99,797 research outputs found

    Joshua Davis: Author of Spare Parts

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    Citation: K-State First (2016). Joshua Davis: Author of Spare Parts [Flier]. Manhattan, Kansas: K-State First.Flyer advertising Joshua Davis's author talk at Kansas State University

    Treating TB patients' mental health

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    Treating depression and increasing the quality of social support should improve the overall management of TB infection and raise the cure rate, write PAMELA NAIDOO and KELVIN MWABA.

    Steven Johnson Author Talk Poster

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    K-State Book NetworkA poster advertising an author talk by Steven Johnson at Kansas State University on September 3, 2014. Steven Johnson's book "The Ghost Map" was the 2014-2015 common book

    Treating TB patients' mental health

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    Treating depression and increasing the quality of social support should improve the overall management of TB infection and raise the cure rate, write PAMELA NAIDOO and KELVIN MWABA.

    The effects of petroleum hydrocarbon contamination on selected intertidal macrophytes and meiofauna.

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    Doctor of Philosophy in Biology. University of KwaZulu-Natal, Durban 2015.The effects of bunker fuel oil on the growth of A. marina, B. gymnorrhiza and R. mucronata were investigated in glasshouse and field experiments. The effects of oil on community structure in micro-organisms were also investigated in microcosm glasshouse experiments. The differences in oil tolerance of the three mangroves were compared in propagule and sediment oiled treatments and growth monitored for 13 months under glasshouse conditions. In propagule oiled treatments, various portions of the propagule were coated with oil. In the sediment oiled treatments, 50ml oil were added to the sediment in each pot. In oiled treatments, plant height, number of leaves and chlorophyll content were significantly reduced in all species compared to the control. In A. marina and R. mucronata, oiling resulted in growth malformations such as abnormal phyllotaxy and deformity of leaves and stems. The effects of oil on root growth were investigated in rhizotrons for 245 and 409 days respectively. In oiled treatments, root growth rate, length and volume were significantly reduced in all species. In A. marina and B. gymnorrhiza oil increased root diameter. In another series of experiments, PAH accumulation in roots and leaves of the three species were determined in one year old seedlings subjected to oiling for 21 days. The concentrations of 15 PAHs in roots and leaves were determined by gas chromatography / mass spectrometry. The highest total concentration of PAHs was accumulated in oiled roots of A. marina (44,045.9μg/kg), followed by B. gymnorrhiza (10,280.4μg/kg) and R. mucronata (6,979.1μg/kg). In oiled treatments, the most common PAHs in roots of all species were fluorene and acenaphthene (two rings), phenanthrene and anthracene (three rings), pyrene and chrysene (four rings) and benzo[a]pyrene (five rings). In the leaves of all species in oiled treatments, the common PAHs were naphthalene and acenapthene (two rings) and phenanthrene (three rings). To test for living and dead root tip cells and to compare the effects of oil on cell ultrastructure in roots and leaves of the three species, one year old seedlings were subjected to a control and sediment oiled treatments for seven days. Control root tips, stained with fluorescein diacetate, exhibited green fluorescence in living cells of the meristematic and conducting tissue in all species. Oiled root tips, stained with propidium iodide, exhibited red fluorescence, indicating cell death or dead cells. Transmission electron micrographs revealed that oil damaged cell ultrastructure in root tips and leaves in all species. Anatomical changes induced by oil included, disorganization of cells in the root cap, epidermis and meristem. Oil also induced loss of cell contents and destruction of organelles in root tissue. Oil damaged chloroplasts and cell organelles in spongy mesophyll and palisade cells of leaves. To compare the effects of oil on the ability of the three species to tolerate salinity, healthy one year old seedlings were subjected to 10% and 50% seawater in control and sediment oiled treatments for 12 months. In the oiled treatments, 200ml oil were added to the soil in each pot. Oil significantly reduced growth in the 50% seawater treatment in all species. Results suggested that oil reduces salt tolerance in the three species. The effects of oil on salt secretion in A. marina were investigated by subjecting one year old seedlings to sediment oiling treatments at 0%, 10% and 50% seawater for three weeks. Sodium accumulated in the leaves of oiled seedlings at 10% and 50% seawater. The effects of oil on salt secretion in A. marina in the light and dark were compared in one year old seedlings subjected to oiling treatments for seven days. Sodium accumulated in the leaves of oiled seedlings in the light and dark within 11 hours. Oil reduced secretion rates of Na⁺, K⁺, Ca²⁺ and Mg²⁺ in all treatments. The effects of oil on species abundance, richness and community structure of soil micro-organisms were determined by subjecting microcosms to oiling treatments with or without fertiliser for four weeks. In the oiled treatments, 15ml oil and 5ml/L fertiliser were added to 200g soil. Fertiliser consisted of 4% N, 2% P and 5% K. Nematodes were extracted after the experimental period and identified to genus or species level. Oil significantly reduced species abundance and richness. Oil also eliminated sensitive species and altered the abundance of dominant species thereby altering the free living nematode community structure. Addition of fertiliser increased richness and dominant species in oiled treatments. The effects of oil coating on leaves and internodes on growth of the three mangroves were investigated in field experiments for 48 weeks. Oiling of the leaves resulted in leaf abscission and decreased leaf production in all species. The effects of sediment oiling (at a dose of 5Lmˉ²) on the three species were also investigated in a field study for 53 weeks. In A. marina, oil caused adventitious roots to develop on the stem, about 10-15 cm above the soil surface after 38 weeks of treatment. In oiled treatments, plant mortality occurred after 53 weeks in all three species. The ability of B. gymnorrhiza and R. mucronata to exclude PAHs from sensitive root tissues probably accounted for the higher oil tolerance than A. marina. The capacity of the species to adapt to residual oil contamination by increasing root diameter (A. marina and B. gymnorrhiza), producing adventitious roots (A. marina), increasing root/shoot ratio (R. mucronata) and abscising oiled leaves (all species) probably contributed to oil tolerance

    Hyperbilirubinemia in atazanavir-treated human immunodeficiency virus-infected patients: the impact of the UGT1A1*28 allele

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    Anushka Naidoo,1 Kogieleum Naidoo,1,2 Veron Ramsuran,3 Millidhashni Reddy,1 Nesri Padayatchi1,2 1Centre for the AIDS Programme of Research in South Africa, 2MRC-CAPRISA HIV-TB Pathogenesis and Treatment Research Unit, Doris Duke Medical Research Institute, 3School of Laboratory Medicine and Medical Sciences, University of KwaZulu-Natal, Durban, South Africa Panagopoulos et al1 reviewed the effects of the UGT1A1*28 polymorphism on Reyataz® (atazanavir)-related hyperbilirubinemia in human immunodeficiency virus (HIV)-infected patients that may result in increased severity and drug discontinuation in some patients. The effects of the UGT1A1 polymorphisms on the pharmacokinetics of other antiretroviral drugs such as Isentress® (raltegravir) and Edurant® (rilpivirine) are also discussed. We respond here on the relevance of the study findings in the South African context.  View the original paper by Panagopoulos and colleagues.&nbsp

    Going Beyond Counting First Authors in Author Co-citation Analysis

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    The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed

    Appropriate Similarity Measures for Author Cocitation Analysis

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    We provide a number of new insights into the methodological discussion about author cocitation analysis. We first argue that the use of the Pearson correlation for measuring the similarity between authors’ cocitation profiles is not very satisfactory. We then discuss what kind of similarity measures may be used as an alternative to the Pearson correlation. We consider three similarity measures in particular. One is the well-known cosine. The other two similarity measures have not been used before in the bibliometric literature. Finally, we show by means of an example that our findings have a high practical relevance.information science;Pearson correlation;cosine;similarity measure;author cocitation analysis

    Expanding “Communities and Collections” in the K-State Research Exchange (K-REx) to benefit the K-State Community and Beyond

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    Kansas State University has used its institutional repository, the K-State Research Exchange (K-REx), to store and share its first year experience program, K-State First, and notably its common reading program, K-State First Book. We have done so with the aim that the accessibility and preservation of these documents ensures program stability, promotes engagement with first year programming, and provides the ability to foster growth,educational opportunities, and community building outside of K-State. Moving away from research concentrated repositories and taking a more holistic approach to scholarship, especially when realizing the pedagogical significance of collaborative campus programming, institutions can showcase, discover, preserve, and grow programs that shape campus communities and engagement. This session will provide an overview of K-REx and spotlight the digital archive of the university’s first year experience program and common reading program, K-State First Book. We will discuss the benefits and challenges to expanding the purview of your repositories. We talkthrough the types of materials we decide to host in our repository and why we share what we do. We will also provide recommendations on new ways to evaluate what belongs in institutional repositories and how this diversity can benefit your program, your institution, the community, and others

    Ready Player One Program Event Poster

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    K-State Book NetworkA poster advertising an author talk by Ernest Cline at Kansas State University on October 10, 2013. Ernest Cline's book "Ready Player One" was selected as the 2013-2014 common book
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