104 research outputs found
Examining the Association Between Diabetes and Hypertension Among Women 40 Years and Older Using the Framingham Study
No full textObjectives: To investigate the association between diabetes and hypertension over 24 years using the Framingham Heart Study in women 40 or older.
Methods: The study utilized a subset of data from the Framingham Study (initiated in 1948), a longitudinal prospective cohort study, which followed participants for 24 years. The exposure was diabetes, while hypertension was the outcome. Women aged 40 years or older who had no missing data on diabetes or hypertension were included (N=2,187). Logistic regression was used to estimate unadjusted and adjusted odds ratios (OR) and 95% confidence intervals (CI). Adjusted models controlled for body mass index, smoking, and total cholesterol. A secondary stratified analysis was conducted to evaluate effect modification by total cholesterol.
Results: In the unadjusted model, women with diabetes had 2.72 times the odds of having hypertension compared with those without diabetes (95% CI: 1.16-6.35). In the adjusted model, diabetes was not statistically significantly associated with hypertension (adjusted OR 1.99, 95% CI: 0.82-4.81).
Conclusion: The results support the development of public policy and programs involving diabetes and cardiovascular disease and can guide future research
A 64 channels 14-bit 50 MS/sec data acquisition card with real time processing in VME form factor
No full textApplication of the Vulnerability Estimator for Spring Protection Areas (VESPA index) in mountain quaternary aquifers
No full textEstablishment of Russian Oncology before the Great Patriotic War
No full textThe establishment of oncology as a discipline in Russia should be considered taking into account the specifics of national history, as well as key historical events. In 2020, Russia celebrates the 75th anniversary of Victory in the Great Patriotic War (World Was II). Russian oncology also celebrates its 75th anniversary. April 30, 1945 is considered the birthday of the Russian oncological service connected with the publication of a historical resolution of the Council of People’s Commissars of the USSR No. 935 “On measures to improve oncological care to population.”In pre-revolutionary Russia, oncological care had the character of a private initiative, rather than a well-organised process. The tsarist government did not bear responsibility for organising the fight against cancer. The Great October Socialist Revolution contributed to the organisation of the fight against malignant neoplasms at the state level, based on the decisions of party congresses and healthcare laws. This created favourable conditions for improving and expanding anticancer care to the population. Soviet scientists-enthusiasts made a significant contribution to the development of oncology in the USSR. The organisation of medical professional societies facilitated the determination of main directions in the development of oncology as a discipline in the country. By the beginning of World War II, oncology in the USSR had acquired the character of an oncological care system, implementing measures aimed at developing and transferring into clinical practice early detection methods and those of treating malignant tumours, as well as their prevention. By the beginning of World War II, this system had comprised a large number of oncological dispensaries, located in almost all the republics of the Soviet Union. However, at that moment, there was still no unity in the creation of practical oncological institutions. Neither was practiced the registration of cancer cases, their account and observation, which measures are necessary for the prevention and early diagnosis of malignant tumours and precancerous diseases
Variations in the boron isotopic and elemental composition in modern brachiopods: Assessing the biomineralization processes in the shell microstructure
No full textThe boron isotope composition (commonly expressed as δ11B) of marine calcium carbonate is one of the most reliable pH proxies (e.g. Vengosh et al., 1991; Hemming and Hanson, 1992). In this context, brachiopods are a potential archive due to their great abundance in the geological record and their low-magnesium calcite shells that make them more resistant to diagenetic alteration (e.g. Lowenstam, 1961; Veizer et al., 1986). This study focuses on the impact of brachiopod shell biomineralization processes on the boron isotopic and elemental (B/Ca) compositions. Boron isotope analyses were performed at the micrometer scale by ion microprobe, and by laser ablation (LA) coupled to a MC-ICP-MS to create 2D images, while B/Ca was determined using LA-ICP-MS in shells of five modern brachiopods species composed of primary (PL) and secondary layer (SL) (Terebratalia transversa, Magasella sanguinea, Notosaria nigricans, Calloria inconspicua and Magellania venosa) and one species composed also with tertiary layer (TL) (Liothyrella neozelanica). Our results show that the PL is slightly depleted in 11B relative to the SL and higher in B/Ca. The SL layer does not show a specific trend of δ11B from the outermost to the innermost shell thickness. B/Ca ratio goes towards lower values in the innermost regions of the shell likely due to kinetic effects, as less boron is incorporated as growth rates slow. Values obtained here are similar to those previously published (Lécuyer et al., 2002; Penman et al., 2013). Regarding the TL, B/Ca values are lower than in PL and SL. We will further explore the mechanisms responsible for such differences in δ11B and B/Ca values between the different shell layers and its potential use as palaeo-pH proxy. Hemming, N., Hanson, G., 1992. Boron isotopic composition and concentration in modern marine carbonates. Geochim. Cosmochim. Acta 56, 537-543. Lécuyer, C., Grandjean, P., Reynard, B., Albarède, F., Telouk, P., 2002. 11B/10B analysis of geological materials by ICP-MS Plasma 54: application to the boron fractionation between brachiopod calcite and seawater. Chem. Geol. 186 (1-2), 45-55. Lowenstam, H.A., 1961. Mineralogy, O-18/O-16 ratios, and strontium and magnesium contents of recent and fossil brachiopods and their bearing on the history of the oceans. J. Geol. 69, 241-260. Penman, D.E., Hönisch B., Rasbury E.T. Hemming, N.G., Howard J.S, 2013. Boron, carbon, and oxygen isotopic composition of brachiopod shells: Intra-shell variability, controls, and potential as a paleo-pH recorder. Chem. Geol. 340, 32-39. Veizer, J., Fritz, P., Jones, B., 1986. Geochemistry of brachiopods: oxygen and carbon isotopic records of Paleozoic oceans. Geochim. Cosmochim. Acta 50, 1679-1696. Vengosh, A., Kolodny, Y., Starinsky, A., Chivas, A.R., McCulloch, M.T., 1991. Co- precipitation and isotopic fractionation of boron in modern biogenic carbonates. Geochim. Cosmochim. Acta 55, 2901-2910
The Belle II Physics Book (Dec, 10.1093/ptep/ptz106, 2019) - correction
No full textAutorzy: Kou, E., Urquijo, P., Altmannshofer, W., Beaujean, F., Bell, G., Beneke, M., Bigi, I.I., Bishara, F., Blanke, M., Bobeth, C., Bona, M., Brambilla, N., Braun, V.M., Brod, J., Buras, A.J., Cheng, H.Y., Chiang, C.W., Ciuchini, M., Colangelo, G., Crivellin, A., Czyz, H., Datta, A., De Fazio, F., Deppisch, T., Dolan, M.J., Evans, J., Fajfer, S., Feldmann, T., Godfrey, S., Gronau, M., Grossman, Y., Guo, F.K., Haisch, U., Hanhart, C., Hashimoto, S., Hirose, S., Hisano, J., Hofer, L., Hoferichter, M., Hou, W.S., Huber, T., Hurth, T., Jaeger, S., Jahn, S., Jamin, M., Jones, J., Jung, M., Kagan, A.L., Kahlhoefer, F., Kamenik, J.F., Kaneko, T., Kiyo, Y., Kokulu, A., Kosnik, N., Kronfeld, A.S., Ligeti, Z., Logan, H., Lu, C.D., Lubicz, V., Mahmoudi, F., Maltman, K., Mishima, S., Misiak, M., Moats, K., Moussallam, B., Nefediev, A., Nierste, U., Nomura, D., Offen, N., Olsen, S.L., Passemar, E., Paul, A., Paz, G., Petrov, A.A., Pich, A., Polosa, A.D., Pradler, J., Prelovsek, S., Procura, M., Ricciardi, G., Robinson, D.J., Roig, P., Rosiek, J., Schacht, S., Schmidt-Hoberg, K., Schwichtenberg, J., Sharpe, S.R., Shigemitsu, J., Shih, D., Shimizu, N., Shimizu, Y., Silvestrini, L., Simula, S., Smith, C., Stoffer, P., Straub, D., Tackmann, F.J., Tanaka, M., Tayduganov, A., Tetlalmatzi-Xolocotzi, G., Teubner, T., Vairo, A., Van Dyk, D., Virto, J., Was, Z., Watanabe, R., Watson, I., Westhoff, S., Zupan, J., Zwicky, R., Abudinén, F., Adachi, I., Adamczyk, K., Ahlburg, P., Aihara, H., Aloisio, A., Andricek, L., Anh Ky, N., Arndt, M., Asner, D.M., Atmacan, H., Aushev, T., Aushev, V., Ayad, R., Aziz, T., Baehr, S., Bahinipati, S., Bambade, P., Ban, Y., Barrett, M., Baudot, J., Behera, P., Belous, K., Bender, M., Bennett, J., Berger, M., Bernieri, E., Bernlochner, F.U., Bessner, M., Besson, D., Bettarini, S., Bhardwaj, V., Bhuyan, B., Bilka, T., Bilmis, S., Bilokin, S., Bonvicini, G., Bozek, A., Bračko, M., Branchini, P., Braun, N., Briere, R.A., Browder, T.E., Burmistrov, L., Bussino, S., Cao, L., Caria, G., Casarosa, G., Cecchi, C., Červenkov, D., Chang, M.-C., Chang, P., Cheaib, R., Chekelian, V., Chen, Y., Cheon, B.G., Chilikin, K., Cho, K., Choi, J., Choi, S.-K., Choudhury, S., Cinabro, D., Cremaldi, L.M., Cuesta, D., Cunliffe, S., Dash, N., De La Cruz Burelo, E., De Lucia, E., De Nardo, G., De Nuccio, M., De Pietro, G., De Yta Hernandez, A., Deschamps, B., Destefanis, M., Dey, S., Di Capua, F., Di Carlo, S., Dingfelder, J., Doležal, Z., Domínguez Jiménez, I., Dong, T.V., Dossett, D., Duell, S., Eidelman, S., Epifanov, D., Fast, J.E., Ferber, T., Fiore, S., Fodor, A., Forti, F., Frey, A., Frost, O., Fulsom, B.G., Gabriel, M., Gabyshev, N., Ganiev, E., Gao, X., Gao, B., Garg, R., Garmash, A., Gaur, V., Gaz, A., Geßler, T., Gebauer, U., Gelb, M., Gellrich, A., Getzkow, D., Giordano, R., Giri, A., Glazov, A., Gobbo, B., Godang, R., Gogota, O., Goldenzweig, P., Golob, B., Gradl, W., Graziani, E., Greco, M., Greenwald, D., Gribanov, S., Guan, Y., Guido, E., Guo, A., Halder, S., Hara, K., Hartbrich, O., Hauth, T., Hayasaka, K., Hayashii, H., Hearty, C., Heredia De La Cruz, I., Hernandez Villanueva, M., Hershenhorn, A., Higuchi, T., Hoek, M., Hollitt, S., Hong Van, N.T., Hsu, C.-L., Hu, Y., Huang, K., Iijima, T., Inami, K., Inguglia, G., Ishikawa, A., Itoh, R., Iwasaki, Y., Iwasaki, M., Jackson, P., Jacobs, W.W., Jaegle, I., Jeon, H.B., Ji, X., Jia, S., Jin, Y., Joo, C., Künzel, M., Kadenko, I., Kahn, J., Kakuno, H., Kaliyar, A.B., Kandra, J., Kang, K.H., Kato, Y., Kawasaki, T., Ketter, C., Khasmidatul, M., Kichimi, H., Kim, J.B., Kim, K.T., Kim, H.J., Kim, D.Y., Kim, K., Kim, Y., Kimmel, T.D., Kindo, H., Kinoshita, K., Konno, T., Korobov, A., Korpar, S., Kotchetkov, D., Kowalewski, R., Križan, P., Kroeger, R., Krohn, J.-F., Krokovny, P., Kuehn, W., Kuhr, T., Kulasiri, R., Kumar, M., Kumar, R., Kumita, T., Kuzmin, A., Kwon, Y.-J., Lacaprara, S., Lai, Y.-T., Lalwani, K., Lange, J.S., Lee, S.C., Lee, J.Y., Leitl, P., Levit, D., Levonian, S., Li, S., Li, L.K., Li, Y., Li, Y.B., Li, Q., Li Gioi, L., Libby, J., Liptak, Z., Liventsev, D., Longo, S., Loos, A., Lopez Castro, G., Lubej, M., Lueck, T., Luetticke, F., Luo, T., Müller, F., Müller, T., Macqueen, C., Maeda, Y., Maggiora, M., Maity, S., Manoni, E., Marcello, S., Marinas, C., Martinez Hernandez, M., Martini, A., Matvienko, D., Mckenna, J.A., Meier, F., Merola, M., Metzner, F., Miller, C., Miyabayashi, K., Miyake, H., Miyata, H., Mizuk, R., Mohanty, G.B., Moon, H.K., Moon, T., Morda, A., Morii, T., Mrvar, M., Muroyama, G., Mussa, R., Nakamura, I., Nakano, T., Nakao, M., Nakayama, H., Nakazawa, H., Nanut, T., Naruki, M., Nath, K.J., Nayak, M., Nellikunnummel, N., Neverov, D., Niebuhr, C., Ninkovic, J., Nishida, S., Nishimura, K., Nouxman, M., Nowak, G., Ogawa, K., Onishchuk, Y., Ono, H., Onuki, Y., Pakhlov, P., Pakhlova, G., Pal, B., Paoloni, E., Park, H., Park, C.-S., Paschen, B., Passeri, A., Paul, S., Pedlar, T.K., Perelló, M., Peruzzi, I.M., Pestotnik, R., Piilonen, L.E., Podesta Lerma, L., Popov, V., Prasanth, K., Prencipe, E., Prim, M., Purohit, M.V., Rabusov, A., Rasheed, R., Reiter, S., Remnev, M., Resmi, P.K., Ripp-Baudot, I., Ritter, M., Ritzert, M., Rizzo, G., Rizzuto, L., Robertson, S.H., Rodriguez Perez, D., Roney, J.M., Rosenfeld, C., Rostomyan, A., Rout, N., Rummel, S., Russo, G., Sahoo, D., Sakai, Y., Salehi, M., Sanders, D.A., Sandilya, S., Sangal, A., Santelj, L., Sasaki, J., Sato, Y., Savinov, V., Scavino, B., Schram, M., Schreeck, H., Schueler, J., Schwanda, C., Schwartz, A.J., Seddon, R.M., Seino, Y., Senyo, K., Seon, O., Seong, I.S., Sevior, M.E., Sfienti, C., Shapkin, M., Shen, C.P., Shimomura, M., Shiu, J.-G., Shwartz, B., Sibidanov, A., Simon, F., Singh, J.B., Sinha, R., Skambraks, S., Smith, K., Sobie, R.J., Soffer, A., Sokolov, A., Solovieva, E., Spruck, B., Stanič, S., Starič, M., Starinsky, N., Stolzenberg, U., Stottler, Z., Stroili, R., Strube, J.F., Stypula, J., Sumihama, M., Sumisawa, K., Sumiyoshi, T., Summers, D., Sutcliffe, W., Suzuki, S.Y., Tabata, M., Takahashi, M., Takizawa, M., Tamponi, U., Tan, J., Tanaka, S., Tanida, K., Taniguchi, N., Tao, Y., Taras, P., Tejeda Munoz, G., Tenchini, F., Tippawan, U., Torassa, E., Trabelsi, K., Tsuboyama, T., Uchida, M., Uehara, S., Uglov, T., Unno, Y., Uno, S., Ushiroda, Y., Usov, Y., Vahsen, S.E., Van Tonder, R., Varner, G., Varvell, K.E., Vinokurova, A., Vitale, L., Vos, M., Vossen, A., Waheed, E., Wakeling, H., Wan, K., Wang, M.-Z., Wang, X.L., Wang, B., Warburton, A., Webb, J., Wehle, S., Wessel, C., Wiechczynski, J., Wieduwilt, P., Won, E., Xu, Q., Xu, X., Yabsley, B.D., Yamada, S., Yamamoto, H., Yan, W., Yan, W., Yang, S.B., Ye, H., Yeo, I., Yin, J.H., Yonenaga, M., Yoshinobu, T., Yuan, W., Yuan, C.Z., Yusa, Y., Zakharov, S., Zani, L., Zeyrek, M., Zhang, J., Zhang, Y., Zhang, Y., Zhou, X., Zhukova, V., Zhulanov, V., Zupanc, A.This is a correction to:
Progress of Theoretical and Experimental Physics, Volume 2019, Issue 12, December 2019, 123C01, https://doi.org/10.1093/ptep/ptz10
XRF data from marine core KL 15 taken in Gulf of Aden during R/V Meteor cruise 5/2
No full textHere, we present data from the marine core from Meteor Site KL 15 drilled in 1987 during R/V Meteor cruise 5/2 at station 259 (12.85738°N, 47.41707°E). The XRF data was measured using the Avvatech XRF Core Scanner III (Serial No. 12) at MARUM (Bremen, Germany). As summarized in the age model, the record spans the past 546 thousand years at a high sampling resolution of 1 cm with a total core length of 21.67 m. The XRF data has three major groups, as explained in detail in our related research article: The first group includes the subgroup of aluminum and silicon, potassium, iron and titanium, zirconium, and rubidium. The second group is strontium and calcium, and the third group, with the highest Euclidian distance to the rest of the dataset, includes only bromine. Sediment composition at Meteor Site KL 15 is predominantly controlled by carbonate, as suggested by the high carbonate contents of ca. 56% and their variability of 45 to 65% (Stein et al., 2007). In our related research article, we use the log ratio of titanium and aluminum as a proxy for aeolian input
Необходимость проведения микционной цистоуретрографии для оценки взрослых кандидатов на трансплантацию почки
No full textObjective. While international guidelines necessitate Voiding Cystourethrogram (VCUG) for pediatric patients, it is unnecessary for the evaluation of adult patients without urological disorders as renal transplant candidates. The objective of this study was to evaluate the results of adult candidates who underwent VCUG before transplantation and to demonstrate the necessity for this imaging. Methods. A retrospective study of the data of 1265 adult candidates who underwent VCUG before transplantation at our center, was undertaken. VUR, the presence of Postvoiding residual urine (PVR) (>100 ml), Low bladder capacity (LBC) (<100 ml), and urethral pathologies were evaluated with VCUG. Results. The mean age was 42.3 ± 1.3. The mean dialysis period was 27.8 ± 4.2 months. According to the VCUG results, 19.2% of the patients had pathological findings. On the other hand, the rate of urological disorders was only 5.1%, according to end-stage renal disease (ESRD) etiologies. VCUG outcomes indicated bilateral high-grade reflux in native kidneys in 4.4% (n = 56) of the candidates, unilateral high-grade reflux in 4.1% (n = 52), bilateral low grade reflux in 2.1% (n = 26), unilateral low-grade reflux in 2.4% (n = 30), and reflux in rejected transplanted kidney in 2.3% (n = 29). In addition, significant LBC was noted in 4.8% (n = 61), significant PVR in 1.1% (n = 14), and urethral stricture in 0.5% (n = 6) of the candidates. Conclusion. VCUG should be considered as a part of routine evaluation in adult renal transplant recipient candidates as well as in pediatric candidates, even if their ESRD etiologies are not due to urological disorders.В то время как во всех международных протоколах при подготовке к трансплантации почки в педиатрической практике потенциальным реципиентам предписано обязательно проводить микционную цисто уретрографию (МЦУГ), нет никаких указаний относительно этого перед проведением трансплантации почки взрослым пациентам без урологических нарушений. Цель: оценить результативность МЦУГ, проведенной перед трансплантацией взрослым пациентам, и необходимость использования этого метода визуализации перед операцией. Материалы и методы. Было проведено ретроспективное исследова ние данных 1265 взрослых реципиентов почки, которым выполняли МЦУГ перед трансплантацией в нашем центре. С помощью МЦУГ оценивали наличие и степень пузырно-мочеточникового рефлюкса (ПМР), остаточный объем мочи после мочеиспускания (PVR) (>100 мл), емкость мочевого пузыря (низ кая емкость мочевого пузыря <100 мл) и патологию мочеиспускательного канала. Результаты. Средний возраст пациентов составил 42,3 ± 1,3 года. В среднем пациенты находились на диализе 27,8 ± 4,2 ме сяца. По результатам МЦУГ у 19,2% пациентов были обнаружены патологические изменения. С другой стороны, урологические нарушения были причиной терминальной почечной недостаточности (ТПН) всего в 5,1% случаев. По результатам МЦУГ были выявлены двусторонний ПМР тяжелой степени в нативных почках у 4,4% (n = 56) потенциальных реципиентов, односторонний ПМР тяжелой степени – у 4,1% (n = 52), двусторонний ПМР легкой степени – в 2,1% (n = 26), односторонний ПМР легкой степени тяжести – у 2,4% (n = 30) и рефлюкс в трансплантат почки при его отторжении – у 2,3% (n = 29). Кроме того, обнаружено значительное снижение емкости мочевого пузыря у 4,8% (n = 61), значительное сниже ние PVR – у 1,1% (n = 14) и стриктура уретры – у 0,5% (n = 6) потенциальных реципиентов. Заключение. Следует рассмотреть целесообразность включения в повседневную клиническую практику МЦУГ для оценки функционального состояния мочевыводящих путей взрослых потенциальных реципиентов перед трансплантацией почки, а также реципиентов-детей, даже если ТПН не обусловлена урологическими заболеваниями
Становление российской онкологической службы после Великой Отечественной войны
No full textOncology was officially acknowledged as a separate branch of medical science 75 years ago. Historically, it was landmarked by Order No. 323 of the People’s Commissariat for Health of the USSR of April 30, 1945 “On efforts to improve national oncology care”. This decision triggered deployment of a network of oncological institutions that covered almost the entire country in relatively short time and persists today. Aside to rapid revival of existing cancer institutions, new research centres for oncology and radiology, cancer dispensaries and rooms were being set up to gear universal and comprehensive case archival, due-time tumour diagnostics and vocational training, along with manifold other measures to contain cancer. A milestone event was the erection of the Oncological Society in 1954 by the Scientific Council Presidium of the USSR Ministry of Health. The Moscow and All-Union oncological societies contributed greatly to establishment of the Oncology Service and promoted the prestige of Soviet oncology, professional activity in the Union’s republics and overall effectiveness against cancer. Involvement of outstanding scientists, leading oncologists and healthcare decision makers in fostering the Oncology Service cannot be overstated. Today, a progress is made towards understanding the roots of cancer, supply of medical institutions with state-of-the-art equipment, implementation of effective diagnostic and therapy practices. Nevertheless, as yet timely remain further enhancement of preventive medicine, deployment of regional programs for cancer monitoring, education and higher-level professional training, remodelling of diagnostics and care in specialised oncological and primary medical institutions, creation of a unified system for prevention, earlier diagnosis and treatment of cancer.Онкология 75 лет назад официально была признана самостоятельной медицинской дисциплиной. Историческим событием стал Приказ № 323 Наркомздрава СССР от 30 апреля 1945 г. «О борьбе по улучшению онкологической помощи населению». Этим решением была развернута сеть онкологических учреждений, охватившая практически все регионы страны за относительно короткий промежуток времени и существующая в настоящее время. Наряду с быстрым восстановлением существующих онкологических учреждений открывались новые научно-исследовательские институты онкологии и рентгенорадиологии, онкологические диспансеры и кабинеты, организовывалась повсеместная система учета онкологических больных и своевременной диагностики опухолей, формировалась подготовка кадров и проводилось множество других мероприятий по борьбе с онкологическими заболеваниями. Одним из важных событий в онкологии стало создание в 1954 г. по решению президиума Ученого совета Минздрава СССР Общества онкологов. Московским и Всесоюзным обществами онкологов был внесен значимый вклад в формирование онкологической службы. Они способствовали росту престижа советской онкологии, активности онкологов союзных республик, эффективности противораковой борьбы. Невозможно переоценить вклад в становление онкологической службы выдающихся ученых, организаторов здравоохранения, главных онкологов страны. В настоящее время достигнуты успехи в изучении при- чин возникновения рака, в оснащении медицинских организаций современным высокоэффективным оборудованием, во внедрении эффективных диагностических и лечебных методик в клиническую практику. Однако по-прежнему остаются актуальными проблемы дальнейшего совершенствования профилактической работы; разработки и внедрения территориальных программ по противораковой борьбе; подготовки, переподготовки и повышения уровня квалификации кадров; модернизации лечебно-диагностического процесса в специализированных онкологических учреждениях и учреждениях первичного звена здравоохранения; создания единой системы профилактики, ранней диагностики и лечения онкологических заболеваний
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