1,721,051 research outputs found
Lumbosacral Plexopathy in Pelvic Radiotherapy: An Association not to be Neglected; A Systematic Review
No full text
Is there a potential role for EGFR expression to lead margin reduction in glioblastoma?
No full textWe started to investigate a potential role for EGFR protein expression in predicting the modality of treatment failure in glioblastoma after Stupp protocol, in terms of both time-to-progression (TTP) and pattern of
recurrence (PR) [central/in-field (C/I-F) vs. marginal/distant (M/D)]. EGFR expression is statistically correlated with
TTP (log-rank test: p = 0.003) and PR (Fisher’s exact test: p = 0.01). Our results seem to suggest that EGFR expression
might have a potential role for target contouring of RT volumes in GB patients that deserves further prospective investigations
Genomic Profiling: Can We Rely on Retrospective Analysis to Drive Changes in Clinical Practice?
No full textNutritional counselling for head and neck cancer patients treated with (chemo)radiation therapy: why, how, when, and what
In Regard to Kubicek et al.
Full text linkWe read the article “Stereotactic radiosurgery
for poor performance status patients” by Kubicek
et al recently published in your journal.
The authors concluded that patients with poor performance
status (PS) could be ideal candidates for stereotactic
radiosurgery (SRS), given the favorable logistics of singlefraction
treatment and a potential survival advantage. From
our point of view, however, further consideration needs to
be given regarding the use of these technologies in poor PS
patients
Persistent hiccup after chemo-radiotherapy in nasopharyngeal cancer: an atypical side effect?
Full text link
Temporal muscle thickness and survival in patients with amyotrophic lateral sclerosis
No full textTemporal muscle thickness (TMT) is a new potential MRI biomarker, which has shown prognostic relevance in neuro-oncology. We aim at investigating the potential prognostic value of TMT in patients with Amyotrophic Lateral Sclerosis (ALS). We retrospectively evaluated 30 ALS patients, whose clinical, Magnetic Resonance Imaging (MRI) and Electrodiagnostic testing (EDX) data were available, in comparison to age-matched 30 healthy subjects. TMT calculated on T1-weighted MR images was significantly lower in ALS patients than in healthy subjects (p < 0.001), correlating with the ALS Functional Rating Scale (FRS) (p:0.018) and compound motor action potential (CMAP) (p:0.012) in the patients group. Multivariate analysis of overall survival (OS) showed that the only parameters that remained significant were TMT (p:0.002, OR 0.45, 95%vCI: 0.28-0.75) and ALS FRS-R (p:0.023, OR: 0.80, 95%CI: 0.67-0.92). TMT seems to be a promising surrogate biomarker of survival and functional status in ALS. Our data deserve further investigations in multicenter and prospective trials
- …
