1,721,061 research outputs found
Epileptic encephalopathy in newborn [ENCEFALOPATIA EPILETTICA AD INSORGENZA NEONATALE]
On the basis of chronological, semeiological, etiological criteria and the course, it is possible to distinguish various types of myoclonic encephalopathies that begin in the first year of life. Early myoclonic encephalopathies mostly arise in the neonatal period and in the first 3 mth. They are characterized by almost continuous erratic myoclonias, spasms in flexion or extension, burst suppression type of EEG, and a course towards death or severe cerebral palsies. The classic syndrome of West (spasms in flexion, hypsarrhythmia and mental regression) can be distinguished from the incomplete West syndromes, in which one of the elements of the triad is missing. But this encephalopathy generally is of the same gravity as the classic West syndrome. It often develops into a Lennox-Gastaut syndrome. Dysmetabolic encephalopathies (early ceroid lipofuscinosis or Hagberg-Santavuori disease; GM2 gangliosidosis or Tay-Sachs disease; infantile progressive poliodystrophy of Christensen-Krabbe or Alpers disease) are manifested by hypotonia (which is then transformed into rigidity), mental regression, blindness, non-epileptic and epileptic myoclonia. They end in death. Myoclonic epilepsies with fixed encephalopathy generally are the result of perinatal or postnatal anoxia. There is microcephaly and mental retardation. The myoclonias and the EEG tracings are of the variable type. Particular forms are: the opsoclonic encephalopathy of Kinsbourne and the postanoxic encephalopathy of Lance-Adams
Going Beyond Counting First Authors in Author Co-citation Analysis
The present study examines one of the fundamental aspects of author co-citation analysis (ACA) - the way co-citation
counts are defined. Co-citation counting provides the data on which all subsequent statistical analyses and mappings
are based, and we compare ACA results based on two different types of co-citation counting - the traditional type that
only counts the first one among a cited work's authors on the one hand and a non-traditional type that takes into
account the first 5 authors of a cited work on the other hand. Results indicate that the picture produced through this non-traditional author co-citation counting contains more coherent author groups and is therefore considerably clearer. However, this picture represents fewer specialties in the research field being studied than that produced through the traditional first-author co-citation counting when the same number of top-ranked authors is selected and analyzed. Reasons for these effects are discussed
Variations on the Author
“Variations on the Author” discusses two of Eduardo Coutinho’s recent films (Um Dia na Vida, from 2010, and Últimas Conversas, posthumously released in 2015) and their contribution to the general question of documentary authorship. The director’s filmography is characterized by a consistent yet self-effacing form of authorial self-inscription: Coutinho often features as an interviewer that rather than express opinions propels discourses; an interviewer that is good at listening. This mode of self-inscription characterizes him as an author who is not expressive but who is nonetheless markedly present on the screen. In Um Dia na Vida, however, Coutinho is completely absent form the image, while Últimas Conversas, on the contrary, includes a confessional prologue that moves the director from the margins to the center of his films. This article examines the ways in which these works stand out in the filmography of a director who offers new insights into the notion of cinematic authorship
Reduced ACTH, while normal beta-endorphin CSF levels in early epileptic encephalopathies.
Since ACTH and the opioids display opposite effects on experimentally-induced seizures, cerebrospinal fluid (CSF) levels of ACTH and beta-endorphin (beta-EP) were measured in 6 children (4-8 months) affected by infantile spasms with hypsarhythmia, an idiopathic early onset encephalopathy, and in 8 age-matched controls. beta-EP levels in the patients (76.3 +/- 14.7 fmol/ml, M +/- SD) did not differ from those in controls (109.8 +/- 42.7) while babies with epileptic encephalopathy showed reduced ACTH levels in the CSF (3.8 +/- 1.5) as compared to controls (9.0 +/- 3.7, p less than 0.01). This resulted in an increased beta-EP/ACTH ratio. Another patient previously treated with ACTH showed a normal CSF level of ACTH (9.0) with a normal beta-EP/ACTH ratio while in clinical and EEG remission. These results are consistent with the hypothesis that some infantile seizures unrelated to brain injuries could originate from an ACTH deficiency at central level and/or an imbalance of neuropeptidergic pathways
Ultrasonic evaluation of the cranial theca thickness through the growth period in infancy and childhood.
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L'elettroencefalogramma nelle convulsioni neonatali: possibilità diagnostiche e prognostiche
A clinical approache to newborn epilepsy must start for the careful description of seizures even in the period life. The permits us to classift correctly neoantal seizure; methodical post-mortem correlative studies could laed us to a better comprehension of their pathogenic mechanism.EEG-poligraphic records significance in diagnosis and prognosis is also stressed.Repetitive sharp waves formed the most frequent critical pattern; during virtually "generalised" seizures tonic and clinic phase cliniccaly and electrically distinguished are illustrated.Critic anachronostic activities (alpha and theta-like) were observed in one case.Flat tracings or repetitive slow waves (delta waves) activity were found in prterm babies during apnoeic or tonic attacks and in at term ones during the rare tonic seizures.; they generally corresponded to a severe CNS damage destructive in nature and ha a bad prognosis oten evolving in a West hypsarrhytmia.In so called " atypical seizures" the importance of EEG-poligraphic monitorin emerges.As well Known, inactive or low voltage tracing and periodic intercritical activities had an unvarouable prognosis.The possible development of a West syndrome from a persisting anterocentral show dyshrytmia is proved.Amultidocal paroxysmal activity in interseizure phases involved a bad significance.On the contrary, continuous theta-like rhythms on a precedent paroxysmal activity, if rapidly and completely established, were always followed by a good evolution in our series
LA FONCTION VISUELLE CHEZ LE NOUVEAU-NES SAINS A TERME ET CHEZ LES PREMATURES PARVENUS AU MEME AGE CONCEPTIONEL
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