1,287 research outputs found
Spatial Transcriptomic changes in mouse iWAT with exercise training
No full textThe spatial transcriptomics data deposited herein are included in the manuscript by Nigro P. & Vamvini M., et al., with the title " Exercise Training Remodels Inguinal White Adipose Tissue Through Adaptations in Innervation, Vascularization and the Extracellular Matrix". These data were generated by using inguinal subcutaneous white adipose tissue from wild type and PRDM16AKO C57BL6n male mice with and without exercise training. The spatial transcriptomics data were generated using FPPE samples using the Visium platform from 10x genomics
Exercise Training Remodels Inguinal White Adipose Tissue Through Adaptations in Innervation, Vascularization and the Extracellular Matrix_Raw data
No full textThe deposited data is presented in the manuscript by Nigro P. & Vamvini M., et al., with the title " Exercise Training Remodels Inguinal White Adipose Tissue Through Adaptations in Innervation, Vascularization and the Extracellular Matrix". Visium data in the format of Space Ranger output can be found for each individual section analyzed, which contains raw and filtered count matrices and spatial/image data. Sample metadata contains information for each sample with linked subject information. Seurat objects containing the downstream analyses can be found as well, which for instance contains the spot clustering information presented in the article. Output data from the stereoscope analysis described in the article can be found here as well.These are raw data and script referred to normalized data published with DOI:10.17632/r6v7yktxnt.
Vertebral hemangiomas: common lesions with still many unknown aspects
No full textHistologically VHs are not considered vascular neoplasms, but rather hamartomas or malformation of the microcirculation. Basing on the predominant type of vascular channel they are classified in: capillary, cavernous, arterio-venous and venous malformations. Most of spinal epidural hemangiomas belongs to the cavernous type (1). Numerous terms have been introduced and different classification systems. Unfortunately, none of these has been accepted due to the lack of accepted histological criteria and limited correlation with clinical outcome. Vascular tumours of bone originate from endothelial cells resulting in variable expression of endothelial markers, but none of these markers is useful to discriminate between benign and malignant lesions. Verbeke and Bovée (2) proposed the classification of vascular tumours of bone according to the WHO classification scheme for soft tissue tumours dividing entities into benign, intermediate and malignant category
Majorana/Andreev crossover and the fate of the topological phase transition in inhomogeneous nanowires
No full textMajorana bound states (MBS) and Andreev bound states (ABS) in realistic Majorana nanowires setups have similar experimental signatures which make them hard to distinguishing one from the other. Here, we characterize the continuous Majorana/Andreev crossover interpolating between fully-separated, partially-separated, and fully-overlapping Majorana modes, in terms of global and local topological invariants, fermion parity, quasiparticle densities, Majorana pseudospin and spin polarizations, density overlaps and transition probabilities between opposite Majorana components. We found that in inhomogeneous wires, the transition between fully-overlapping trivial ABS and nontrivial MBS does not necessarily mandate the closing of the bulk gap of quasiparticle excitations, but a simple parity crossing of partially-separated Majorana modes (ps-MM) from trivial to nontrivial regimes. We demonstrate that fully-separated and fully-overlapping Majorana modes correspond to the two limiting cases at the opposite sides of a continuous crossover: the only distinction between the two can be obtained by estimating the degree of separations of the Majorana components. This result does not contradict the bulk-edge correspondence: indeed, the field inhomogeneities driving the Majorana/Andreev crossover have a length scale comparable with the nanowire length, and therefore correspond to a nonlocal perturbation which breaks the topological protection of the MBS
Letter to the editor: Microsurgical decompression for central lumbar spinal stenosis: a single-center observational study
No full textRole of NADPH oxidase in atherosclerosis
No full textReactive oxidant species (ROS) seem to play a key role in the atherosclerotic process via a series of molecular changes that lead to macrophage infiltration in the endothelium and eventually to plaque formation. ROS are also implicated in arterial dysfunction via inactivation of nitric oxide, a potent vasodilator and antiaggregating molecule produced by the endothelium. Owing to the relevance of endothelial dysfunction and vascular inflammation in the process of human atherosclerosis, a lot of effort has been directed towards discovering the ROS-generating pathways implicated in the ROS upregulation. Amongst the enzymatic pathways, NADPH oxidase is the most important enzyme responsible for ROS formation in human vessels. Experimental and clinical studies suggested a role for this enzyme in initiation and progression of atherosclerotic disease. The purpose of this review is to analyze whether the basic and clinical studies are consistent with this hypothesis and to point out if determination of NADPH oxidase is useful in the setting of the atherosclerosis to predict its progression and clinical complications. © 2009 Future Medicine
Surgery in extensive vertebral hemangioma: case report, literature review and a new algorithm proposal
No full textAuthor Correction: Kombucha electronics: electronic circuits on kombucha mats
No full textCorrection to: Scientific Reports, published online 09 June 2023 The original version of this Article contained an error in the spelling of the author Pasquale D’Angelo which was incorrectly given as Passquale D’Angelo. The original Article has been corrected
Spazi pubblici e luoghi condivisi. Progetti architettonici per le città europee
No full textSotto la responsabilità intellettuale e supervisione diretta dell'autore, il volume raccoglie i contributi scritti dai relatori che hanno partecipato al ciclo di conferenze Spazi pubblici e luoghi condivisi. Progetti architettonici per le città europee, ideato da Guya Bertelli e coordinato dal sottoscritto. Il symposium è stato promosso dal Dipartimento di Architettura e Studi Urbani (DAStU) e le conferenze hanno avuto luogo, tra il 2012 e il 2013, presso la sede centrale del Politecnico di Milano e presso il Campus Arata del Polo Territoriale di Piacenza.
Le quattro giornate di studio sono state organizzate in modo tale che il dibattito prendesse in esame, nell’ambito della stessa giornata, una coppia di città europee, rendendo possibile un fertile confronto. I contributi dei relatori - Enric Massip Bosh e Carlos Garcia Vazquez; Hervé Dubois e Gill Novarina; Stefan Vieths e Michele Giovanni Caja; Francisco Arqués Soler e Maria Vittoria
Capitanucci - sono articolati in quattro diversi capitoli. Ciascun capitolo presenta gli interventi della relativa giornata di studio ed è aperto da un’introduzione, e seguito da una conclusione a firma del coordinatore della giornata. I quattro capitoli sono inoltre preceduti da un’introduzione di Gabriele Pasqui e dai saggi di Guya Bertelli, Michele Roda e del sottoscritto che riflettono, attraverso uno sguardo critico, sul ruolo e sul significato dello spazio pubblico nella città contemporanea.Under the intellectual responsibility and direct supervision of the author, the publication collects contributions by the lecturers in the series of conference Public spaces and shared places. Architectural projects for the European cities created by Guya Bertelli and coordinated by Pasquale Mei. The symposium was sponsored by the Department of Architecture and Urban studies (DAStU) and the conferences have been organized in 2012 and 2013 at Politecnico di Milano, Campus Leonardo, and at Arata Campus, in the Territorial Campus of Piacenza. The debates were part of the four working days; each one was dedicated to an interesting comparison between two European cities. The contributions of the lecturers - Enric Massip Bosh and Carlos Garcia Vazquez; Hervé Dubois and Gill Novarina; Stefan Vieths and Michele Giovanni Caja; Arqués Francisco Soler and Maria Vittoria Capitanucci - are divided into four different chapters. Each chapter presents the intervention of a specific day and is opened by the introduction, and followed by a conclusion by the coordinator of the same day. The four chapters are introduced by a forward by Gabriele Pasqui and essays by Guya Bertelli, Michele Roda and Pasquale Mei, reflecting a critical view on the role and the meaning of the public space in the contemporary city
Table_1_Susceptible and resistant olive cultivars show differential physiological response to Xylella fastidiosa infections.DOCX
No full textOlive quick decline syndrome (OQDS) is a severe disease, first described in Italy in late 2013, caused by strains of Xylella fastidiosa subsp. pauca (Xfp) in susceptible olive cultivars. Conversely, resistant olive cultivars do not develop OQDS but present scattered branch dieback, which generally does not evolve to severe canopy decline. In the present study, we assessed the physiological responses of Xfp-infected olive trees of susceptible and resistant cultivars. Periodic measurements of stomatal conductance (gs) and stem water potential (Ψstem) were performed using a set of healthy and Xfp-infected plants of the susceptible “Cellina di Nardò” and resistant “Leccino” and “FS17” cultivars. Strong differences in Δgs and ΔΨstem among Xfp-infected trees of these cultivars were found, with higher values in Cellina di Nardò than in Leccino and FS17, while no differences were found among healthy plants of the different cultivars. Both resistant olive cultivars showed lower water stress upon Xfp infections, compared to the susceptible one, suggesting that measurements of gs and Ψstem may represent discriminating parameters to be exploited in screening programs of olive genotypes for resistance to X. fastidiosa.</p
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