development of acne. Whilst acne is not a typical bacterial infection, antibiotics have been the mainstay of treatment for over 50 years. Now, with the development of multi-drug resistant organisms and the emergence of resistant C. acnes strains; the question is are antibiotics still an appropriate treatment method or could natural products provide a suitable alternative? Research into alternative treatments is a growing field due to the increase in resistant organisms, there is a multitude of research into natural products due to their antimicrobial potential and the multiple mechanisms of action. Melaleuca alternifolia is a key natural product of interest in the treatment of acne due to its documented use throughout history and its prevalence in over the counter treatments. Green Tea is a more recent natural product of interest due to its composition of polyphenols, which give rise to both antimicrobial and anti-inflammatory properties. However, research also suggests that a synergistic approach of natural products may be the way forward
Appropriate Similarity Measures for Author Cocitation Analysis
Full text linkWe provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis
Dispelling the Myths Behind First-author Citation Counts
Full text linkWe conducted a full-scale evaluative citation analysis study of scholars in the XML research field to explore just how different from each other author rankings resulting from different citation counting methods actually are, and to demonstrate the capability of emerging data and tools on the Web in supporting more realistic citation counting methods. Our results contest some common arguments for the continued
use of first-author citation counts in the evaluation of scholars, such as high correlations between author rankings by first-author citation counts and other citation
counting methods, and high costs of using more realistic citation counting methods that are not well-supported by the ISI databases. It is argued that increasingly available digital full text research papers make it possible for citation analysis studies to go beyond what the ISI databases have directly supported and to employ more
sophisticated methods
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