44,965 research outputs found
Heritability and Linkage Analysis of Appendicitis Utilizing Age at Onset
No full textAppendicitis usually afflicts the young, but there is a large tail in the distribution of onset age. The genetics of this disease are still not well understood. A heritability analysis and genome wide linkage analysis of a large twin dataset was undertaken. Treating age of onset of appendicitis as a censored survival trait revealed a heritability of 0.21, and found evidence of linkage to Chromosome 1p37.3. Author(s): Christopher Oldmeadow 1 * | Kerrie Mengersen 2 | Nicholas Martin 3 | David L. Duffy
Martin Nicholas and Carol Duval Outside the Bradenton Municipal Auditorium
No full textMartin Nicholas (left), unidentified person and Carol Duval (right) from the Manatee Players outside the Bradenton Municipal Auditorium.(100 10th Street West
The cult of St Nicholas in medieval Italy
No full textSt Nicholas was one of the most popular saints in medieval Italy. His cult attracted the attention
of popes, kings and emperors, and his shrine at Bari became an important international pilgrimage
destination. This thesis asks how the cult of St Nicholas came to be so widespread and popular in
Italy, and why the saint attracted the attention of diverse groups and individuals.
This thesis is structured around four chapters. The first demonstrates that through a
process of Latinisation the cult of St Nicholas became integrated within Italian literary traditions
and within a new spiritual era. Chapter Two reveals that this Latinisation also occurred within the
saint’s iconography. Chapters Three and Four are case studies of the cult in Puglia and Venice,
locations which claimed possession of the saint’s relics. These case studies show that the general
developments that the cult of St Nicholas underwent in Italy, identified in Chapters One and Two,
did not apply universally. Instead, the presence of the saint’s relics resulted in a different profile
of the saint in Bari and Venice. Through the process of Latinisation, the cult of St Nicholas
became updated and remained relevant for its new Italian audience; Chapters Three and Four
show alternative ways that the cult of St Nicholas gained widespread popularity.
This thesis presents for the first time an iconographical study of St Nicholas in Italian art,
which develops existing research of the saint’s Byzantine iconography. Chapter Four presents a
profile of the cult of St Nicholas in Venice in the Middle Ages, which is a significant oversight in
the literature. The thesis uses a variety of visual and textual sources, in particular fresco and
altarpiece representations, archival documents from Venice and Rome (including the Apostolic
Visitations), and under-exploited contemporary and antiquarian Venetian sources
Flexible Mx Specification of Various Extended Twin Kinship Designs
No full textThe extended twin kinship design allows the simultaneous testing of additive and nonadditive genetic, shared and individual-specific environmental factors, as well as sex differences in the expression of genes and environment in the presence of assortative mating and combined genetic and cultural transmission (Eaves et al., 1999). It also handles the contribution of these sources of variance to the (co)variation of multiple phenotypes. Keller et al. (2008) extended this comprehensive model for family resemblance to allow or a flexible specification of assortment and vertical transmission. As such, it provides a general framework which can easily be reduced to fit subsets of data such as twin-parent data, children-of-twins data, etc. A flexible Mx specification of this model that allows handling of these various designs is presented in detail and applied to data from the Virginia 30,000. Data on height, body mass index, smoking status, church attendance, and political affiliation were obtained from twins and their families. Results indicate that biases in the estimation of variance components depend both on the types of relative available for analysis, and on the underlying genetic and environmental architecture of the phenotype of interest. Author(s): Hermine H. Maes 1 * | Michael C. Neale 2 | Sarah E. Medland 3 | Matthew C. Keller 4 | Nicholas G. Martin 5 | Andrew C. Heath 6 | Lindon J. Eaves
Resolving the Iranian nuclear crisis : a review of policies and proposals 2006
No full textMartin F. Jakobsen; Nicholas Bowe
Martin (Dennis D.) Fifteenth-Century Carthusian Reform. The World of Nicholas Kempf
No full textSéguy Jean. Martin (Dennis D.) Fifteenth-Century Carthusian Reform. The World of Nicholas Kempf . In: Archives de sciences sociales des religions, n°86, 1994. pp. 294-295
Genetic covariation among facets of openness to experience and general cognitive ability
No full textGenetic and environmental sources of covariation among cognitive measures of verbal IQ, performance IQ (PIQ), academic achievement, 2-choice reaction time (CRT), inspection time (IT) and the 6 Openness facets of the NEO Personality Inventory-Revised (NEO PI-R) were examined. The number of twin and twin–sibling pairs ranged from 432 (182 MZ, 350 DZ/sibling) to 1023 (273 MZ, 750 DZ/sibling) for cognitive measures, and between 432 (90 MZ, 342 DZ/sibling) — 437 (91 MZ, 346 DZ/sibling) for Openness facets. Structural equation modeling best supported a model with a 3-factor additive genetic structure. A genetic general factor subsumed the 5 cognitive measures and 5 of the 6 Openness facets (Actions did not load significantly). A second additive genetic factor incorporated the 6 Openness facets, and a third additive genetic factor incorporated the 5 cognitive measures. Specific additive and dominance genetic effects were also evident, as were shared common and shared unique environmental influences, and specific unique environmental effects. The Openness facets of Ideas and Values evidenced the strongest phenotypic correlations with cognitive indices, particularly verbal measures. The genetic correlations among Openness facets and cognitive measures ranged from −.06 to .79. Results were interpreted as suggesting that Openness is related to general cognitive ability (g) through a genetic mechanism and that gengenders a minor but discernable disposition towards Openness for the majority of facets
View point: Stress test for the east: The Asian financial crisis has reached out to other emerging markets
No full textThe EBRD's Steven Fries, Nicholas Stern and Martin Raiser look at why the 'contagion' spread from east Asia to eastern Europ
- …
