1,720,989 research outputs found
Exploring the microbiota of Vitis vinifera cv. Pinot Noir in two vineyards with different soil management: metagenomic and metaproteomic analysis
Screening of azole resistance in blood culture isolates of Candida sp.: comparison among different diagnostic system vs gold standard methods.
Whole-genome sequencing of Pseudomonas protegens Pf7: a focus on the antibiotic resistance of a potential biofertilizer
Sensitivity of Candida albicans to essential oils: are they an alternative to antifungal agents?
Aims: Candida albicans is an important opportunistic pathogen, responsible for the majority of yeast infections in humans. Essential oils, extracted from aromatic plants, are well-known antimicrobial agents, characterized by a broad spectrum of activities, including antifungal properties. The aim of this work was to assess the sensitivity of 30 different vaginal isolated strains of C. albicans to 12 essential oils, compared to the three main used drugs (clotrimazole, fluconazole and itraconazole).
Methods and results: Thirty strains of C. albicans were isolated from vaginal swab on CHROMagarTM Candida. The agar disc diffusion method was employed to determine the sensitivity to the essential oils. The antifungal activity of the essential oils and antifungal drugs (clotrimazole, itraconazole and fluconazole) were investigated using a microdilution method. Transmission and scanning electron microscopy analyses were performed to get a deep inside on cellular damages. Mint, basil, lavender, tea tree oil, winter savory and oregano essential oils inhibited both the growth and the activity of C. albicans more efficiently than clotrimazole. Damages induced by essential oils at the cellular level were stronger than those caused by clotrimazole.
Conclusions: Candida albicans is more sensitive to different essential oils compared to the main used drugs. Moreover, the essential oil affected mainly the cell wall and the membranes of the yeast.
Significance and impact of the study: The results of this work support the research for new alternatives or complementary therapies against vaginal candidiasis
In vitro activity of twelve essential oils against clinical skin isolates Staphylococcus aureus
Use of biotic elicitors of resistence against Flavescence Dorée on grapevine and innovative methods to detect symptoms
Susceptibilities of Candida albicans and non-albicans strains vaginal isolates to antifungal agents and essential oils
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
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